{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,21]],"date-time":"2026-10-21T21:37:53Z","timestamp":1792618673971,"version":"4.5.0"},"reference-count":39,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2026,5,17]],"date-time":"2026-05-17T00:00:00Z","timestamp":1778976000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2026,5,17]],"date-time":"2026-05-17T00:00:00Z","timestamp":1778976000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100004587","name":"Instituto de Salud Carlos III","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004587","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["HIV Medicine"],"published-print":{"date-parts":[[2026,8]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>Lymphomas remain among the most frequent HIV\u2010associated malignancies, with risk persisting despite effective virological control.<\/jats:p>\n                    <jats:p>This study describes the clinical, epidemiological and prognostic characteristics of lymphomas (both Hodgkin [HL] and non\u2010Hodgkin [NHL]) in people living with HIV (PLWH), according to virological suppression at diagnosis and assesses lymphoma\u2010related mortality at 1\u2009year and overall survival at 5\u2009years.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We conducted a multicentre retrospective study including PLWH from the Spanish CoRIS cohort, who were diagnosed with lymphoma between 2004 and 2022 and had HIV viral load data at diagnosis. Virological suppression was defined as HIV\u20101 RNA &lt;100 copies\/mL within the 6 months prior to and 1 month following lymphoma diagnosis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Among 18\u2009573 PLWH included in CoRIS, 291 developed lymphoma, with virological data available for 245 individuals, of whom 49 (20%) had virological suppression. People with detectable HIV viral load had lower CD4 counts (median 180 cells\/mm\n                      <jats:sup>3<\/jats:sup>\n                      [IQR 80\u2013330] vs. 371 cells\/mm\n                      <jats:sup>3<\/jats:sup>\n                      [IQR 202\u2013583],\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.001) and more advanced Ann Arbor stage (stage III\u2013IV: 82.0% vs. 64.1%,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.027) compared with those with virological suppression. Despite this, they showed similar treatment response (complete remission: 67.1% vs. 76.2%) and relapse rates (16.3% vs. 18.4%,\n                      <jats:italic>p<\/jats:italic>\n                      \u2009=\u20090.779). Furthermore, virological suppression was not independently associated with 1\u2010year lymphoma\u2010specific or 5\u2010year overall survival.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>In PLWH diagnosed with lymphoma, prognosis is independent of HIV virological status at diagnosis. These findings support that lymphoma management in PLWH should be guided by standard oncological criteria, alongside antiretroviral therapy, regardless of HIV viral suppression status.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/hiv.70257","type":"journal-article","created":{"date-parts":[[2026,5,18]],"date-time":"2026-05-18T05:56:30Z","timestamp":1779083790000},"page":"1312-1332","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Hodgkin and non\u2010Hodgkin lymphomas in the post\u2010antiretroviral therapy era according to\n                    <scp>HIV<\/scp>\n                    virological suppression"],"prefix":"10.1111","volume":"27","author":[{"given":"Teresa","family":"Ald\u00e1miz\u2010Echevarria","sequence":"first","affiliation":[{"name":"Servicio de Microbiolog\u00eda Cl\u00ednica y Enfermedades Infecciosas Gregorio Mara\u00f1\u00f3n General University Hospital  Madrid Spain"},{"name":"Instituto de Investigaci\u00f3n Sanitaria Gregorio Mara\u00f1\u00f3n (IiSGM)  Madrid Spain"},{"name":"CIBERINFEC, ISCIII \u2013 CIBER de Enfermedades Infecciosas Instituto de Salud Carlos III  Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francisco","family":"Tejerina","sequence":"additional","affiliation":[{"name":"Servicio de Microbiolog\u00eda Cl\u00ednica y Enfermedades Infecciosas Gregorio Mara\u00f1\u00f3n General University Hospital  Madrid Spain"},{"name":"Instituto de Investigaci\u00f3n Sanitaria Gregorio Mara\u00f1\u00f3n (IiSGM)  Madrid Spain"},{"name":"CIBERINFEC, ISCIII \u2013 CIBER de Enfermedades Infecciosas Instituto de Salud Carlos III  Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chiara","family":"Fanciulli","sequence":"additional","affiliation":[{"name":"Servicio de Microbiolog\u00eda Cl\u00ednica y Enfermedades Infecciosas Gregorio Mara\u00f1\u00f3n General University Hospital  Madrid Spain"},{"name":"Instituto de Investigaci\u00f3n Sanitaria Gregorio Mara\u00f1\u00f3n (IiSGM)  Madrid Spain"},{"name":"CIBERINFEC, ISCIII \u2013 CIBER de Enfermedades Infecciosas Instituto de Salud Carlos III  Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cristina","family":"Diez","sequence":"additional","affiliation":[{"name":"Servicio de Microbiolog\u00eda Cl\u00ednica y Enfermedades Infecciosas Gregorio Mara\u00f1\u00f3n General University Hospital  Madrid Spain"},{"name":"Instituto de Investigaci\u00f3n Sanitaria Gregorio Mara\u00f1\u00f3n (IiSGM)  Madrid Spain"},{"name":"CIBERINFEC, ISCIII \u2013 CIBER de Enfermedades Infecciosas Instituto de Salud Carlos III  Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leire","family":"Perez","sequence":"additional","affiliation":[{"name":"Servicio de Microbiolog\u00eda Cl\u00ednica y Enfermedades Infecciosas Gregorio Mara\u00f1\u00f3n General University Hospital  Madrid Spain"},{"name":"Instituto de Investigaci\u00f3n Sanitaria Gregorio Mara\u00f1\u00f3n (IiSGM)  Madrid Spain"},{"name":"CIBERINFEC, ISCIII \u2013 CIBER de Enfermedades Infecciosas Instituto de Salud Carlos III  Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jos\u00e9 Maria","family":"Bell\u00f3n","sequence":"additional","affiliation":[{"name":"Instituto de Investigaci\u00f3n Sanitaria Gregorio Mara\u00f1\u00f3n (IiSGM)  Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nuria","family":"Espinosa","sequence":"additional","affiliation":[{"name":"Unidad cl\u00ednica de Enfermedades Infecciosas, microbiolog\u00eda y parasitolog\u00edas (UCEIMP) Hospital Universitario Virgen del Roci)  Sevilla Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Santiago Moreno","family":"Guill\u00e9n","sequence":"additional","affiliation":[{"name":"Head Department of Infectious Diseases Jefe de Servicio de Enfermedades Infecciosas  Madrid Spain"},{"name":"Medicine Hospital Universitario Ram\u00f3n y Cajal University Hospital Ram\u00f3n y Cajal Universidad de Alcal\u00e1\/Alcal\u00e1 University  Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9961-5544","authenticated-orcid":false,"given":"Maria","family":"del Mar Arcos\u2010Rueda","sequence":"additional","affiliation":[{"name":"HIV Unit. 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