{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,13]],"date-time":"2026-03-13T14:58:29Z","timestamp":1773413909596,"version":"3.50.1"},"reference-count":33,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2025,12,10]],"date-time":"2025-12-10T00:00:00Z","timestamp":1765324800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2025,12,10]],"date-time":"2025-12-10T00:00:00Z","timestamp":1765324800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["HIV Medicine"],"published-print":{"date-parts":[[2026,3]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>Initial HIV cure interventions may not meet expert\u2010defined target product profiles (TPPs; desired treatment attributes). Understanding how people with HIV perceive ideal and likely HIV cure attributes is essential. This study examined which optimal TPP attributes people with HIV consider important and which minimum attributes and strategies they find acceptable. Additionally, it explored patterns of importance and their association with the acceptance of minimum attributes and cure strategies.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A cross\u2010sectional survey (July 2023\u2013March 2024) among 420 people with HIV assessed the importance of eight optimal attributes, the acceptability of fifteen minimum attributes, and five prominent cure strategies. Latent class analysis identified groups of people with different patterns of importance ratings.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Optimal HIV cure attributes most frequently endorsed as important were \u2018no HIV transmission risk\u2019 (76.4%), \u2018immune system recovery\u2019 (66.4%), and \u2018protection from reinfection\u2019 (63.8%). Twelve of fifteen minimum attributes and all cure strategies were acceptable (mean\u2009&gt;\u20093). Four latent classes of importance ratings emerged: exacting (\n                      <jats:italic>N<\/jats:italic>\n                      \u2009=\u2009129, 30.7%; all attributes important), ambivalent (\n                      <jats:italic>N<\/jats:italic>\n                      \u2009=\u2009121, 28.8%; neutral ratings), indifferent (\n                      <jats:italic>N<\/jats:italic>\n                      \u2009=\u200928, 6.7%; most attributes unimportant\/neutral), and selective (\n                      <jats:italic>N<\/jats:italic>\n                      \u2009=\u2009142, 35.2%; most attributes important except cure regimen\u2010related factors). ANOVAs showed that participants with ambivalent importance patterns were less accepting of minimum attributes and strategies, while participants with indifferent importance patterns were more accepting of unacceptable minimum attributes.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>People with HIV in the Netherlands find most HIV cure interventions acceptable, even if they do not meet optimal TPPs. However, perspectives differ across subgroups.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/hiv.70165","type":"journal-article","created":{"date-parts":[[2025,12,11]],"date-time":"2025-12-11T03:34:21Z","timestamp":1765424061000},"page":"442-458","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Towards inclusive\n                    <scp>HIV<\/scp>\n                    cure development: Identifying important and acceptable\n                    <scp>HIV<\/scp>\n                    cure attributes and strategies among people with\n                    <scp>HIV<\/scp>\n                    in the Netherlands"],"prefix":"10.1111","volume":"27","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9839-9766","authenticated-orcid":false,"given":"Maaike A. J.","family":"Noorman","sequence":"first","affiliation":[{"name":"Department of Interdisciplinary Social Science Utrecht University  Utrecht The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5895-7935","authenticated-orcid":false,"given":"John B. F.","family":"de Wit","sequence":"additional","affiliation":[{"name":"Department of Interdisciplinary Social Science Utrecht University  Utrecht The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2741-8717","authenticated-orcid":false,"given":"Tamika A.","family":"Marcos","sequence":"additional","affiliation":[{"name":"Department of Work and Social Psychology Maastricht University  Maastricht The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9336-5022","authenticated-orcid":false,"given":"Sarah E.","family":"Stutterheim","sequence":"additional","affiliation":[{"name":"Department of Health Promotion and Care and Public Health Research Institute (CAPHRI) Maastricht University  Maastricht The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thijs","family":"Albers","sequence":"additional","affiliation":[{"name":"Hiv Vereniging  Amsterdam The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6607-1993","authenticated-orcid":false,"given":"Kai J.","family":"Jonas","sequence":"additional","affiliation":[{"name":"Department of Work and Social Psychology Maastricht University  Maastricht The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0955-3691","authenticated-orcid":false,"given":"Chantal","family":"Den Daas","sequence":"additional","affiliation":[{"name":"Health Psychology Group, Institute of Applied Health Sciences University of Aberdeen  Aberdeen UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,12,10]]},"reference":[{"key":"e_1_2_11_2_1","unstructured":"UNAIDS.Fact sheet 2024. 2024. 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