{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,17]],"date-time":"2025-12-17T13:06:14Z","timestamp":1765976774843,"version":"3.32.0"},"reference-count":46,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2024,5,19]],"date-time":"2024-05-19T00:00:00Z","timestamp":1716076800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Int J Dental Hygiene"],"published-print":{"date-parts":[[2025,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Purpose<\/jats:title><jats:p>To compare the effects of subgingival irrigation with 0.75% boric acid (BA) and 1% povidone\u2010iodine (PVP\u2010I) as an adjunct to scaling and root planing (SRP) on clinical and microbiologic parameters in the management of patients with periodontitis after a 12\u2010month follow\u2010up.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>Sixty systemically healthy individuals diagnosed with periodontitis were included in this double\u2010blind randomised clinical trial. The patients were randomly allocated to treatment groups: (1) SRP plus 0.75% BA and (2) SRP plus 1% PVP\u2010I. Whole\u2010mouth periodontals were clinically examined, and the counts of bacteria including <jats:italic>Aggregatibacter actinomycetemcomitans<\/jats:italic> (<jats:italic>Aa<\/jats:italic>), <jats:italic>Fusobacterium nucleatum<\/jats:italic> (<jats:italic>Fn<\/jats:italic>), <jats:italic>Porphyromonas gingivalis<\/jats:italic> (<jats:italic>Pg<\/jats:italic>), <jats:italic>Treponema denticola<\/jats:italic> (<jats:italic>Td<\/jats:italic>), <jats:italic>Tannerella forsythia<\/jats:italic> (<jats:italic>Tf<\/jats:italic>), <jats:italic>Solobacterium moorei<\/jats:italic> (<jats:italic>Sm<\/jats:italic>) and <jats:italic>Streptococcus salivarius<\/jats:italic> (<jats:italic>Ss<\/jats:italic>) were tested by real\u2010time polymerase chain reaction (PCR).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>All periodontal parameters and the counts of <jats:italic>Aa<\/jats:italic>, <jats:italic>Fn<\/jats:italic>, <jats:italic>Pg<\/jats:italic>, <jats:italic>Td<\/jats:italic>, <jats:italic>Tf<\/jats:italic>, <jats:italic>Sm<\/jats:italic> and <jats:italic>Ss<\/jats:italic> in both groups showed statistically significant reductions at T3, T6 and T12 compared to T0. Whole\u2010mouth or moderate or severe PD and CAL improvements were significantly found in the 0.75% BA group compared to the 1% PVP\u2010I group at T3, T6 and T12. The reduction in <jats:italic>Aa<\/jats:italic> or <jats:italic>Fn<\/jats:italic> and the reduction in <jats:italic>Ss<\/jats:italic> were significantly higher in the 0.75% BA group at T6 and T12 than in the 1% PVP\u2010I group.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>This study shows that subgingival irrigation with 0.75% BA may be an alternative to 1% PVP\u2010I because it promotes greater PD reductions and CAL gain, particularly up to 12\u2009months after treatment.<\/jats:p><\/jats:sec>","DOI":"10.1111\/idh.12819","type":"journal-article","created":{"date-parts":[[2024,5,20]],"date-time":"2024-05-20T04:25:16Z","timestamp":1716179116000},"page":"133-142","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Subgingival 0.75% boric acid vs 1% povidone\u2010iodine adjunctive to subgingival instrumentation in stage II and III periodontitis\u2013A double\u2010blind randomized clinical 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