{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,15]],"date-time":"2026-09-15T19:03:01Z","timestamp":1789498981396,"version":"build-2803163510"},"reference-count":43,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2018,8,12]],"date-time":"2018-08-12T00:00:00Z","timestamp":1534032000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100007109","name":"Universit\u00e0 degli Studi di Ferrara","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100007109","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Int J Dental Hygiene"],"published-print":{"date-parts":[[2018,11]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Objectives<\/jats:title><jats:p>To evaluate the postsurgery gingival healing as well as plaque, gingival inflammation and staining levels following the use of a 0.2% chlorhexidine (CHX) solution with or without antidiscoloration system (ADS) and 0.2% hyaluronic acid (HA).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Patients undergoing flap surgery at sites with an intact or reduced but healthy periodontium participated in a parallel\u2010arm RCT. After surgery, patients used the assigned mouthrinse (CHX\u00a0+\u00a0HA\u00a0+\u00a0ADS or CHX) for 21\u00a0days. At days 7 and 21, the healing process was evaluated at experimental teeth using a composite index, namely the Gingival Healing Index (GHI). GHI score was obtained as the sum of the scores related to the severity of wound dehiscence (score 1\u20103) and the profile of the buccal and oral aspects of the papilla (score 1\u20103). Therefore, GHI ranged from 2 (worst quality of healing) to 6 (optimal quality of healing). Plaque Index (PlI), Gingival Index (GI), angulated bleeding score (AngBS), and tooth and tongue staining were also assessed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>In both groups, GHI assumed values of 5 or 6 at both days 7 and 21 in \u226550% of patients, and low median values of PlI, GI, AngBS and staining were observed during the 21\u2010day period. Except for a significantly lower GI in CHX group at day 7, no other significant intergroup differences were found.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Postsurgery plaque control based on either CHX or CHX\u00a0+\u00a0HA\u00a0+\u00a0ADS mouthrinses results in optimal plaque control and quality of early gingival healing along with limited tooth and tongue staining.<\/jats:p><\/jats:sec>","DOI":"10.1111\/idh.12361","type":"journal-article","created":{"date-parts":[[2018,8,13]],"date-time":"2018-08-13T03:03:17Z","timestamp":1534129397000},"page":"541-552","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":15,"title":["Clinical efficacy of a chlorhexidine\u2010based mouthrinse containing hyaluronic acid and an antidiscoloration system in patients undergoing flap surgery: A triple\u2010blind, parallel\u2010arm, randomized controlled 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