{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,6]],"date-time":"2026-07-06T16:20:02Z","timestamp":1783354802474,"version":"3.54.6"},"reference-count":55,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2024,12,17]],"date-time":"2024-12-17T00:00:00Z","timestamp":1734393600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100005322","name":"Recep Tayyip Erdogan \u00dcniversitesi","doi-asserted-by":"publisher","award":["CIP\u20102020\u20101131"],"award-info":[{"award-number":["CIP\u20102020\u20101131"]}],"id":[{"id":"10.13039\/501100005322","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Int J Dental Hygiene"],"published-print":{"date-parts":[[2025,8]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:sec><jats:title>Objective<\/jats:title><jats:p>In this clinical study, chlorhexidine gluconate (CHX) was chosen as the positive control group, and the clinical and biochemical efficacy of mouthwashes with green tea, white tea and essential oil (EO) as the active ingredients were aimed to be examined comprehensively.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>A total of 112 participants with gingivitis were randomly assigned to four different groups and different mouthwashes were used for 4\u2009weeks: CHX\u2010MW group (as a positive control group), EO\u2010MW group, GT\u2010MW group and WT\u2010MW group. The effects of the mouthwashes on plaque, inflammation and dental staining were evaluated by indexed scores at the beginning and 4th week. Markers related to gingival inflammation and oxidative stress were evaluated on samples from the gingival crevicular fluid.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>In the 4th week, significant improvements in clinical parameters were found in all groups (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.05) with the more pronounced improvement in the CHX\u2010MW group (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.05). However, only the CHX caused a significant discolouration of both teeth and tongue (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.05). The levels of IL\u20101\u03b2 and MMP\u20108 were found to be lower in all groups compared to the first measurements (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.05). Furthermore, the antioxidant effect of EO mouthwash was found significantly low compared to the other three mouthwashes (<jats:italic>p<\/jats:italic>\u2009&lt;\u20090.05).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Green and white tea extracts provided clinical benefits in the short term (1\u2009month) with no statistical difference from each other and mouthwash with EO as the active ingredient while they provided a lower clinical benefit compared to CHX. Products with tea as the active ingredient may be an alternative to EO mouthwash for short\u2010term and long\u2010term use.<\/jats:p><\/jats:sec>","DOI":"10.1111\/idh.12890","type":"journal-article","created":{"date-parts":[[2024,12,17]],"date-time":"2024-12-17T03:52:05Z","timestamp":1734407525000},"page":"482-490","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Clinical and Biochemical Efficacies of Green and White Tea Extract Mouthwashes in the Management of Plaque\u2010Induced Gingivitis"],"prefix":"10.1111","volume":"23","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0318-2458","authenticated-orcid":false,"given":"Oguz","family":"Kose","sequence":"first","affiliation":[{"name":"Department of Periodontology, School of Dentistry Recep Tayyip Erdogan University  Rize Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yagmur","family":"Sarac Gul","sequence":"additional","affiliation":[{"name":"Department of Periodontology, School of Dentistry Recep Tayyip Erdogan University  Rize Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ahmet","family":"Altin","sequence":"additional","affiliation":[{"name":"Department of Periodontology, School of Dentistry Istanbul Kent University  Istanbul Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Semih Alperen","family":"Bostan","sequence":"additional","affiliation":[{"name":"Department of Periodontology, School of Dentistry Recep Tayyip Erdogan University  Rize Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ozlem","family":"Faiz","sequence":"additional","affiliation":[{"name":"Department of Chemistry, School of Arts and Science Recep Tayyip Erdogan University  Rize Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kerimali","family":"Akyildiz","sequence":"additional","affiliation":[{"name":"Department of Medical Services and Techniques, School of Health Care Services Vocational Recep Tayyip Erdogan University  Rize Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adnan","family":"Yilmaz","sequence":"additional","affiliation":[{"name":"Department of Biochemistry, School of Medicine Recep Tayyip Erdogan University  Rize Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,12,17]]},"reference":[{"key":"e_1_2_11_2_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.bdj.2012.1088"},{"key":"e_1_2_11_3_1","doi-asserted-by":"publisher","DOI":"10.1017\/erm.2013.8"},{"key":"e_1_2_11_4_1","doi-asserted-by":"publisher","DOI":"10.1080\/07853890600800103"},{"key":"e_1_2_11_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.2010.01563.x"},{"issue":"43","key":"e_1_2_11_6_1","first-page":"160","article-title":"The Role of Reactive Oxygen and Antioxidant Species in Periodontal Tissue Destruction","volume":"2007","author":"Chapple I. 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