{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,18]],"date-time":"2026-06-18T03:31:07Z","timestamp":1781753467774,"version":"3.54.5"},"reference-count":54,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2013,12,7]],"date-time":"2013-12-07T00:00:00Z","timestamp":1386374400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Int J Dental Hygiene"],"published-print":{"date-parts":[[2014,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>A controlled clinical trial was conducted to evaluate the effects of oral prophylaxis on halitosis\u2010associated, immunological and microbiological parameters.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Thirty subjects were included in this controlled clinical trial (patients with generalized chronic periodontitis and controls without clinical attachment loss; each <jats:italic>n<\/jats:italic>\u00a0=\u00a015). Before oral prophylaxis and 14\u00a0days after (including tongue cleaning) volatile sulphur compounds (<jats:styled-content style=\"fixed-case\">VSC<\/jats:styled-content>), organoleptic scores and a tongue coating index were evaluated. The levels of <jats:styled-content style=\"fixed-case\">IL<\/jats:styled-content>\u20101\u03b2, <jats:styled-content style=\"fixed-case\">IL<\/jats:styled-content>\u20108, <jats:styled-content style=\"fixed-case\">IL<\/jats:styled-content>\u201010 and <jats:styled-content style=\"fixed-case\">MMP<\/jats:styled-content>\u20108 were measured in <jats:styled-content style=\"fixed-case\">GCF<\/jats:styled-content>, and also major periodontal pathogens were detected. Data were statistically analysed using <jats:sc>anova<\/jats:sc> and paired <jats:italic>t<\/jats:italic>\u2010test.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Supragingival plaque and calculus removal with combined tongue cleaning was able to reduce significantly (<jats:italic><jats:styled-content style=\"fixed-case\">P<\/jats:styled-content><\/jats:italic>\u00a0&lt;\u00a00.05) the <jats:styled-content style=\"fixed-case\">VSC<\/jats:styled-content> values in both groups (no significant differences between both groups). Two weeks after periodontal debridement, the <jats:styled-content style=\"fixed-case\">VSC<\/jats:styled-content> values were observed in the periodontitis group, but not in the control group, similar to the baseline values. The difference between the groups was statistically significant (<jats:italic><jats:styled-content style=\"fixed-case\">P<\/jats:styled-content><\/jats:italic>\u00a0&lt;\u00a00.05). Only a repeated prophylaxis session in the periodontitis group was able to reduce <jats:styled-content style=\"fixed-case\">VSC<\/jats:styled-content> values significantly in comparison with baseline (<jats:italic><jats:styled-content style=\"fixed-case\">P<\/jats:styled-content><\/jats:italic>\u00a0&lt;\u00a00.05). Organoleptic scores (10 and 30\u00a0cm) were significantly different (<jats:italic><jats:styled-content style=\"fixed-case\">P<\/jats:styled-content><\/jats:italic>\u00a0&lt;\u00a00.05) between both groups before and after the treatment. Periodontal pathogens and host\u2010derived markers were not significantly affected by a single prophylaxis session.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Oral prophylaxis may result in a significant decrease in <jats:styled-content style=\"fixed-case\">VSC<\/jats:styled-content> values. However, in periodontal diseases, a more complex treatment seems to be necessary.<\/jats:p><\/jats:sec>","DOI":"10.1111\/idh.12063","type":"journal-article","created":{"date-parts":[[2013,12,7]],"date-time":"2013-12-07T07:16:54Z","timestamp":1386400614000},"page":"199-207","source":"Crossref","is-referenced-by-count":17,"title":["Oral prophylaxis and its effects on halitosis\u2010associated and inflammatory parameters in patients with chronic periodontitis"],"prefix":"10.1111","volume":"12","author":[{"given":"A","family":"Guentsch","sequence":"first","affiliation":[{"name":"Policlinic of Prosthetic Dentistry and Material Science Jena University Hospital \u2013 Friedrich Schiller University Jena Germany"},{"name":"Marquette University School of Dentistry Milwaukee WI USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"W","family":"Pfister","sequence":"additional","affiliation":[{"name":"Institute of Medical Microbiology Jena University Hospital \u2013 Friedrich 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