{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,7]],"date-time":"2026-08-07T16:56:38Z","timestamp":1786121798282,"version":"build-2736575974"},"reference-count":38,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2026,1,12]],"date-time":"2026-01-12T00:00:00Z","timestamp":1768176000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2026,1,12]],"date-time":"2026-01-12T00:00:00Z","timestamp":1768176000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Intern J of Cosmetic Sci"],"published-print":{"date-parts":[[2026,8]]},"abstract":"Abstract<\/jats:title>\n \n Objective<\/jats:title>\n Solar lentigines and post\u2010inflammatory hyperpigmentation (PIH) are common pigmentation disorders, and they are usually differentiated by a trained dermatologist. Accurate identification of the spot type is essential for providing patients with the most appropriate skin treatment. The aim of this study was to evaluate the capacity of hyperspectral imaging (HSI) in characterizing and discriminating solar lentigines from PIH, that is, to identify the colorimetric features and chromophore concentrations associated with each pigmentation disorder.<\/jats:p>\n <\/jats:sec>\n \n Methods<\/jats:title>\n \n Acquisition of HSI was performed using a liquid\u2010crystal tuneable filter spectral scanning spectrometer. The recruited panel consisted of female Japanese subjects (\n n<\/jats:italic>\n \u2009=\u200911) with one solar lentigo on both the left and right cheeks. Five of these subjects also had one PIH spot on both the left and right cheeks.\n <\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n \n Significant differences were found in the mean difference relative to the surrounding skin between PIH spots and solar lentigines for the following features (all\n p<\/jats:italic>\n \u2009<\u20090.05): \u0394\n Oxyhaemoglobin<\/jats:italic>\n (PIH spots (2.3\u2009\u00b1\u20091.1)\u2009\u00d7\u200910\n \u22122<\/jats:sup>\n \u2009g\u00b7cm\u00b7L\n \u22121<\/jats:sup>\n vs. solar lentigines (\u22120.1\u2009\u00b1\u20090.6)\u2009\u00d7\u200910\n \u22122<\/jats:sup>\n \u2009g\u00b7cm\u00b7L\n \u22121<\/jats:sup>\n ), \u0394\n Deoxyhaemoglobin<\/jats:italic>\n (PIH spots (6.3\u2009\u00b1\u20092.6)\u2009\u00d7\u200910\n \u22122<\/jats:sup>\n \u2009g\u00b7cm\u00b7L\n \u22121<\/jats:sup>\n vs. solar lentigines (0.9\u2009\u00b1\u20091.7)\u2009\u00d7\u200910\n \u22122<\/jats:sup>\n \u2009g\u00b7cm\u00b7L\n \u22121<\/jats:sup>\n ), \u0394\n a<\/jats:italic>\n * values (PIH spots 5.3\u2009\u00b1\u20092.0 vs. solar lentigines 1.6\u2009\u00b1\u20091.3) and \u0394\n b<\/jats:italic>\n * values (PIH spots \u22121.2\u2009\u00b1\u20090.7 vs. solar lentigines \u22120.1\u2009\u00b1\u20090.4). No significant difference was observed in \u0394\n L<\/jats:italic>\n * values and \u0394\n Melanin<\/jats:italic>\n content between the two hyperpigmentation types (all\n p<\/jats:italic>\n \u2009>\u20090.05).\n <\/jats:p>\n <\/jats:sec>\n \n Conclusion<\/jats:title>\n \n Compared with solar lentigines, PIH spots displayed higher haemoglobin content and \u0394\n a<\/jats:italic>\n * values and lower \u0394\n b<\/jats:italic>\n * values. To strengthen these preliminary findings, further clinical studies need to be conducted on a larger cohort, aiming at confirming the benefit of HSI in accurately differentiating these two skin pigmentation disorders to support clinical assessment.\n <\/jats:p>\n <\/jats:sec>","DOI":"10.1111\/ics.70067","type":"journal-article","created":{"date-parts":[[2026,1,12]],"date-time":"2026-01-12T11:07:43Z","timestamp":1768216063000},"page":"738-746","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":0,"title":["Differentiating solar lentigines from post\u2010inflammatory hyperpigmentation with hyperspectral imaging: A pilot study"],"prefix":"10.1111","volume":"48","author":[{"ORCID":"https:\/\/orcid.org\/0009-0001-6815-1118","authenticated-orcid":false,"given":"Victor","family":"Egana","sequence":"first","affiliation":[{"name":"L'Or\u00e9al Research & Innovation Kawasaki 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