{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,2]],"date-time":"2026-02-02T01:12:58Z","timestamp":1769994778362,"version":"3.49.0"},"reference-count":21,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2025,11,21]],"date-time":"2025-11-21T00:00:00Z","timestamp":1763683200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2025,11,21]],"date-time":"2025-11-21T00:00:00Z","timestamp":1763683200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100004587","name":"Instituto de Salud Carlos III","doi-asserted-by":"publisher","award":["CB21\/13\/00091"],"award-info":[{"award-number":["CB21\/13\/00091"]}],"id":[{"id":"10.13039\/501100004587","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100012781","name":"Merck Sharp and Dohme K.K.","doi-asserted-by":"publisher","award":["IISP59172"],"award-info":[{"award-number":["IISP59172"]}],"id":[{"id":"10.13039\/100012781","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["HIV Medicine"],"published-print":{"date-parts":[[2026,2]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objectives and Design<\/jats:title>\n                    <jats:p>We aimed to describe pregnancies among women who were diagnosed with HIV during pregnancy in a multicentre cohort.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We included antiretroviral (ART)\u2010na\u00efve women, aged 18\u201350\u2009years, who were recruited into the Spanish CoRIS cohort between 2004 and 2022 and had been diagnosed with HIV during pregnancy.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Of 2102 women, 185 (8.8%) were diagnosed with HIV during pregnancy, 51.2% of which were late presenters, and 25.4% and 9.2% were diagnosed during the second and third trimester, respectively. Women from Latin America (adjusted odds ratio [OR]: 4.97, 95% CI: 1.72; 14.35) and Sub\u2010Saharan Africa (3.07, 1.11; 8.52) were more likely to be diagnosed after the first trimester compared to Spanish women. Overall, 95.7% initiated ART during pregnancy, at a median time of 2\u2009days (interquartile range [IQR]: 0; 14) from enrolment. Over time, the use of emtricitabine+tenofovir disoproxil fumarate (and later emtricitabine+tenofovir alafenamide), as well as integrase strand transfer inhibitors, increased. Overall, 95.1% of pregnancies resulted in delivery (46.0% caesarean). At 36\u2009weeks of pregnancy, 82.8% of women had an undetectable viral load (VL), rising from 71.7% in 2004\u20132008 to over 95% after 2013. Preterm birth and low birth weight occurred in 10% and 9.8% of deliveries, respectively, with one HIV perinatal transmission.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Among women diagnosed with HIV during pregnancy, half were late presenters, and one\u2010third were diagnosed after the first trimester, with higher percentages among African and Latin American women. There was a high proportion of caesarean deliveries. Most women initiated ART promptly after cohort enrolment and achieved undetectable VL at the end of pregnancy.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/hiv.70148","type":"journal-article","created":{"date-parts":[[2025,11,21]],"date-time":"2025-11-21T08:47:28Z","timestamp":1763714848000},"page":"270-282","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Diagnosis of\n                    <scp>HIV<\/scp>\n                    infection during pregnancy: Trends from a national cohort in Spain"],"prefix":"10.1111","volume":"27","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7016-716X","authenticated-orcid":false,"given":"In\u00e9s","family":"Su\u00e1rez\u2010Garc\u00eda","sequence":"first","affiliation":[{"name":"Infectious Diseases Group, Department of Internal Medicine, Infanta Sof\u00eda University Hospital Infanta Sofia University Hospital and Henares University Hospital Foundation for Biomedical Research and Innovation (FIIB HUIS HHEN)  Madrid Spain"},{"name":"Department of Medicine, Faculty of Medicine, Health and Sports Universidad Europea de Madrid  Madrid Spain"},{"name":"CIBERINFEC, Carlos III Health Institute  Madrid Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bel\u00e9n","family":"Alejos","sequence":"additional","affiliation":[{"name":"Independent researcher  Madrid Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cristina","family":"Moreno","sequence":"additional","affiliation":[{"name":"CIBERINFEC, Carlos III Health Institute  Madrid Spain"},{"name":"National Centre for Epidemiology Carlos III Health Institute  Madrid Spain"},{"name":"Programa de Doctorado en Ciencias Biom\u00e9dicas y Salud P\u00fablica. IMIENS. Universidad Nacional de Educaci\u00f3n a Distancia (UNED)  Madrid Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5780-4462","authenticated-orcid":false,"given":"Rebeca","family":"Izquierdo","sequence":"additional","affiliation":[{"name":"CIBERINFEC, Carlos III Health Institute  Madrid Spain"},{"name":"National Centre for Epidemiology Carlos III Health Institute  Madrid Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9122-6897","authenticated-orcid":false,"given":"Santiago P\u00e9rez","family":"de la C\u00e1mara","sequence":"additional","affiliation":[{"name":"Telemedicine and E\u2010Health Unit, Carlos III Health Institute  Madrid Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Patricia","family":"Resa\u2010Infante","sequence":"additional","affiliation":[{"name":"CIBERINFEC, Carlos III Health Institute  Madrid Spain"},{"name":"IrsiCaixa  Badalona Spain"},{"name":"University of Vic\u2013Central University of Catalonia  Vic Spain"},{"name":"Germans Trias i Pujol Research Institute  Badalona Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"V\u00edctor S\u00e1nchez","family":"Merino","sequence":"additional","affiliation":[{"name":"CIBERINFEC, Carlos III Health Institute  Madrid Spain"},{"name":"National Microbiology Centre Carlos III Health Institute  Madrid Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5167-5724","authenticated-orcid":false,"given":"Juan","family":"Garc\u00eda\u2010Arriaza","sequence":"additional","affiliation":[{"name":"CIBERINFEC, Carlos III Health Institute  Madrid Spain"},{"name":"Department of Molecular and Cellular Biology Centro Nacional de Biotecnolog\u00eda. Consejo Superior de Investigaciones Cient\u00edficas  Madrid Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8429-8358","authenticated-orcid":false,"given":"Alfonso","family":"Cabello\u2010\u00dabeda","sequence":"additional","affiliation":[{"name":"Divisi\u00f3n de Enfermedades Infecciosas Hospital Universitario Fundaci\u00f3n Jim\u00e9nez D\u00edaz. IIS\u2010FJD  Madrid Spain"},{"name":"Universidad Aut\u00f3noma de Madrid  Madrid Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Laura","family":"P\u00e9rez\u2010Mart\u00ednez","sequence":"additional","affiliation":[{"name":"Centro de Investigaci\u00f3n Biom\u00e9dica de La Rioja (CIBIR) Hospital Universitario San Pedro de La Rioja  Logro\u00f1o Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rosario","family":"Palacios","sequence":"additional","affiliation":[{"name":"Unidad de Enfermedades Infecciosas Hospital Universitario Virgen de la Victoria, IBIMA  M\u00e1laga Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2762-4924","authenticated-orcid":false,"given":"Victoria","family":"Hernando","sequence":"additional","affiliation":[{"name":"CIBERINFEC, Carlos III Health Institute  Madrid Spain"},{"name":"National Centre for Epidemiology Carlos III Health Institute  Madrid Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Inma","family":"Jarr\u00edn","sequence":"additional","affiliation":[{"name":"CIBERINFEC, Carlos III Health Institute  Madrid Spain"},{"name":"National Centre for Epidemiology Carlos III Health Institute  Madrid Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"name":"the CoRIS cohort","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,11,21]]},"reference":[{"key":"e_1_2_12_2_1","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/ciac703"},{"key":"e_1_2_12_3_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0223536"},{"key":"e_1_2_12_4_1","doi-asserted-by":"publisher","DOI":"10.1097\/QAD.0000000000000212"},{"key":"e_1_2_12_5_1","unstructured":"Ministerio de Sanidad SSeI.Gu\u00eda de pr\u00e1ctica cl\u00ednica de atenci\u00f3n en el embarazo y puerperio. 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