{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,14]],"date-time":"2026-07-14T18:39:28Z","timestamp":1784054368293,"version":"3.55.0"},"reference-count":19,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2014,7,5]],"date-time":"2014-07-05T00:00:00Z","timestamp":1404518400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Int J Dental Hygiene"],"published-print":{"date-parts":[[2015,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objectives<\/jats:title><jats:p>The objective of this study was to compare the effectiveness of fluoride, essential oil (<jats:styled-content style=\"fixed-case\">EO<\/jats:styled-content>) and chlorhexidine (<jats:styled-content style=\"fixed-case\">CHX<\/jats:styled-content>)\u2010containing mouth rinses on dental plaque and gingivitis and to compare their relative efficacy in patients with and without dental caries.<\/jats:p><\/jats:sec><jats:sec><jats:title>Material and methods<\/jats:title><jats:p>A randomized, controlled, double\u2010 blind, crossover clinical trial was conducted for a period of 8\u00a0weeks. Thiry\u2010six qualifying subjects, aged 12\u201344\u00a0years, were included in the study. Subjects were divided into caries and caries\u2010free groups and were randomly assigned to one of the following mouth rinse groups: fluoride; <jats:styled-content style=\"fixed-case\">EO<\/jats:styled-content>;<jats:styled-content style=\"fixed-case\"> CHX<\/jats:styled-content> and saline as negative control. Subjects used their respective mouth rinse for a period of 7\u2010days each with 1\u2010week wash\u2010out periods. Primary efficacy variables were Quigley\u2013Hein plaque index (<jats:styled-content style=\"fixed-case\">PI<\/jats:styled-content>) and Loe and Silness gingival index.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Fluoride and <jats:styled-content style=\"fixed-case\">CHX<\/jats:styled-content> mouth rinses showed significant reduction in plaque after use of mouth rinses (<jats:italic>P<\/jats:italic>\u00a0&lt;\u00a00.05). However, no significant differences were observed with respect to each other in reducing gingivitis (<jats:italic>P<\/jats:italic>\u00a0&gt;\u00a00.05). Further significant differences were found in reducing plaque and gingivitis in caries\u2010free subjects in comparison to those with caries (<jats:italic>P<\/jats:italic>\u00a0&lt;\u00a00.05).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>All the three mouth rinses significantly reduced plaque accumulation and gingivitis especially in caries\u2010free subjects in comparison to those with caries, and amongst the three, fluoride and <jats:styled-content style=\"fixed-case\">CHX<\/jats:styled-content> proved to be more effective than <jats:styled-content style=\"fixed-case\">EO<\/jats:styled-content> mouth rinse.<\/jats:p><\/jats:sec>","DOI":"10.1111\/idh.12094","type":"journal-article","created":{"date-parts":[[2014,7,5]],"date-time":"2014-07-05T07:57:49Z","timestamp":1404547069000},"page":"104-109","source":"Crossref","is-referenced-by-count":25,"title":["Comparative effect of fluoride, essential oil and chlorhexidine mouth rinses on dental plaque and 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