{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,17]],"date-time":"2026-07-17T15:03:32Z","timestamp":1784300612889,"version":"3.55.0"},"reference-count":61,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2026,2,27]],"date-time":"2026-02-27T00:00:00Z","timestamp":1772150400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,2,27]],"date-time":"2026-02-27T00:00:00Z","timestamp":1772150400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["HIV Medicine"],"published-print":{"date-parts":[[2026,6]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>Screening for mental health symptoms is crucial in people with chronic conditions, including individuals with HIV, and recommended indeed by Guidelines. The Generalized Anxiety Disorder\u20107 (GAD\u20107) and Patient Health Questionnaire\u20109 (PHQ\u20109) are validated tools used and endorsed by guidelines to screen for anxiety and depression symptoms. This study aimed to evaluate the prevalence and risk factors for anxiety and depression symptoms and quality of life (QoL) assessment in a cohort living with HIV in an HIV service in Northern Italy.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We performed a cross\u2010sectional analysis in adult people with HIV who completed the screening with the GAD\u20107 and PHQ\u20109 questionnaires, along with a QoL assessment using the Visual Analogue Scale (VAS). People with known mental health disorders, dementia, cognitive impairment, or who were unable to complete the questionnaires were excluded. Moderate\u2010to\u2010severe anxiety and depression symptoms were defined according to standard cut\u2010offs of the GAD\u20107 (\u226510) and PHQ\u20109 (\u226510), respectively. A QoL score\u2009\u2265\u200960 was considered indicative of good well\u2010being. Descriptive statistics and logistic regression analyses were conducted to investigate the associations between mental health symptoms and demographics, clinical and behavioural factors.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      One thousand four hundred and forty\u2010nine people with HIV, were included. Moderate\u2010to\u2010severe anxiety was identified in 14.4% (9.7% moderate, 4.7% severe), and moderate\u2010to\u2010severe depression in 11.9% (8.7% moderate, 3.2% severe). Suicidal ideation over the last 2\u2009weeks was reported in 5.1% of participants, who were referred for immediate psychiatric counselling. In multivariate models, female gender was significantly associated with moderate\u2010to\u2010severe anxiety (aOR: 1.59, 95% CI: 1.09\u20132.31,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.014), whereas Black African ethnicity was a protective factor (aOR: 0.39, 95% CI: 0.17\u20130.82,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.020). Female gender also emerged as a significant risk factor for moderate\u2010to\u2010severe depression (aOR: 1.74, 95% CI: 1.16\u20132.59;\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.006). 1235 (85.2%) participants self\u2010reported having a good quality of life.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Our findings underscore that people with HIV face a substantial burden of anxiety and depression symptoms. Women with HIV appear to be particularly vulnerable to both conditions, whereas Black African ethnicity appears to confer resilience against anxiety. These results highlight the requirement to integrate routine mental health screening into HIV care and tailor\u2010specific interventions to gender and cultural contexts.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/hiv.70211","type":"journal-article","created":{"date-parts":[[2026,3,8]],"date-time":"2026-03-08T16:58:48Z","timestamp":1772989128000},"page":"896-906","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["The outcomes of anxiety and depression symptom screening in a population with\n                    <scp>HIV<\/scp>\n                    : Insights from an\n                    <scp>HIV<\/scp>\n                    service in Northern Italy"],"prefix":"10.1111","volume":"27","author":[{"given":"Peacchaima","family":"Purusothman","sequence":"first","affiliation":[{"name":"Infectious and Tropical Diseases Unit Hospital Tengku Ampuan Rahimah  Klang Malaysia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lorenza","family":"Barbisoni","sequence":"additional","affiliation":[{"name":"Psychiatry Unit Padua University Hospital  Padua Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Davide","family":"Leoni","sequence":"additional","affiliation":[{"name":"Infectious and Tropical Diseases Unit Padua University Hospital, Padua, Italy Project and Clinical Research Unit, Padua University Hospital  Padua Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lolita","family":"Sasset","sequence":"additional","affiliation":[{"name":"Infectious and Tropical Diseases Unit Padua University Hospital, Padua, Italy Project and Clinical Research Unit, Padua University Hospital  Padua Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paolo","family":"D'Angelo","sequence":"additional","affiliation":[{"name":"Psychiatry Unit Padua University Hospital  Padua Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0000-8992-1049","authenticated-orcid":false,"given":"Giacomo","family":"Berti","sequence":"additional","affiliation":[{"name":"Infectious and Tropical Diseases Unit Padua University Hospital, Padua, Italy Project and Clinical Research Unit, Padua University Hospital  Padua Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Angela","family":"Favaro","sequence":"additional","affiliation":[{"name":"Psychiatry Unit Padua University Hospital  Padua Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0263-0703","authenticated-orcid":false,"given":"Maria","family":"Mazzitelli","sequence":"additional","affiliation":[{"name":"Infectious and Tropical Diseases Unit Padua University Hospital, Padua, Italy Project and Clinical Research Unit, Padua University Hospital  Padua Italy"},{"name":"Department of Medical and Surgical Sciences Fondazione Policlinico Universitario Agostino Gemelli IRCCS  Rome Italy"},{"name":"Dipartimento di Sicurezza e Bioetica \u2013 Sezione di Malattie Infettive Universit\u00e0 Cattolica del Sacro Cuore  Rome Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Annamaria","family":"Cattelan","sequence":"additional","affiliation":[{"name":"Infectious and Tropical Diseases Unit Padua University Hospital, Padua, Italy Project and Clinical Research Unit, Padua University Hospital  Padua Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,2,27]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(13)61809-7"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamanetworkopen.2020.7954"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2352-3018(22)00400-3"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/cir627"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.mpmed.2022.02.012"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.immuni.2013.10.001"},{"issue":"1","key":"e_1_2_9_8_1","first-page":"15","article-title":"Chronicity, ageing and multimorbidity","volume":"36","author":"Branas F","year":"2018","journal-title":"Enferm Infecc Microbiol Clin (Engl Ed)"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1080\/09540121.2020.1844864"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1089\/aid.2021.0083"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(21)02143-7"},{"key":"e_1_2_9_12_1","unstructured":"Centers for Disease Control and Prevention.National health statistics reports. Symptoms of anxiety and depression among adults: United States 2019 and 2022. Accessed January 11 2026.https:\/\/www.cdc.gov\/nchs\/data\/nhsr\/nhsr213.pdf"},{"key":"e_1_2_9_13_1","doi-asserted-by":"publisher","DOI":"10.1080\/13548506.2024.2424998"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.3390\/healthcare13010085"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10461-006-9099-1"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuint.2011.06.011"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopsych.2008.11.029"},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmjopen-2016-011453"},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12981-025-00827-4"},{"key":"e_1_2_9_20_1","doi-asserted-by":"publisher","DOI":"10.1097\/QAI.0B013E31822D490A"},{"key":"e_1_2_9_21_1","doi-asserted-by":"publisher","DOI":"10.1155\/2023\/7665247"},{"key":"e_1_2_9_22_1","unstructured":"European AIDS Clinical Society.EACS guidelines version 13.0. Accessed January 11 2026.https:\/\/eacs.sanfordguide.com\/"},{"key":"e_1_2_9_23_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1525-1497.2001.016009606.x"},{"key":"e_1_2_9_24_1","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.166.10.1092"},{"key":"e_1_2_9_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.genhosppsych.2015.11.005"},{"key":"e_1_2_9_26_1","first-page":"15","article-title":"Measurement of subjective phenomena in primary care research: the visual analogue scale","volume":"13","author":"Miller MD","year":"1993","journal-title":"Fam Pract Res J"},{"key":"e_1_2_9_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/0168-8510(90)90421-9"},{"key":"e_1_2_9_28_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11136-025-03947-6"},{"key":"e_1_2_9_29_1","doi-asserted-by":"publisher","DOI":"10.3390\/encyclopedia5040190"},{"key":"e_1_2_9_30_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.eimc.2022.07.012"},{"key":"e_1_2_9_31_1","doi-asserted-by":"publisher","DOI":"10.1177\/0956462417750708"},{"key":"e_1_2_9_32_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmjph-2024-002114"},{"key":"e_1_2_9_33_1","doi-asserted-by":"publisher","DOI":"10.1111\/hiv.13296"},{"key":"e_1_2_9_34_1","doi-asserted-by":"publisher","DOI":"10.2174\/0118746136250239231025074541"},{"key":"e_1_2_9_35_1","doi-asserted-by":"publisher","DOI":"10.52872\/001c.38649"},{"key":"e_1_2_9_36_1","doi-asserted-by":"publisher","DOI":"10.2174\/1745017902016010059"},{"key":"e_1_2_9_37_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.yfrne.2014.05.004"},{"key":"e_1_2_9_38_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0176256"},{"key":"e_1_2_9_39_1","doi-asserted-by":"publisher","DOI":"10.7448\/IAS.18.6.20302"},{"key":"e_1_2_9_40_1","doi-asserted-by":"publisher","DOI":"10.1111\/hiv.12398"},{"key":"e_1_2_9_41_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10461-021-03373-y"},{"key":"e_1_2_9_42_1","doi-asserted-by":"publisher","DOI":"10.2147\/JMDH.S410538"},{"key":"e_1_2_9_43_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pmen.0000035"},{"key":"e_1_2_9_44_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0077230"},{"key":"e_1_2_9_45_1","doi-asserted-by":"publisher","DOI":"10.1097\/PSY.0000000000001127"},{"key":"e_1_2_9_46_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jad.2024.05.036"},{"key":"e_1_2_9_47_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13104-024-07076-0"},{"key":"e_1_2_9_48_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2458-12-926"},{"key":"e_1_2_9_49_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10461-024-04571-0"},{"key":"e_1_2_9_50_1","doi-asserted-by":"publisher","DOI":"10.5498\/wjp.v6.i1.128"},{"key":"e_1_2_9_51_1","doi-asserted-by":"publisher","DOI":"10.3389\/fpsyt.2025.1507020"},{"key":"e_1_2_9_52_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12529-020-09951-z"},{"key":"e_1_2_9_53_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmjopen-2023-077015"},{"key":"e_1_2_9_54_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0189207"},{"key":"e_1_2_9_55_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12955-021-01670-7"},{"key":"e_1_2_9_56_1","doi-asserted-by":"publisher","DOI":"10.4102\/sajp.v79i1.1921"},{"key":"e_1_2_9_57_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2352-3018(14)70018-9"},{"key":"e_1_2_9_58_1","article-title":"Evaluation of quality of life, anxiety and depression in people living with HIV","volume":"13","author":"\u015eahino\u011flu MS","year":"2024","journal-title":"Mediterr J Infect Microb Antimicrob Agents"},{"key":"e_1_2_9_59_1","doi-asserted-by":"publisher","DOI":"10.1080\/09540121.2016.1146209"},{"key":"e_1_2_9_60_1","doi-asserted-by":"publisher","DOI":"10.4103\/2249-4863.222016"},{"key":"e_1_2_9_61_1","doi-asserted-by":"publisher","DOI":"10.1377\/hlthaff.27.2.393"},{"key":"e_1_2_9_62_1","doi-asserted-by":"publisher","DOI":"10.1080\/09540120802511877"}],"container-title":["HIV Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/hiv.70211","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/hiv.70211","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/hiv.70211","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,17]],"date-time":"2026-07-17T14:12:31Z","timestamp":1784297551000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/hiv.70211"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,2,27]]},"references-count":61,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2026,6]]}},"alternative-id":["10.1111\/hiv.70211"],"URL":"https:\/\/doi.org\/10.1111\/hiv.70211","archive":["Portico"],"relation":{},"ISSN":["1464-2662","1468-1293"],"issn-type":[{"value":"1464-2662","type":"print"},{"value":"1468-1293","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,2,27]]},"assertion":[{"value":"2025-11-10","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-02-10","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-02-27","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}