{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,12]],"date-time":"2026-10-12T18:53:55Z","timestamp":1791831235897,"version":"4.3.4"},"reference-count":39,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2015,4,7]],"date-time":"2015-04-07T00:00:00Z","timestamp":1428364800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"Schuelke & Mayr, Norderstedt, Germany"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Int J Dental Hygiene"],"published-print":{"date-parts":[[2016,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>To evaluate the effects of a periodontal therapy with subsequent application of an octenidine (<jats:styled-content style=\"fixed-case\">OCT<\/jats:styled-content>)\u2010based antiseptic in <jats:styled-content style=\"fixed-case\">HIV<\/jats:styled-content>\u2010positive patients receiving highly active antiretroviral therapy.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p><jats:styled-content style=\"fixed-case\">HIV<\/jats:styled-content>\u2010positive patients with a clinically diagnosed periodontal disease were randomly divided into two groups (<jats:italic>n<\/jats:italic>\u00a0=\u00a030\/group). Both groups initially received a periodontal therapy. Patients in the <jats:styled-content style=\"fixed-case\">OCT<\/jats:styled-content> group additionally used an <jats:styled-content style=\"fixed-case\">OCT<\/jats:styled-content>\u2010based mouthwash. Subgingival plaque samples and periodontal indices were analysed prior to treatment onset as well as one and 3\u00a0months post\u2010treatment.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Periodontal therapy has resulted in a significant decrease in the values of all periodontal indices one and 3\u00a0months following the therapy completion (<jats:italic>P<\/jats:italic>\u00a0=\u00a00.000). The effects of the two applied therapeutic protocols differed significantly in terms of the variation in the <jats:styled-content style=\"fixed-case\">PBI<\/jats:styled-content> (<jats:italic>F<\/jats:italic>\u00a0=\u00a04.617; <jats:italic>P<\/jats:italic>\u00a0=\u00a00.017) and the <jats:styled-content style=\"fixed-case\">PD<\/jats:styled-content> (<jats:italic>F<\/jats:italic>\u00a0=\u00a03.203; <jats:italic>P<\/jats:italic>\u00a0=\u00a00.044) value. In the patients in the <jats:styled-content style=\"fixed-case\">OCT<\/jats:styled-content> group, a more pronounced decrease in the <jats:styled-content style=\"fixed-case\">PBI<\/jats:styled-content> and <jats:styled-content style=\"fixed-case\">PD<\/jats:styled-content> was noted at 1\u2010month follow\u2010up as well as a greater increase in the <jats:styled-content style=\"fixed-case\">PD<\/jats:styled-content> value 3\u00a0months upon treatment completion. In the <jats:styled-content style=\"fixed-case\">OCT<\/jats:styled-content> group, no more atypical microorganisms were detectable 1\u00a0month post\u2010treatment, while in the control group they were found in 34.5% of patients.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The periodontal therapy bears good results in <jats:styled-content style=\"fixed-case\">HIV<\/jats:styled-content>\u2010positive patients. Additional administration of <jats:styled-content style=\"fixed-case\">OCT<\/jats:styled-content> contributes to the significant decline in the <jats:styled-content style=\"fixed-case\">PBI<\/jats:styled-content> and <jats:styled-content style=\"fixed-case\">DS<\/jats:styled-content> values and eliminates atypical microorganisms within 1\u00a0month post\u2010treatment. However, more favourable results were not noted in the <jats:styled-content style=\"fixed-case\">OCT<\/jats:styled-content> group at the 3\u2010month assessment.<\/jats:p><\/jats:sec>","DOI":"10.1111\/idh.12141","type":"journal-article","created":{"date-parts":[[2015,4,7]],"date-time":"2015-04-07T08:56:38Z","timestamp":1428396998000},"page":"108-116","source":"Crossref","is-referenced-by-count":7,"title":["Treatment of Periodontal Disease with an Octenidine\u2010based Antiseptic in HIV\u2010positive Patients"],"prefix":"10.1111","volume":"14","author":[{"given":"I","family":"Gu\u0161i\u0107","sequence":"first","affiliation":[{"name":"Department of Periodontology and Oral Medicine Clinic for Dentistry Faculty of Medicine University of Novi Sad Novi Sad Serbia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D","family":"Medi\u0107","sequence":"additional","affiliation":[{"name":"Institute of Public Health of Vojvodina Centre for Microbiology Novi Sad Serbia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M","family":"Radovanovi\u0107 Kanjuh","sequence":"additional","affiliation":[{"name":"Miofarm Export\u2010Import Ltd. 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