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The presence and number of eight selected putative periodontal pathogens [<jats:italic>Aggregatibacter actinomycetemcomitans<\/jats:italic> (<jats:italic>Aa<\/jats:italic>), <jats:italic>Porphyromonas gingivalis<\/jats:italic> (<jats:italic>Pg<\/jats:italic>), <jats:italic>Prevotella intermedia<\/jats:italic> (<jats:italic>Pi<\/jats:italic>), <jats:italic>Tannerella forsythia<\/jats:italic> (<jats:italic>Tf<\/jats:italic>), <jats:italic>Parvimonas micra<\/jats:italic> (<jats:italic>Pm<\/jats:italic>), <jats:italic>Fusobacterium nucleatum<\/jats:italic> (<jats:italic>Fn<\/jats:italic>), <jats:italic>Treponema denticola<\/jats:italic> (<jats:italic>Td<\/jats:italic>) and <jats:italic>Filifactor alocis<\/jats:italic> (<jats:italic>Fa<\/jats:italic>)] at intake and the percentage of teeth and sites with PPD &gt;5\u2009mm at intake and after treatment were extracted. Correlations within collected data were analysed with adjustment for multiple comparisons. Sub\u2010analyses were performed based on gender, age, and smoking and diabetic status.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Six hundred and sixty\u2010one patients could be included. The percentage of teeth with PPD &gt;5\u2009mm and the percentage of sites with PPD &gt;5\u2009mm at intake were significantly correlated to <jats:italic>Pi<\/jats:italic>, <jats:italic>Tf<\/jats:italic>, <jats:italic>Pm<\/jats:italic>, <jats:italic>Fn<\/jats:italic> and <jats:italic>Fa<\/jats:italic>. Patients with higher numbers of <jats:italic>these pathogens<\/jats:italic> at intake had a better treatment response. Those patients with higher numbers of <jats:italic>Aa<\/jats:italic> had a lower percentage of teeth and sites with PPD &gt;5\u2009mm at intake. Those with higher numbers of <jats:italic>Aa<\/jats:italic> also showed a smaller decrease in the percentage of sites with PPD &gt;5\u2009mm.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>The clinical periodontal status at intake and the response to treatment showed a weak but significant positive relationship for <jats:italic>Pi<\/jats:italic>, <jats:italic>Tf, Pm<\/jats:italic>, <jats:italic>Fn<\/jats:italic> and <jats:italic>Fa<\/jats:italic>. Conversely, higher numbers of <jats:italic>Aa<\/jats:italic> at intake were associated with more localized periodontitis and a reduced treatment response.<\/jats:p><\/jats:sec>","DOI":"10.1111\/idh.12665","type":"journal-article","created":{"date-parts":[[2023,1,12]],"date-time":"2023-01-12T10:24:11Z","timestamp":1673519051000},"page":"305-316","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Microbiological status at intake in relation to clinical periodontal status at intake and the response to non\u2010surgical periodontal therapy\u2014A retrospective analysis"],"prefix":"10.1111","volume":"21","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9496-8340","authenticated-orcid":false,"given":"Ilias","family":"Tahery","sequence":"first","affiliation":[{"name":"Department of Periodontology, Academic Center for Dentistry Amsterdam (ACTA) A joint venture between the Faculty of Dentistry of the University of Amsterdam and the Faculty of Dentistry of the Vrije Universiteit Amsterdam  Amsterdam The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8207-3320","authenticated-orcid":false,"given":"Fardin","family":"Ahmadzai","sequence":"additional","affiliation":[{"name":"Department of Periodontology, Academic Center for Dentistry Amsterdam (ACTA) A joint venture between the Faculty of Dentistry of the University of Amsterdam and the Faculty of Dentistry of the Vrije Universiteit Amsterdam  Amsterdam The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6656-6934","authenticated-orcid":false,"given":"Cees","family":"Valkenburg","sequence":"additional","affiliation":[{"name":"Department of Periodontology, Academic Center for Dentistry Amsterdam (ACTA) A joint venture between the Faculty of Dentistry of the University of Amsterdam and the Faculty of Dentistry of the Vrije Universiteit Amsterdam  Amsterdam The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7234-0037","authenticated-orcid":false,"given":"Dagmar E.","family":"Slot","sequence":"additional","affiliation":[{"name":"Department of Periodontology, Academic Center for Dentistry Amsterdam (ACTA) A joint venture between the Faculty of Dentistry of the University of Amsterdam and the Faculty of Dentistry of the Vrije Universiteit Amsterdam  Amsterdam The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5075-8384","authenticated-orcid":false,"given":"Fridus (G. 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