{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,2]],"date-time":"2026-10-02T07:58:09Z","timestamp":1790927889274,"version":"4.1.0"},"reference-count":21,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2026,7,8]],"date-time":"2026-07-08T00:00:00Z","timestamp":1783468800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,7,8]],"date-time":"2026-07-08T00:00:00Z","timestamp":1783468800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["HIV Medicine"],"published-print":{"date-parts":[[2026,10]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Data on chemotherapeutic efficacy and tolerability for Kaposi Sarcomas (KS) in people living with HIV (PWH) and HIV\u2010virological control are limited. We aimed to describe clinical responses and tolerability of KS therapies in PWH with HIV\u2010aviraemic KS in a prospective cohort.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We analysed all PWH with active KS with an HIV plasma viral load &lt;200 copies\/mL for more than 12\u2009months under combination antiretroviral therapy (cART), whose clinical conditions were presented between the 1st of June 2021 and the 2nd of January 2023 to a national French Cancer HIV network panel. Clinicians completed a standardized questionnaire to assess KS history and standardized treatment response.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>We included 18 PLHIV (94% male, median age 49\u2009years). The median CD4 count was 614\/mm3 and the median CD4\/CD8 ratio was 0.8. Fifteen had already experienced relapses of KS. Median follow\u2010up time was 30.1\u2009months (IQR [24 to 34.2]). We observed seven well\u2010controlled PWH with no KS relapse after a median follow\u2010up of 16\u2009months (IQR 9.5 to 22.5), eight well\u2010controlled PWH who experienced KS relapse after a median of 6\u2009months (IQR, 3\u201312) following chemotherapy, primarily limited to the skin, and two PWH with visceral KS relapse in a context of non\u2010adherence. PWH who relapsed\/progressed were older and had a longer duration of HIV virological control.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>KS in PWH with virological control respond to chemotherapy, but are prone to relapses, primarily to the skin, and strategies can be limited by past and cumulative toxicities. Older age and longer duration of virological control may negatively impact the probability of KS response.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/hiv.70280","type":"journal-article","created":{"date-parts":[[2026,7,8]],"date-time":"2026-07-08T12:39:37Z","timestamp":1783514377000},"page":"1715-1721","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Outcomes of Kaposi sarcoma in people living with\n                    <scp>HIV<\/scp>\n                    who maintain long\u2010term viral suppression: A prospective case\u2010series"],"prefix":"10.1111","volume":"27","author":[{"ORCID":"https:\/\/orcid.org\/0009-0002-0148-6332","authenticated-orcid":false,"given":"S.","family":"Bacquart","sequence":"first","affiliation":[{"name":"CHU Montpellier, INSERM U 1175, 191 avenue du Doyen Gaston Giraud  Montpellier France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0047-0101","authenticated-orcid":false,"given":"R.","family":"Palich","sequence":"additional","affiliation":[{"name":"Piti\u00e9 Salpetri\u00e8re AP\u2010HP, NSERM U1136, 27 rue Chaligny  Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7020-8160","authenticated-orcid":false,"given":"M.","family":"Veyri","sequence":"additional","affiliation":[{"name":"Piti\u00e9 Salp\u00eatri\u00e8re, AP\u2010HP Institut Universitaire de Canc\u00e9rologie, INSERM U1136  Paris France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.","family":"Bregigeon\u2010Ronot","sequence":"additional","affiliation":[{"name":"Service d'Immuno\u2010h\u00e9matologie Clinique AP\u2010HM, INSERM, H\u00f4pital Sainte\u2010Marguerite Universit\u00e9 Aix Marseille, 270 boulevard de St Marguerite  Marseille France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.\u2010C.","family":"Picot","sequence":"additional","affiliation":[{"name":"CHU de Montpellier Unit\u00e9 de Recherche Clinique and \u00c9pid\u00e9miologie  Montpellier France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C.","family":"Vidal","sequence":"additional","affiliation":[{"name":"CHU de Montpellier Unit\u00e9 de Recherche Clinique and \u00c9pid\u00e9miologie  Montpellier France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L.","family":"Galicier","sequence":"additional","affiliation":[{"name":"H\u00f4pital La Timone, M\u00e9decine Interne, APHM, Universit\u00e9 Aix Marseille  Marseille France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.","family":"Choquet","sequence":"additional","affiliation":[{"name":"H\u00e9matologie, APHP Piti\u00e9\u2010Salp\u00eatri\u00e8re, 47 boulevard de l'h\u00f4pital  Paris 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