{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,20]],"date-time":"2025-07-20T03:22:53Z","timestamp":1752981773963},"reference-count":45,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2017,4,6]],"date-time":"2017-04-06T00:00:00Z","timestamp":1491436800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100002551","name":"Seoul National University","doi-asserted-by":"publisher","award":["800\u201020160095"],"award-info":[{"award-number":["800\u201020160095"]}],"id":[{"id":"10.13039\/501100002551","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Intern J of Cosmetic Sci"],"published-print":{"date-parts":[[2017,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>Erythema is the most common presenting sign in patients with skin diseases, and various methods to treat erythema symptoms have become common. To evaluate changes in erythema, a reliable device that can support objective diagnosis is required. We developed a novel photography\u2010based system for erythema diagnosis that provides a high\u2010resolution three\u2010view photograph taken in a consistent photography environment with a curved surface light source and can be integrated with optimized image processing algorithms.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A new diagnostic algorithm was applied to photographs from 32 patients to determine areas of erythema automatically. To assess the performance in comparison to dermatologists\u2019 evaluations, five dermatologists independently evaluate the areas of erythema, and we defined an area called the clinical consensus area of erythema (<jats:styled-content style=\"fixed-case\">CCAE<\/jats:styled-content>), which is based on the majority opinion of dermatologists during evaluation. The <jats:styled-content style=\"fixed-case\">CCAE<\/jats:styled-content> values obtained were compared with the erythema areas determined by the system's diagnostic algorithm.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Forty\u2010one photographs with areas of erythema were evaluated by the proposed system and by dermatologists. The results obtained with the proposed system had a mean accuracy of 93.18% with a standard deviation of 3.52% when compared with the <jats:styled-content style=\"fixed-case\">CCAE<\/jats:styled-content> results. The results also showed that the proposed system could detect erythema areas without any pigmentation. In contrast to assessments by individual dermatologists, use of the <jats:styled-content style=\"fixed-case\">CCAE<\/jats:styled-content> reduced the amount of error that occurred owing to bias or subjectivity.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>A new erythema evaluation system was developed and validated through <jats:styled-content style=\"fixed-case\">CCAE<\/jats:styled-content>, suggesting that the system can support dermatologists\u2019 objective diagnoses of erythema.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ics.12393","type":"journal-article","created":{"date-parts":[[2017,2,8]],"date-time":"2017-02-08T17:56:39Z","timestamp":1486576599000},"page":"426-434","source":"Crossref","is-referenced-by-count":6,"title":["Development and clinical validation of a novel photography\u2010based skin erythema evaluation system: a comparison with the calculated consensus of dermatologists"],"prefix":"10.1111","volume":"39","author":[{"given":"M.","family":"Cho","sequence":"first","affiliation":[{"name":"Interdisciplinary Program for Bioengineering Graduate School Seoul National University Seoul 110\u2010744 Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D.\u2010H.","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Dermatology Seoul National University Hospital Seoul 110\u2010744 Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E. 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