{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,6]],"date-time":"2026-02-06T19:32:23Z","timestamp":1770406343602,"version":"3.49.0"},"reference-count":32,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2025,7,25]],"date-time":"2025-07-25T00:00:00Z","timestamp":1753401600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2025,7,25]],"date-time":"2025-07-25T00:00:00Z","timestamp":1753401600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Intern J of Cosmetic Sci"],"published-print":{"date-parts":[[2026,2]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>Despite accumulating data supporting the effectiveness of colloidal oatmeal\u2010based moisturizers in improving mild\u2010to\u2010moderate atopic dermatitis (AD), evidence in paediatric populations is limited. This study evaluated the tolerability and effectiveness of a colloidal oatmeal\u2010containing baby wash formulation in babies prone to AD, based on clinical and parental assessments.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>In this 4\u2010week, single\u2010centre, nonrandomized study of babies (3\u201336\u2009months) prone to AD (per an AD\u2010prone skin recruiting questionnaire developed in\u2010house), parents\/legal guardians used the baby wash on their babies \u22653 times per week (no more than once daily), each bath lasting \u226420\u2009min. The overall skin condition (scored from 0\/excellent to 3\/poor) and cutaneous tolerance scoring of dryness, redness\/erythema, rash\/irritation and tactile roughness on the baby's face, arms, legs and torso (each scored from 0\/none to 3\/severe) were assessed clinically at baseline, Week 1 and Week 4. Cutaneous tolerance scoring of burning\/stinging and itching on those body sites was evaluated by the parent per the latter scale at all visits. At study end, the parental questionnaire evaluated the level of agreement\/disagreement with statements regarding the baby wash. Safety measures included adverse events and changes in health (per the parents or clinicians).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Of 29 infant\u2010parent pairs enrolled, 24 (82.8%) completed the study. All 24 babies were White\/Caucasian; 13 (54.2%) were male. The overall skin condition mean score showed no statistically significant change from baseline (0.54) at Weeks 1 (0.33) and 4 (0.29). Per the investigator\u2010rated cutaneous tolerance scores, &gt;87% of body sites exhibited no dryness, redness\/erythema, rash\/irritation or tactile roughness at Week 4. For each parameter, significant improvements from baseline were observed at Week 4 for the combined skin sites (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.05). Per the parent\u2010rated cutaneous tolerance scores, nearly all sites had no burning\/stinging or itching at Week 4. Itching for the combined sites demonstrated significant improvements from baseline at Week 4 (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u20090.05). The parental questionnaire revealed statistically significantly more favourable experiences with the baby wash than unfavourable experiences. Four babies experienced five mild, treatment\u2010unrelated adverse events.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>The study findings indicate that the colloidal oatmeal\u2010containing baby wash was well tolerated and effective when used in babies with AD\u2010prone skin.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/ics.70010","type":"journal-article","created":{"date-parts":[[2025,7,25]],"date-time":"2025-07-25T08:45:37Z","timestamp":1753433137000},"page":"30-39","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["A colloidal oat\u2010containing baby wash is gentle and effective for atopic\u2010prone skin"],"prefix":"10.1111","volume":"48","author":[{"ORCID":"https:\/\/orcid.org\/0009-0005-7028-8024","authenticated-orcid":false,"given":"M. Catherine","family":"Mack","sequence":"first","affiliation":[{"name":"Kenvue Brands LLC  Summit New Jersey USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gabriella","family":"John","sequence":"additional","affiliation":[{"name":"Kenvue Brands LLC  Summit New Jersey USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Diana","family":"Friscia","sequence":"additional","affiliation":[{"name":"Kenvue Brands LLC  Summit New Jersey USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christine","family":"Perna","sequence":"additional","affiliation":[{"name":"Kenvue Brands LLC  Summit New Jersey USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Denise","family":"Bion","sequence":"additional","affiliation":[{"name":"Kenvue Brands LLC  Summit New Jersey USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Melody","family":"Ailsworth","sequence":"additional","affiliation":[{"name":"Lynchburg Pediatrics  Lynchburg Virginia USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kappa","family":"Peddy","sequence":"additional","affiliation":[{"name":"Lynchburg Pediatrics  Lynchburg Virginia USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Neena K.","family":"Tierney","sequence":"additional","affiliation":[{"name":"Kenvue Brands LLC  Summit New Jersey USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2025,7,25]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.1038\/jid.2009.133"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.yapd.2023.03.006"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41572\u2010018\u20100001\u2010z"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.anai.2020.12.020"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/s0140\u20106736(06)69283\u20100"},{"key":"e_1_2_9_7_1","doi-asserted-by":"publisher","DOI":"10.1159\/000370220"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.3122\/jabfm.2019.02.180225"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365\u20104632.2011.05176.x"},{"key":"e_1_2_9_10_1","doi-asserted-by":"publisher","DOI":"10.1067\/mjd.2002.124617"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11882\u2010009\u20100037\u2010y"},{"key":"e_1_2_9_12_1","first-page":"53","article-title":"Designing 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3\u2009years","volume":"66","author":"Cochet P","year":"2012","journal-title":"J Am Acad Dermatol"},{"issue":"2","key":"e_1_2_9_20_1","first-page":"167","article-title":"Colloidal oatmeal: history, chemistry and clinical properties","volume":"6","author":"Kurtz ES","year":"2007","journal-title":"J Drugs Dermatol"},{"issue":"7","key":"e_1_2_9_21_1","first-page":"804","article-title":"Colloidal oatmeal formulations as adjunct treatments in atopic dermatitis","volume":"11","author":"Fowler JF","year":"2012","journal-title":"J Drugs Dermatol"},{"issue":"10","key":"e_1_2_9_22_1","first-page":"1180","article-title":"Colloidal oatmeal formulations and the treatment of atopic dermatitis","volume":"13","author":"Fowler JF","year":"2014","journal-title":"J Drugs 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