{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,19]],"date-time":"2026-10-19T03:41:48Z","timestamp":1792381308989,"version":"4.4.0"},"reference-count":14,"publisher":"Wiley","license":[{"start":{"date-parts":[[2026,10,18]],"date-time":"2026-10-18T00:00:00Z","timestamp":1792281600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2026,10,18]],"date-time":"2026-10-18T00:00:00Z","timestamp":1792281600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["HIV Medicine"],"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>Real\u2010world implementation of large language models such as ChatGPT to enhance patient education remains limited. We evaluated the feasibility, acceptability and attitudes towards a ChatGPT\u2010based counselling tool among patients and healthcare workers (HCWs) in a specialist infectious diseases clinic.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We conducted a prospective clinical implementation study in a specialist HIV and sexual health clinic in Singapore from Jan 2025 to December 2025. Patients interacted with a custom ChatGPT\u2010based chatbot prior to routine counselling by physicians or pharmacists. Responses were reviewed with patients subsequently during consultation. Post\u2010interaction, patients and HCWs completed structured surveys incorporating domains from a validated survey tool: perceived risk, anxiety, technology\/social influence and intention for future use.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>The chatbot was most frequently used for counselling on antiretroviral therapy initiation or switching, and sexual health advice. A total of 35 patients and 35 HCW assessments were analysed. Patients had greater perceived risk with the use of the chatbot compared to HCWs, as indicated by lower median scores (13, IQR 10\u201316; vs. 18, IQR 15\u201321), while anxiety scores were similar. Technology\/social influence scores were high across both groups (overall median 20, IQR 19\u201322). Most participants indicated willingness for future use. Qualitative feedback highlighted improved patient understanding and more focused consultations, but concerns included lack of contextual nuance and occasional inaccuracies.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>The pilot implementation of a ChatGPT\u2010based counselling tool in a specialist HIV and sexual health clinic was feasible and generally acceptable to patients and HCWs. Further studies are required to evaluate accuracy and clinical effectiveness before broader implementation.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/hiv.70323","type":"journal-article","created":{"date-parts":[[2026,10,19]],"date-time":"2026-10-19T03:26:33Z","timestamp":1792380393000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Pilot study of a\n                    <scp>ChatGPT<\/scp>\n                    \u2010based educational and counselling tool in a specialist\n                    <scp>HIV<\/scp>\n                    and sexual health clinic"],"prefix":"10.1111","author":[{"ORCID":"https:\/\/orcid.org\/0009-0002-7374-8207","authenticated-orcid":false,"given":"Matthew Chung Yi","family":"Koh","sequence":"first","affiliation":[{"name":"Division of Infectious Diseases, Department of Medicine National University Hospital, National University Health System  Singapore Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3339-7281","authenticated-orcid":false,"given":"Jinghao Nicholas","family":"Ngiam","sequence":"additional","affiliation":[{"name":"Division of Infectious Diseases, Department of Medicine National University Hospital, National University Health System  Singapore Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hui Yan Joy","family":"Yong","sequence":"additional","affiliation":[{"name":"Department of Pharmacy National University Hospital, National University Health System  Singapore Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tiffany","family":"Puspita","sequence":"additional","affiliation":[{"name":"Department of Pharmacy National University Hospital, National University Health System  Singapore Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joan","family":"Quah","sequence":"additional","affiliation":[{"name":"Department of Pharmacy National University Hospital, National University Health System  Singapore Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lucinda","family":"Mak","sequence":"additional","affiliation":[{"name":"Department of Pharmacy National University Hospital, National University Health System  Singapore Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hui Wen","family":"Ho","sequence":"additional","affiliation":[{"name":"Department of Pharmacy National University Hospital, National University Health System  Singapore Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Siok Ching","family":"Chia","sequence":"additional","affiliation":[{"name":"Division of Infectious Diseases, Department of Medicine National University Hospital, National University Health System  Singapore Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Timothy","family":"Chia","sequence":"additional","affiliation":[{"name":"Division of Infectious Diseases, Department of Medicine National University Hospital, National University Health System  Singapore Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9614-0662","authenticated-orcid":false,"given":"Priscillia","family":"Lye","sequence":"additional","affiliation":[{"name":"Division of Infectious Diseases, Department of Medicine National University Hospital, National University Health System  Singapore Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4707-0535","authenticated-orcid":false,"given":"Sean","family":"Wu","sequence":"additional","affiliation":[{"name":"Division of Infectious Diseases, Department of Medicine National University Hospital, National University Health System  Singapore Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sai Meng","family":"Tham","sequence":"additional","affiliation":[{"name":"Division of Infectious Diseases, Department of Medicine National University Hospital, National University Health System  Singapore Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8821-6206","authenticated-orcid":false,"given":"Brenda Mae Alferez","family":"Salada","sequence":"additional","affiliation":[{"name":"Division of Infectious Diseases, Department of Medicine National University Hospital, National University Health System  Singapore Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nares","family":"Smitasin","sequence":"additional","affiliation":[{"name":"Division of Infectious Diseases, Department of Medicine National University Hospital, National University Health System  Singapore Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dariusz Piotr","family":"Olszyna","sequence":"additional","affiliation":[{"name":"Division of Infectious Diseases, Department of Medicine National University Hospital, National University Health System  Singapore Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sophia","family":"Archuleta","sequence":"additional","affiliation":[{"name":"Division of Infectious Diseases, Department of Medicine National University Hospital, National University Health System  Singapore Singapore"},{"name":"Yong Loo Lin School of Medicine National University of Singapore  Singapore Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,10,18]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1093\/jtm\/taad124"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/tid.14222"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.nedt.2024.106121"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.2196\/78621"},{"key":"e_1_2_11_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/hiv.13604"},{"key":"e_1_2_11_7_1","doi-asserted-by":"publisher","DOI":"10.1136\/sextrans\u20102024\u2010056217"},{"key":"e_1_2_11_8_1","doi-asserted-by":"publisher","DOI":"10.1093\/jtm\/taae099"},{"key":"e_1_2_11_9_1","doi-asserted-by":"publisher","DOI":"10.2196\/48254"},{"key":"e_1_2_11_10_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmjment\u20102023\u2010300884"},{"key":"e_1_2_11_11_1","doi-asserted-by":"publisher","DOI":"10.2196\/48009"},{"key":"e_1_2_11_12_1","doi-asserted-by":"publisher","DOI":"10.3389\/frai.2023.1169595"},{"key":"e_1_2_11_13_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11904\u2010023\u201000681\u2010x"},{"key":"e_1_2_11_14_1","doi-asserted-by":"publisher","DOI":"10.5588\/ijtld.25.0086"},{"key":"e_1_2_11_15_1","doi-asserted-by":"publisher","DOI":"10.7189\/jogh.15.04192"}],"container-title":["HIV 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