{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,12]],"date-time":"2026-10-12T05:45:42Z","timestamp":1791783942074,"version":"4.3.4"},"reference-count":28,"publisher":"Wiley","license":[{"start":{"date-parts":[[2026,10,11]],"date-time":"2026-10-11T00:00:00Z","timestamp":1791676800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2026,10,11]],"date-time":"2026-10-11T00:00:00Z","timestamp":1791676800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100009023","name":"Precursory Research for Embryonic Science and Technology","doi-asserted-by":"publisher","award":["JPMJPR23R1"],"award-info":[{"award-number":["JPMJPR23R1"]}],"id":[{"id":"10.13039\/501100009023","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["HIV Medicine"],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>To compare objectively measured cardiometabolic health between people living with HIV (PLWH) and individuals without HIV using nationwide health checkup data linked to administrative claims, thereby partially mitigating surveillance bias associated with routine HIV care.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We conducted a cross\u2010sectional matched analysis using the JMDC database, which links administrative claims with annual health checkup data. Men with HIV receiving antiretroviral therapy (ART) and men without HIV who underwent health checkups between 2017 and 2023 were included. PLWH were exact\u2010matched 1:5 to individuals without HIV by age and calendar year. Cardiometabolic outcomes included hypertension, diabetes mellitus, dyslipidaemia and BMI, defined using treatment information and objectively measured clinical parameters. Conditional logistic regression and matched\u2010set fixed\u2010effects linear regression were used.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      We included 2596 PLWH and 12\u2009980 matched individuals without HIV (median age 45.0\u2009years [IQR 37.0\u201351.0]). PLWH were more likely to receive treatment for hypertension, diabetes mellitus and dyslipidaemia, whereas measured systolic blood pressure, HbA1c and LDL\u2010C were comparable to or lower than those in individuals without HIV. HIV infection was not independently associated with hypertension (aOR 0.95, 95% CI 0.82\u20131.09) or diabetes mellitus (aOR 1.00, 0.82\u20131.22) but was associated with dyslipidaemia (aOR 1.22, 1.08\u20131.39) and slightly higher BMI (adjusted mean difference 0.28\u2009kg\/m\n                      <jats:sup>2<\/jats:sup>\n                      , 0.02\u20130.55).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Among men receiving contemporary HIV care in Japan, HIV infection was associated with modest differences in BMI and dyslipidaemia but not with hypertension or diabetes mellitus.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/hiv.70317","type":"journal-article","created":{"date-parts":[[2026,10,12]],"date-time":"2026-10-12T05:04:59Z","timestamp":1791781499000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["A cross\u2010sectional analysis of cardiometabolic and lifestyle\u2010related profiles in men living with\n                    <scp>HIV<\/scp>\n                    in Japan using linked nationwide claims and health checkup data"],"prefix":"10.1111","author":[{"given":"Kohei","family":"Yamashita","sequence":"first","affiliation":[{"name":"Department of Infectious Diseases, Graduate School of Medicine The University of Tokyo  Bunkyo\u2010ku Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1677-3369","authenticated-orcid":false,"given":"Kazuhiko","family":"Ikeuchi","sequence":"additional","affiliation":[{"name":"Department of Infectious Diseases, Graduate School of Medicine The University of Tokyo  Bunkyo\u2010ku Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1292-1707","authenticated-orcid":false,"given":"Ryoko","family":"Sekiya","sequence":"additional","affiliation":[{"name":"Department of Infectious Diseases Tokyo Metropolitan Cancer and Infectious Diseases Center Komagome Hospital  Bunkyo\u2010ku Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuki","family":"Arisato","sequence":"additional","affiliation":[{"name":"Department of Infectious Diseases, Graduate School of Medicine The University of Tokyo  Bunkyo\u2010ku Japan"},{"name":"Department of Infectious Diseases Tokyo Metropolitan Cancer and Infectious Diseases Center Komagome Hospital  Bunkyo\u2010ku 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Tokyo  Minato\u2010ku Japan"},{"name":"Japan Institute for Health Security  Shinjuku\u2010ku Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0851-1887","authenticated-orcid":false,"given":"Takeya","family":"Tsutsumi","sequence":"additional","affiliation":[{"name":"Department of Infectious Diseases, Graduate School of Medicine The University of Tokyo  Bunkyo\u2010ku Japan"},{"name":"Department of Infection Control and Prevention, Graduate School of Medicine The University of Tokyo  Bunkyo\u2010ku Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,10,11]]},"reference":[{"key":"e_1_2_10_2_1","unstructured":"UNAIDS.Global HIV & AIDS statistics \u2014 2025 fact sheet 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