{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,2]],"date-time":"2026-10-02T06:55:44Z","timestamp":1790924144716,"version":"4.1.0"},"reference-count":49,"publisher":"Wiley","license":[{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100010474","name":"Swiss HIV Cohort Research Foundation","doi-asserted-by":"publisher","award":["821"],"award-info":[{"award-number":["821"]}],"id":[{"id":"10.13039\/501100010474","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["HIV Medicine"],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Despite high risk of HIV infection, uptake of pre\u2010exposure prophylaxis (PrEP) remains limited among male and transgender sex workers (MSW and TSW), and data on tailored interventions to improve access are scarce. The Nightcaf\u00e9 programme addresses this gap by offering low\u2010threshold PrEP provision in a community\u2010centred setting. This study assessed the programme's uptake, clinical feasibility and subsequent engagement in PrEP care.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Eligible MSW and TSW visiting the Nightcaf\u00e9, a social space for sex workers, were offered same\u2010night oral PrEP after a non\u2010reactive HIV rapid test. Follow\u2010ups were scheduled at 4\u2009weeks and then quarterly at Checkpoint Zurich. We described participants' HIV exposure, baseline clinical findings, same\u2010night PrEP provision and participants' stated intention to initiate PrEP and attendance at follow\u2010up care.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Between January 2022 and December 2023, 99 participants enrolled in the programme; 57 agreed to share their data for research. Participants demonstrated substantial clinical indications for PrEP: 77% (\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u200944) reported inconsistent condom use with a median of 20 sexual partners in the previous 3 months. No baseline clinical findings requiring deferral of PrEP initiation were identified. All expressed intent to initiate PrEP. Among participants not already enrolled in PrEP programmes abroad, 80% (95% CI: 70%\u201387%,\n                      <jats:italic>n<\/jats:italic>\n                      \u2009=\u200970) completed at least one follow\u2010up. No known subsequent HIV seroconversions occurred.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Community\u2010based same\u2010night PrEP provision was clinically feasible and resulted in high initial linkage to facility\u2010based follow\u2010up care among MSW and TSW. Longer\u2010term follow\u2010up and comparative studies are needed to determine whether this model improves sustained retention in PrEP care.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/hiv.70313","type":"journal-article","created":{"date-parts":[[2026,10,2]],"date-time":"2026-10-02T06:49:32Z","timestamp":1790923772000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Same\u2010night\n                    <scp>PrEP<\/scp>\n                    in community care: The Nightcaf\u00e9 model for male and transgender sex workers"],"prefix":"10.1111","author":[{"ORCID":"https:\/\/orcid.org\/0009-0005-4257-4445","authenticated-orcid":false,"given":"Elena","family":"Heizmann","sequence":"first","affiliation":[{"name":"Checkpoint Zurich  Zurich 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