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In the regions of the hard palate and gingiva, the epithelium is keratinized like the epidermis. In the buccal region, the floor of the mouth and the underside of the tongue, the epithelium is non\u2010keratinized. The epithelium on the dorsum of the tongue is a specialized epithelium, but can be approximated as a mosaic of keratinized and non\u2010keratinized epithelia. The non\u2010keratinized epithelial regions do not produce a stratum corneum. Nuclei with intact <jats:styled-content style=\"fixed-case\">DNA<\/jats:styled-content> are retained in the superficial cells. In all regions, the outer portions of the epithelium provide a protective permeability barrier, which varies regionally. Antimicrobial lipids at the surfaces of the oral mucosa are an integral part of innate immunity.<\/jats:p>","DOI":"10.1111\/ics.12038","type":"journal-article","created":{"date-parts":[[2013,1,16]],"date-time":"2013-01-16T10:55:01Z","timestamp":1358333701000},"page":"220-223","source":"Crossref","is-referenced-by-count":57,"title":["Organization, barrier function and antimicrobial lipids of the oral mucosa"],"prefix":"10.1111","volume":"35","author":[{"given":"D. V.","family":"Dawson","sequence":"first","affiliation":[{"name":"Dows Institute for Dental Research University of Iowa N450 DSB Iowa City Iowa, 52242"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D. R.","family":"Drake","sequence":"additional","affiliation":[{"name":"Dows Institute for Dental Research University of Iowa N450 DSB Iowa City Iowa, 52242"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J. 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