{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,15]],"date-time":"2026-03-15T02:12:04Z","timestamp":1773540724671,"version":"3.50.1"},"reference-count":35,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2015,2,26]],"date-time":"2015-02-26T00:00:00Z","timestamp":1424908800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Int J Dental Hygiene"],"published-print":{"date-parts":[[2016,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>The aims of this study were to compare the volatile sulphur compounds (<jats:styled-content style=\"fixed-case\">VSC<\/jats:styled-content>)\u2010reducing effect of two commercial mouthrinses using a morning bad breath model and to assess the role of mechanical plaque control (<jats:styled-content style=\"fixed-case\">MPC<\/jats:styled-content>) when performed previously to mouthrinse use.<\/jats:p><\/jats:sec><jats:sec><jats:title>Patients and methods<\/jats:title><jats:p>Eleven volunteers with good oral health were enrolled in a double\u2010blind, randomized, six\u2010step crossover design study with a 7\u2010day washout period. Two commercial mouthrinses were tested using a saline solution (NaCl 0.9%) as a negative control: one mouthrinse contained 0.05% chlorhexidine, 0.05% cetylpyridinium chloride and 0.14% zinc lactate (<jats:styled-content style=\"fixed-case\">CHX<\/jats:styled-content>\u2010<jats:styled-content style=\"fixed-case\">CPC<\/jats:styled-content>\u2010Zn), while the other contained 0.05% chlorhexidine, 0.15% triclosan and 0.18% zinc pidolate (<jats:styled-content style=\"fixed-case\">CHX<\/jats:styled-content>\u2010triclosan\u2010Zn). A portable sulphide monitor (Halimeter<jats:sup>\u00ae<\/jats:sup>) was used for <jats:styled-content style=\"fixed-case\">VSC<\/jats:styled-content> quantification. Measurements were made at baseline, and 1, 3 and 5\u00a0h after rinsing. Significant differences were detected by analysis of variance.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>No significant differences between groups were detected at baseline. We were unable to demonstrate a significant influence of mechanical plaque control on the reduction of <jats:styled-content style=\"fixed-case\">VSC<\/jats:styled-content> levels when performed before mouthrinse use (<jats:italic>P<\/jats:italic>\u00a0=\u00a00.631). Both mouthrinses effectively lowered <jats:styled-content style=\"fixed-case\">VSC<\/jats:styled-content> levels in all test intervals (<jats:italic>P<\/jats:italic>\u00a0&lt;\u00a00.05). No statistically significant differences were found between mouthrinses in any of the test intervals (<jats:italic>P<\/jats:italic>\u00a0=\u00a00.629, 0.069 and 0.598 at 1, 3 and 5\u00a0h).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>This study demonstrated that <jats:styled-content style=\"fixed-case\">CHX<\/jats:styled-content>\u2010<jats:styled-content style=\"fixed-case\">CPC<\/jats:styled-content>\u2010Zn and <jats:styled-content style=\"fixed-case\">CHX<\/jats:styled-content>\u2010triclosan\u2010Zn have significant and similar effects in reducing <jats:styled-content style=\"fixed-case\">VSC<\/jats:styled-content> levels, which persist for at least 5\u00a0h. Such effects were independent of previous <jats:styled-content style=\"fixed-case\">MPC<\/jats:styled-content>, which failed to improve on the results of mouthrinse use alone.<\/jats:p><\/jats:sec>","DOI":"10.1111\/idh.12132","type":"journal-article","created":{"date-parts":[[2015,2,26]],"date-time":"2015-02-26T16:36:55Z","timestamp":1424968615000},"page":"202-208","source":"Crossref","is-referenced-by-count":12,"title":["Comparative effect of a new mouthrinse containing chlorhexidine, triclosan and zinc on volatile sulphur compounds: a randomized, crossover, double\u2010blind study"],"prefix":"10.1111","volume":"14","author":[{"given":"L","family":"Mendes","sequence":"first","affiliation":[{"name":"Department of Periodontology Faculty of Dental Medicine of Oporto Oporto University Porto Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J","family":"Coimbra","sequence":"additional","affiliation":[{"name":"Department of Periodontology Faculty of Dental Medicine 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