{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,21]],"date-time":"2026-10-21T21:37:52Z","timestamp":1792618672837,"version":"4.5.0"},"reference-count":54,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2026,4,8]],"date-time":"2026-04-08T00:00:00Z","timestamp":1775606400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,4,8]],"date-time":"2026-04-08T00:00:00Z","timestamp":1775606400000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100004586","name":"Funda\u00e7\u00e3o Carlos Chagas Filho de Amparo \u00e0 Pesquisa do Estado do Rio de Janeiro","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004586","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100006507","name":"Funda\u00e7\u00e3o Oswaldo Cruz","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100006507","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002322","name":"Coordena\u00e7\u00e3o de Aperfei\u00e7oamento de Pessoal de N\u00edvel Superior","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002322","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003593","name":"Conselho Nacional de Desenvolvimento Cient\u00edfico e Tecnol\u00f3gico","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003593","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["HIV Medicine"],"published-print":{"date-parts":[[2026,8]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>People living with HIV (PLWH) face an increasing burden of non\u2010AIDS\u2010related chronic conditions. However, how the COVID\u201019 pandemic affected chronic disease\u2010related mortality in this population remains unclear. We assessed changes in mortality among PLWH in Brazil during the COVID\u201019 pandemic.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We conducted a nationwide analysis using Brazil's Mortality Information System, including adults aged \u226518\u2009years with and without HIV mentioned on death certificates from 2016 to 2022. Age\u2010 and sex\u2010adjusted mortality ratios (aMRs) were estimated for all\u2010cause mortality and for deaths associated with diabetes mellitus (DM), hypertension (HTN) and cardiovascular disease (CVD) using Poisson generalized linear mixed models, with the pre\u2010pandemic period 2016\u20132019 used as the reference.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Between 2016 and 2022, 90\u2009888 deaths occurred among PLWH and 9\u2009723\u2009490 among individuals without HIV. Among PLWH, adjusted all\u2010cause mortality ratios were lower in 2020 (aMR 0.918; 95% CI 0.900\u20130.936) and 2022 (aMR 0.950; 95% CI 0.932\u20130.968), while estimates for 2021 were close to the reference period. In contrast, individuals without HIV experienced increased mortality in 2020 (aMR 1.106; 95% CI 1.104\u20131.108), 2021 (aMR 1.269; 95% CI 1.267\u20131.272) and 2022 (aMR 1.029; 95% CI 1.027\u20131.031). Among PLWH, mortality associated with DM (aMRs 1.573\u20131.666), HTN (aMRs 1.738\u20131.978) and CVD (aMRs 1.242\u20131.377) increased consistently across all pandemic years. Among individuals without HIV, chronic disease\u2010related mortality showed greater temporal variability, with increases in 2020 and 2021 followed by reductions in 2022.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Chronic disease\u2010related mortality increased persistently among PLWH during the COVID\u201019 pandemic, contrasting with declining trends in the general population. These results emphasize distinct mortality dynamics among PLWH during public health crises.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/hiv.70240","type":"journal-article","created":{"date-parts":[[2026,4,8]],"date-time":"2026-04-08T09:05:10Z","timestamp":1775639110000},"page":"1265-1276","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Mortality trends for diabetes mellitus, hypertension and cardiovascular disease among people living with and without\n                    <scp>HIV<\/scp>\n                    in Brazil during the\n                    <scp>COVID<\/scp>\n                    \u201019 pandemic, 2020\u20132022"],"prefix":"10.1111","volume":"27","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4781-3952","authenticated-orcid":false,"given":"Tatyellen Natasha","family":"da Costa Oliveira","sequence":"first","affiliation":[{"name":"Escola Nacional de Sa\u00fade P\u00fablica Sergio Arouca, Funda\u00e7\u00e3o Oswaldo Cruz  Rio de Janeiro Brazil"},{"name":"Se\u00e7\u00e3o de Ensino e Informa\u00e7\u00e3o Cient\u00edfica Instituto Evandro Chagas  Ananindeua Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rodrigo C.","family":"Moreira","sequence":"additional","affiliation":[{"name":"Instituto Nacional de Infectologia Evandro Chagas Funda\u00e7\u00e3o Oswaldo Cruz  Rio de Janeiro Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luiz Max","family":"Carvalho","sequence":"additional","affiliation":[{"name":"Funda\u00e7\u00e3o Get\u00falio Vargas  Rio de Janeiro Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fl\u00e1vio Code\u00e7o","family":"Coelho","sequence":"additional","affiliation":[{"name":"Funda\u00e7\u00e3o Get\u00falio Vargas  Rio de Janeiro Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marcelo Ferreira","family":"da Costa Gomes","sequence":"additional","affiliation":[{"name":"Programa de Computa\u00e7\u00e3o Cient\u00edfica Funda\u00e7\u00e3o Oswaldo Cruz  Rio de Janeiro Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leonardo S.","family":"Bastos","sequence":"additional","affiliation":[{"name":"Programa de Computa\u00e7\u00e3o Cient\u00edfica Funda\u00e7\u00e3o Oswaldo Cruz  Rio de Janeiro Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"La\u00eds","family":"Picinini Freitas","sequence":"additional","affiliation":[{"name":"Departamento de Epidemiologia e M\u00e9todos Quantitativos em Sa\u00fade Vice Dire\u00e7\u00e3o de Pesquisa e Inova\u00e7\u00e3o Escola Nacional de Sa\u00fade P\u00fablica Sergio Arouca, Funda\u00e7\u00e3o Oswaldo Cruz  Rio de Janeiro Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antonio G.","family":"Pacheco","sequence":"additional","affiliation":[{"name":"Programa de Computa\u00e7\u00e3o Cient\u00edfica 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