{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,30]],"date-time":"2026-03-30T11:25:16Z","timestamp":1774869916125,"version":"3.50.1"},"reference-count":29,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2018,3,14]],"date-time":"2018-03-14T00:00:00Z","timestamp":1520985600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Intern J of Cosmetic Sci"],"published-print":{"date-parts":[[2018,4]]},"abstract":"Abstract<\/jats:title>Background<\/jats:title>Skin ageing results from intrinsic but also extrinsic factors of which UV<\/jats:styled-content> irradiation is a main cause. It is hence of interest to have means to protect skin from UV<\/jats:styled-content> irradiation\u2010induced damage. We selected an extract of the freshwater microalga Scenedesmus rubescens<\/jats:italic> and assessed its potential to protect skin from photoageing caused by UV<\/jats:styled-content> irradiation.<\/jats:p><\/jats:sec>Methods<\/jats:title>Skin cells in vitro<\/jats:italic> and ex vivo<\/jats:italic> were analysed for markers of UV<\/jats:styled-content> irradiation\u2010induced photodamage such as decreased viability, decreased collagen content, hyperpigmentation and sunburn cells.<\/jats:p><\/jats:sec>Results<\/jats:title>We found that a dry extract of the microalga Scenedesmus rubescens<\/jats:italic> was able to suppress cellular signs of ageing induced by UV<\/jats:styled-content> irradiation. It enhanced dermal fibroblast viability, rescued dermal collagen content, inhibited the formation of sunburn cells and inhibited tyrosinase activity.<\/jats:p><\/jats:sec>Conclusion<\/jats:title>An extract of Scenedesmus rubescens<\/jats:italic> showed broad activity against markers of UV<\/jats:styled-content> irradiation\u2010induced cutaneous ageing. It may therefore be used as a preventive or regenerative agent for anti\u2010ageing strategies.<\/jats:p><\/jats:sec>","DOI":"10.1111\/ics.12450","type":"journal-article","created":{"date-parts":[[2018,2,13]],"date-time":"2018-02-13T19:43:03Z","timestamp":1518550983000},"page":"187-192","source":"Crossref","is-referenced-by-count":19,"title":["Protective effects of an extract of the freshwater microalga Scenedesmus rubescens<\/i> on UV<\/scp>\u2010irradiated skin cells"],"prefix":"10.1111","volume":"40","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2216-7851","authenticated-orcid":false,"given":"R.","family":"Campiche","sequence":"first","affiliation":[{"name":"DSM Nutritional Products, Personal Care & Aroma Wurmisweg 576 CH\u20104303 Kaiseraugst Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P.","family":"Sandau","sequence":"additional","affiliation":[{"name":"IGV Institut f\u00fcr Getreideverarbeitung GmbH Arthur Scheunert Allee 40\u201041 D\u201014558 Nuthetal Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E.","family":"Kurth","sequence":"additional","affiliation":[{"name":"IGV Institut f\u00fcr Getreideverarbeitung GmbH Arthur Scheunert Allee 40\u201041 D\u201014558 Nuthetal Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Massironi","sequence":"additional","affiliation":[{"name":"Cutech srl Via San Marco 9\/M I\u201035129 Padua Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D.","family":"Imfeld","sequence":"additional","affiliation":[{"name":"DSM Nutritional Products, Personal Care & Aroma Wurmisweg 576 CH\u20104303 Kaiseraugst Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R.","family":"Schuetz","sequence":"additional","affiliation":[{"name":"DSM Nutritional Products, Personal Care & Aroma Wurmisweg 576 CH\u20104303 Kaiseraugst Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2018,3,14]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jdermsci.2016.09.015"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1101\/cshperspect.a015370"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/ics.12036"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms140612222"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.2147\/CCID.S44686"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00441-012-1501-x"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-2494.2007.00415.x"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1038\/skinbio.2013.176"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00371923"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0625.1993.tb00015.x"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms16047753"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2133.1990.tb16121.x"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.mad.2006.11.016"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.arr.2015.01.001"},{"key":"e_1_2_7_16_1","first-page":"127","article-title":"The sunburn cell","volume":"4","author":"Young A.R.","year":"1987","journal-title":"Photo\u2010dermatology"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-4632.2010.04474.x"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.fitote.2013.01.020"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biortech.2012.10.062"},{"key":"e_1_2_7_20_1","doi-asserted-by":"publisher","DOI":"10.1128\/AEM.00610-12"},{"key":"e_1_2_7_21_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0749.2006.00338.x"},{"key":"e_1_2_7_22_1","doi-asserted-by":"publisher","DOI":"10.5114\/ada.2017.67070"},{"key":"e_1_2_7_23_1","first-page":"2524","article-title":"The content and ratio of type I and III collagen in skin differ with age and injury","volume":"10","author":"Wang C.","year":"2011","journal-title":"African J. 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