{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T00:51:54Z","timestamp":1787014314647,"version":"build-2736575974"},"reference-count":30,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2022,6,17]],"date-time":"2022-06-17T00:00:00Z","timestamp":1655424000000},"content-version":"vor","delay-in-days":16,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100010558","name":"Beiersdorf","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100010558","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Intern J of Cosmetic Sci"],"published-print":{"date-parts":[[2022,6]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>The synergistic effects of VL and long wavelength UVA1 (VL\u2009+\u2009UVA1, 370\u2013700\u2009nm) on inducing pigmentation and erythema in skin have been demonstrated and linked to exacerbation of dermatologic conditions including melasma and post\u2010inflammatory hyperpigmentation. This study aimed to compare the photoprotection of organic sunscreens enriched with antioxidant (AO) combinations against VL\u2009+\u2009UVA1 induced biologic effects. The efficacy was compared with that offered by a commercially available tinted sunscreen.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      Ten healthy adult subjects with Fitzpatrick skin phototypes IV\u2013VI were enrolled (nine completed). VL\u2009+\u2009UVA1 dose of 380\u2009J\/cm\n                      <jats:sup>2<\/jats:sup>\n                      was utilized. Assessment methods were polarized photography, investigator global scoring and diffuse reflectance spectroscopy (DRS). Measurements were obtained at baseline and immediately, 24\u00a0h and 7\u2009days after irradiation.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Sites treated with tinted sunscreen product had significantly less pigmentation compared with untreated but irradiated skin at all time points. However, DRS results demonstrated that the 5\u2010AO sunscreen performed comparably or better than all sunscreens tested with relatively lower dyschromia, delayed erythema and pigmentation.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>These results highlight the potential of AO\u2010enriched sunscreens to be photoprotective against VL\u2009+\u2009UVA1. The combination of efficacy and the cosmetic appearance of this product may provide wider acceptability which is crucial considering the limited available means of protection against this waveband.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/ics.12785","type":"journal-article","created":{"date-parts":[[2022,5,19]],"date-time":"2022-05-19T06:39:46Z","timestamp":1652942386000},"page":"394-402","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":25,"title":["Evaluation of efficacy of antioxidant\u2010enriched sunscreen products against long wavelength ultraviolet A1 and visible light"],"prefix":"10.1111","volume":"44","author":[{"given":"Eduardo","family":"Ruvolo","sequence":"first","affiliation":[{"name":"Beiersdorf Inc.  Florham Park New Jersey USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2401-0794","authenticated-orcid":false,"given":"Wyatt","family":"Boothby\u2010Shoemaker","sequence":"additional","affiliation":[{"name":"Photomedicine and Photobiology Unit, Department of Dermatology Henry Ford Hospital  Detroit Michigan USA"},{"name":"Michigan State University College of Human Medicine  East Lansing Michigan USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nishant","family":"Kumar","sequence":"additional","affiliation":[{"name":"College of Literature, Science and Arts University of Michigan  Ann Arbor Michigan USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3137-5601","authenticated-orcid":false,"given":"Iltefat H.","family":"Hamzavi","sequence":"additional","affiliation":[{"name":"Photomedicine and Photobiology Unit, Department of Dermatology Henry Ford Hospital  Detroit Michigan USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1576-1115","authenticated-orcid":false,"given":"Henry W.","family":"Lim","sequence":"additional","affiliation":[{"name":"Photomedicine and Photobiology Unit, Department of Dermatology Henry Ford Hospital  Detroit Michigan USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2316-6375","authenticated-orcid":false,"given":"Indermeet","family":"Kohli","sequence":"additional","affiliation":[{"name":"Photomedicine and Photobiology Unit, Department of Dermatology Henry Ford Hospital  Detroit Michigan USA"},{"name":"Department of Physics and Astronomy Wayne State University  Detroit Michigan USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2022,6,17]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1038\/jid.2010.95"},{"issue":"5","key":"e_1_2_7_3_1","first-page":"197","article-title":"Quantification of visible light\u2010induced melanogenesis in human skin","volume":"5","author":"Porges S","year":"1988","journal-title":"Photo\u2010dermatology"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/pcmr.12273"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1039\/c1pp05202k"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0130949"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/bjd.15940"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/phpp.12523"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1751-1097.1984.tb03905.x"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1038\/jid.2011.476"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/php.13143"},{"issue":"2","key":"e_1_2_7_12_1","first-page":"95","article-title":"Immediate pigment darkening: description, kinetic and biological function","volume":"9","author":"Routaboul C","year":"1999","journal-title":"Eur J Dermatol"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1039\/c2pp25152c"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1039\/c9pp00425d"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.1991.01680030071009"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/phpp.12377"},{"key":"e_1_2_7_17_1","unstructured":"Ezekwe N.Efficacy evaluation of topical sunscreens against long wavelength ultraviolet A1 and visible light induced biological effects: preliminary findings. 30th annual meeting of the Photodermatology society. 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