{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,17]],"date-time":"2026-06-17T10:04:30Z","timestamp":1781690670985,"version":"3.54.5"},"reference-count":42,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2015,6,1]],"date-time":"2015-06-01T00:00:00Z","timestamp":1433116800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2015,6,1]],"date-time":"2015-06-01T00:00:00Z","timestamp":1433116800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2016,12,15]],"date-time":"2016-12-15T00:00:00Z","timestamp":1481760000000},"content-version":"vor","delay-in-days":563,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","hpbonline.org","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["HPB"],"published-print":{"date-parts":[[2015,6]]},"DOI":"10.1111\/hpb.12387","type":"journal-article","created":{"date-parts":[[2015,2,28]],"date-time":"2015-02-28T08:43:22Z","timestamp":1425113002000},"page":"502-507","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":17,"title":["Oestrogen hormone receptors in focal nodular hyperplasia"],"prefix":"10.1016","volume":"17","author":[{"given":"Manju D.","family":"Chandrasegaram","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ali","family":"Shah","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John W.","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrew","family":"Ruszkiewicz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David S.","family":"Astill","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Georgina","family":"England","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ravish S.","family":"Raju","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eu Ling","family":"Neo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul M.","family":"Dolan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chuan Ping","family":"Tan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mark","family":"Brooke\u2010Smith","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tom","family":"Wilson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert T.A.","family":"Padbury","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christopher S.","family":"Worthley","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1111\/hpb.12387_bb0010","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1159\/000268404","article-title":"Focal nodular hyperplasia and hepatic adenoma: epidemiology and pathology","volume":"27","author":"Mailette De Buy Wenniger","year":"2010","journal-title":"Dig Surg"},{"key":"10.1111\/hpb.12387_bb0015","doi-asserted-by":"crossref","first-page":"891","DOI":"10.1002\/hep.510260414","article-title":"Evidence of the polyclonal nature of focal nodular hyperplasia of the liver by the study of X\u2010chromosome inactivation","volume":"26","author":"Paradis","year":"1997","journal-title":"Hepatology"},{"key":"10.1111\/hpb.12387_bb0020","doi-asserted-by":"crossref","first-page":"1194","DOI":"10.1002\/hep.1840050622","article-title":"On the pathogenesis of focal nodular hyperplasia of the liver","volume":"5","author":"Wanless","year":"1985","journal-title":"Hepatology"},{"key":"10.1111\/hpb.12387_bb0025","doi-asserted-by":"crossref","first-page":"228","DOI":"10.1196\/annals.1386.044","article-title":"Sex hormones and risk of liver tumor","volume":"1089","author":"Giannitrapani","year":"2006","journal-title":"Ann N Y Acad Sci"},{"key":"10.1111\/hpb.12387_bb0030","doi-asserted-by":"crossref","first-page":"926","DOI":"10.1016\/S0140-6736(73)92594-4","article-title":"Possible association between benign hepatomas and oral contraceptives","volume":"2","author":"Baum","year":"1973","journal-title":"Lancet"},{"key":"10.1111\/hpb.12387_bb0035","doi-asserted-by":"crossref","first-page":"2125","DOI":"10.3748\/wjg.v12.i13.2125","article-title":"Liver cell adenoma: a case report with clonal analysis and literature review","volume":"12","author":"Li","year":"2006","journal-title":"World J Gastroenterol"},{"key":"10.1111\/hpb.12387_bb0040","doi-asserted-by":"crossref","first-page":"462","DOI":"10.1002\/1097-0142(195405)7:3<462::AID-CNCR2820070308>3.0.CO;2-E","article-title":"Primary carcinoma of the liver a study of 100 cases among 48,900 necropsies","volume":"7","author":"Edmonson","year":"1954","journal-title":"Cancer"},{"key":"10.1111\/hpb.12387_bb0045","doi-asserted-by":"crossref","first-page":"524","DOI":"10.1136\/gut.32.5.524","article-title":"Focal nodular hyperplasia of the liver: results of treatment and options in management","volume":"32","author":"Pain","year":"1991","journal-title":"Gut"},{"key":"10.1111\/hpb.12387_bb0050","doi-asserted-by":"crossref","first-page":"591","DOI":"10.1016\/j.gassur.2003.11.012","article-title":"Multiple focal nodular hyperplasia of the liver in a 21\u2010year\u2010old woman","volume":"8","author":"Kim","year":"2004","journal-title":"J Gastrointest Surg"},{"key":"10.1111\/hpb.12387_bb0055","doi-asserted-by":"crossref","first-page":"1243","DOI":"10.2217\/fon.10.85","article-title":"An update on indications for treatment of solid hepatic neoplasms in noncirrhotic liver","volume":"6","author":"Pulvirenti","year":"2010","journal-title":"Future Oncol"},{"key":"10.1111\/hpb.12387_bb0060","doi-asserted-by":"crossref","first-page":"1679","DOI":"10.1016\/S0140-6736(05)61451-1","article-title":"Oral contraceptive intake with focal nodular hyperplasia of the liver","volume":"352","author":"Mathieu","year":"1998","journal-title":"Lancet"},{"key":"10.1111\/hpb.12387_bb0065","doi-asserted-by":"crossref","first-page":"735","DOI":"10.1016\/0016-5085(87)90026-6","article-title":"Hepatic estrogen receptor in human liver disease","volume":"92","author":"Porter","year":"1987","journal-title":"Gastroenterology"},{"key":"10.1111\/hpb.12387_bb0070","first-page":"1736","article-title":"Enlarged focal nodular hyperplasia of the liver under the influence of oral contraceptives","volume":"48","author":"Kubota","year":"2001","journal-title":"Hepatogastroenterology"},{"key":"10.1111\/hpb.12387_bb0075","first-page":"1355","article-title":"Expression of hormone receptors in benign hepatic tumors. An immunocytochemical study","volume":"116","author":"Masood","year":"1992","journal-title":"Arch Pathol Lab Med"},{"issue":"Suppl. 7","key":"10.1111\/hpb.12387_bb0080","first-page":"342","article-title":"The pathogenesis of focal nodular hyperplasia of the liver","volume":"19","author":"Wanless","year":"2004","journal-title":"J Gastroenterol Hepatol"},{"key":"10.1111\/hpb.12387_bb0085","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1148\/radiol.2291021284","article-title":"Prevalence of hepatic haemoangioma in patients with focal nodular hyperplasia: MRI analysis","volume":"229","author":"Vilgrain","year":"2003","journal-title":"Radiology"},{"key":"10.1111\/hpb.12387_bb0090","doi-asserted-by":"crossref","first-page":"1089","DOI":"10.1016\/j.ultrasmedbio.2004.08.004","article-title":"High prevalence of hepatic focal nodular hyperplasia in subjects with hereditary haemorrhagic telangiectasia","volume":"30","author":"Buscarini","year":"2004","journal-title":"Ultrasound Med Biol"},{"key":"10.1111\/hpb.12387_bb0095","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1136\/jcp.39.2.183","article-title":"Benign hepatic tumours and tumour\u2010like conditions in men","volume":"39","author":"Karhunen","year":"1986","journal-title":"J Clin Pathol"},{"key":"10.1111\/hpb.12387_bb0100","doi-asserted-by":"crossref","first-page":"787","DOI":"10.1002\/hep.1840110512","article-title":"Micronodular transformation (nodular regenerative hyperplasia) of the liver: a report of 64 cases among 2500 autopsies and a new classification of benign hepatocellular nodules","volume":"11","author":"Wanless","year":"1990","journal-title":"Hepatology"},{"key":"10.1111\/hpb.12387_bb0105","doi-asserted-by":"crossref","first-page":"2341","DOI":"10.1111\/j.1572-0241.2006.00783.x","article-title":"Clinicopathological features of focal nodular hyperplasia\u2010like nodules in 130 cirrhotic explant livers","volume":"101","author":"Libbrecht","year":"2006","journal-title":"Am J Gastroenterol"},{"key":"10.1111\/hpb.12387_bb0110","first-page":"113","article-title":"Focal nodular hyperplasia of the liver","volume":"85a","author":"Moesner","year":"1977","journal-title":"Acta Pathol Microbiol Scand"},{"key":"10.1111\/hpb.12387_bb0115","doi-asserted-by":"crossref","first-page":"1481","DOI":"10.1002\/1097-0142(197910)44:4<1481::AID-CNCR2820440443>3.0.CO;2-1","article-title":"The histology of liver tumours in oral contraceptive users during a national survey by the American College of Surgeons","volume":"44","author":"Nime","year":"1979","journal-title":"Cancer"},{"key":"10.1111\/hpb.12387_bb0120","doi-asserted-by":"crossref","first-page":"1674","DOI":"10.1002\/hep.1840220610","article-title":"Management of focal nodular hyperplasia and hepatocellular adenoma in young women: a series of 41 patients with clinical, radiological and pathological correlations","volume":"22","author":"Cherqui","year":"1995","journal-title":"Hepatology"},{"key":"10.1111\/hpb.12387_bb0125","doi-asserted-by":"crossref","first-page":"877","DOI":"10.1136\/gut.50.6.877","article-title":"Focal nodular hyperplasia of the liver in men: is presentation the same in men and women?","volume":"50","author":"Luciani","year":"2002","journal-title":"Gut"},{"key":"10.1111\/hpb.12387_bb0130","doi-asserted-by":"crossref","first-page":"2275","DOI":"10.1007\/s11605-011-1680-x","article-title":"Focal nodular hyperplasia \u2013 a review of myths and truths","volume":"15","author":"Nahm","year":"2011","journal-title":"J Gastrointest Surg"},{"key":"10.1111\/hpb.12387_bb0135","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1067\/mob.2002.120277","article-title":"Oral contraceptives and the risk of focal nodular hyperplasia of the liver: a case\u2013control study","volume":"186","author":"Scalori","year":"2002","journal-title":"Am J Obstet Gynecol"},{"key":"10.1111\/hpb.12387_bb0140","doi-asserted-by":"crossref","first-page":"194","DOI":"10.3109\/13625189809167253","article-title":"Modern oral contraceptive use and benign liver tumors: the German Benign Liver Tumor Case\u2010Control Study","volume":"3","author":"Heinemann","year":"1998","journal-title":"Eur J Contracept Reprod Health Care"},{"key":"10.1111\/hpb.12387_bb0145","first-page":"1008","article-title":"Natural history of focal nodular hyperplasia. A retrospective study of 44 cases","volume":"25","author":"D'Halluin","year":"2001","journal-title":"Gastroenterol Clin Biol"},{"key":"10.1111\/hpb.12387_bb0150","doi-asserted-by":"crossref","first-page":"560","DOI":"10.1016\/S0016-5085(00)70262-9","article-title":"Oral contraceptive use and focal nodular hyperplasia of the liver","volume":"118","author":"Mathieu","year":"2000","journal-title":"Gastroenterology"},{"key":"10.1111\/hpb.12387_bb0155","doi-asserted-by":"crossref","first-page":"88","DOI":"10.3109\/00365521.2012.737361","article-title":"No evidence of substantial growth progression or complications of large focal nodular hyperplasia during pregnancy","volume":"48","author":"Rifai","year":"2013","journal-title":"Scand J Gastroenterol"},{"key":"10.1111\/hpb.12387_bb0160","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1016\/j.amjsurg.2003.11.016","article-title":"A review of liver masses in pregnancy and a proposed algorithm for their diagnosis and management","volume":"187","author":"Cobey","year":"2004","journal-title":"Am J Surg"},{"key":"10.1111\/hpb.12387_bb0165","doi-asserted-by":"crossref","first-page":"1251","DOI":"10.1016\/S0140-6736(05)79318-1","article-title":"Pregnancy in women with observed focal nodular hyperplasia of the liver","volume":"351","author":"Weimann","year":"1998","journal-title":"Lancet"},{"key":"10.1111\/hpb.12387_bb0170","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1016\/S1665-2681(19)32124-6","article-title":"Symptomatic focal nodular hyperplasia during pregnancy: a case report","volume":"3","author":"Byrnes","year":"2004","journal-title":"Ann Hepatol"},{"key":"10.1111\/hpb.12387_bb0175","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1177\/000313480106700217","article-title":"Benign and solid tumours of the liver: relationship to sex, age, size of tumours and outcome","volume":"67","author":"Reddy","year":"2001","journal-title":"Am Surg"},{"key":"10.1111\/hpb.12387_bb0180","first-page":"210","article-title":"Rupture and haemorrhage of hepatic focal nodular hyperplasia","volume":"61","author":"Becker","year":"1995","journal-title":"Am Surg"},{"key":"10.1111\/hpb.12387_bb0185","first-page":"90","article-title":"Focal nodular hyperplasia presenting as acute abdomen","volume":"46","author":"Chang","year":"2005","journal-title":"Singapore Med J"},{"key":"10.1111\/hpb.12387_bb0190","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1016\/j.anchir.2005.07.007","article-title":"Rupture of hepatic focal nodular hyperplasia. About two cases","volume":"131","author":"Koch","year":"2006","journal-title":"Ann Chir"},{"key":"10.1111\/hpb.12387_bb0195","doi-asserted-by":"crossref","first-page":"310","DOI":"10.1016\/S0168-8278(01)00096-4","article-title":"A life threatening complication of focal nodular hyperplasia","volume":"35","author":"Hardwigsen","year":"2001","journal-title":"J Hepatol"},{"key":"10.1111\/hpb.12387_bb0200","doi-asserted-by":"crossref","first-page":"138","DOI":"10.1007\/s00534-004-0936-1","article-title":"Spontaneous rupture and haemorrhage of hepatic focal nodular hyperplasia in lobus caudatus","volume":"12","author":"Rahili","year":"2005","journal-title":"J Hepatobiliary Pancreat Surg"},{"key":"10.1111\/hpb.12387_bb0205","doi-asserted-by":"crossref","first-page":"808","DOI":"10.1046\/j.0007-1323.2001.01771.x","article-title":"Management of 155 patients with benign liver tumours","volume":"88","author":"Charny","year":"2001","journal-title":"Br J Surg"},{"key":"10.1111\/hpb.12387_bb0210","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1007\/s13304-013-0222-3","article-title":"Focal nodular hyperplasia and hepatic adenoma: current diagnosis and management","volume":"66","author":"Christiano","year":"2014","journal-title":"Updates Surg"},{"key":"10.1111\/hpb.12387_bb0215","doi-asserted-by":"crossref","first-page":"689","DOI":"10.1016\/j.amjsurg.2012.02.006","article-title":"Management of the focal nodular hyperplasia of the liver: evaluation of the surgical treatment comparing with observation only","volume":"204","author":"Perrakis","year":"2012","journal-title":"Am J Surg"}],"container-title":["HPB"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1365182X1531217X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1365182X1531217X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,24]],"date-time":"2025-10-24T00:00:16Z","timestamp":1761264016000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1365182X1531217X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,6]]},"references-count":42,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2015,6]]}},"alternative-id":["S1365182X1531217X"],"URL":"https:\/\/doi.org\/10.1111\/hpb.12387","relation":{},"ISSN":["1365-182X"],"issn-type":[{"value":"1365-182X","type":"print"}],"subject":[],"published":{"date-parts":[[2015,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Oestrogen hormone receptors in focal nodular hyperplasia","name":"articletitle","label":"Article Title"},{"value":"HPB","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1111\/hpb.12387","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2015 International Hepato-Pancreato-Biliary Association. Published by Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}