{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T11:35:37Z","timestamp":1792064137467,"version":"4.4.0"},"reference-count":85,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2025,12,12]],"date-time":"2025-12-12T00:00:00Z","timestamp":1765497600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100004320","name":"Philips","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100004320","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Int J Dental Hygiene"],"published-print":{"date-parts":[[2026,2]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Aim<\/jats:title>\n                    <jats:p>This study aims to determine the efficacy and safety of AirFloss Ultra with essential oils (AFeo) compared to waxed dental floss (DF) as an adjunct to regular manual toothbrushing.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Material and Methods<\/jats:title>\n                    <jats:p>This study employed a randomly assigned, parallel, examiner\u2010blind design. Eighty\u2010two systemically healthy, right\u2010handed volunteers with \u2265\u200925% gingival bleeding in the lower jaw but without periodontitis were enrolled. After 3\u2009weeks of experimentally induced gingivitis, gingivitis reversal was assessed over the following 4\u2009weeks. Subjects were divided into two groups: one used AFeo in addition to twice\u2010daily manual toothbrushing with fluoride toothpaste, while the other used DF with the same brushing regimen. Bleeding On Marginal Probing (BOMP), Modified Silness and L\u00f6e Plaque Index (MPI), and approximal gingival abrasion scores (GAS) were recorded. These clinical parameters were analysed at baseline, intermediate time points, and study conclusion using appropriate parametric and non\u2010parametric statistical methods.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      The AFeo and DF groups showed a reduction in mean BOMP, MPI, and GAS scores. There were no significant differences in these parameters between the AFeo and DF groups at any time point (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&gt;\u20090.05). Furthermore, no serious adverse events were reported.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>No significant difference in efficacy was observed between the AirFloss Ultra filled with an essential oil solution and waxed dental floss when used alongside manual toothbrushing. This conclusion is based on assessments of gingival bleeding, dental plaque, and gingival abrasion scores in the lower jaw following experimentally induced gingivitis. Both products were also found to be safe for use.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/idh.70010","type":"journal-article","created":{"date-parts":[[2025,12,13]],"date-time":"2025-12-13T03:22:49Z","timestamp":1765596169000},"page":"3-15","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":2,"title":["Efficacy and Safety of\n                    <scp>AirFloss<\/scp>\n                    Ultra With Essential Oils Versus Waxed Dental Floss as Adjunct to Toothbrushing: A Randomised Controlled Clinical Trial"],"prefix":"10.1111","volume":"24","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2633-3236","authenticated-orcid":false,"given":"Tim M. J. A.","family":"Thomassen","sequence":"first","affiliation":[{"name":"Department of Periodontology Academic Centre for Dentistry Amsterdam (ACTA) University of Amsterdam and Vrije Universiteit Amsterdam  Amsterdam the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7234-0037","authenticated-orcid":false,"given":"Dagmar E.","family":"Slot","sequence":"additional","affiliation":[{"name":"Department of Periodontology Academic Centre for Dentistry Amsterdam (ACTA) University of Amsterdam and Vrije Universiteit Amsterdam  Amsterdam the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6713-6461","authenticated-orcid":false,"given":"Therese A.","family":"Elkerbout","sequence":"additional","affiliation":[{"name":"Department of Periodontology Academic Centre for Dentistry Amsterdam (ACTA) University of Amsterdam and Vrije Universiteit Amsterdam  Amsterdam the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1269-1710","authenticated-orcid":false,"given":"Eveline","family":"van der Sluijs","sequence":"additional","affiliation":[{"name":"Department of Periodontology Academic Centre for Dentistry Amsterdam (ACTA) University of Amsterdam and Vrije Universiteit Amsterdam  Amsterdam the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5075-8384","authenticated-orcid":false,"given":"Fridus A.","family":"Van der Weijden","sequence":"additional","affiliation":[{"name":"Department of Periodontology Academic Centre for Dentistry Amsterdam (ACTA) University of Amsterdam and Vrije Universiteit Amsterdam  Amsterdam the Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,12,12]]},"reference":[{"key":"e_1_2_12_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/JCPE.13290"},{"key":"e_1_2_12_3_1","doi-asserted-by":"publisher","DOI":"10.1002\/JPER.17\u20100721"},{"key":"e_1_2_12_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/JRE.12436"},{"key":"e_1_2_12_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/JRE.12805"},{"key":"e_1_2_12_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/J.1600\u2010051X.2009.01415.X"},{"key":"e_1_2_12_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/JCPE.12366"},{"key":"e_1_2_12_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/IDH.12563"},{"key":"e_1_2_12_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/IDH.12401"},{"key":"e_1_2_12_10_1","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD002281.PUB3"},{"key":"e_1_2_12_11_1","doi-asserted-by":"publisher","DOI":"10.1080\/00016357.2019.1697826"},{"key":"e_1_2_12_12_1","doi-asserted-by":"publisher","DOI":"10.3390\/DJ7020056"},{"key":"e_1_2_12_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/JCPE.12363"},{"issue":"3","key":"e_1_2_12_14_1","first-page":"79","article-title":"Interproximal Gingivitis and Plaque Reduction by Four Interdental Products","volume":"17","author":"Yost K. G.","year":"2006","journal-title":"Journal of Clinical Dentistry"},{"key":"e_1_2_12_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/J.1601\u20105037.2008.00336.X"},{"key":"e_1_2_12_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/J.1600\u2010051X.1978.TB01911.X"},{"key":"e_1_2_12_17_1","doi-asserted-by":"publisher","DOI":"10.1034\/J.1600\u2010051X.2000.027002134.X"},{"key":"e_1_2_12_18_1","doi-asserted-by":"publisher","DOI":"10.1111\/J.1600\u2010051X.1981.TB02029.X"},{"key":"e_1_2_12_19_1","doi-asserted-by":"publisher","DOI":"10.1177\/14653125231173708"},{"key":"e_1_2_12_20_1","doi-asserted-by":"publisher","DOI":"10.1111\/CLR.13638"},{"issue":"3","key":"e_1_2_12_21_1","first-page":"170","article-title":"Efficacy of the Use of a Water Flosser in Addition to an Electric Toothbrush on Clinical Signs of Inflammation: 4\u2010Week Randomized Controlled Trial","volume":"41","author":"Lyle D. M.","year":"2020","journal-title":"Compendium of Continuing Education in Dentistry"},{"key":"e_1_2_12_22_1","article-title":"Effect of Philips Sonicare AirFloss on Interproximal Plaque and Gingivitis","volume":"90","author":"Jager M.","year":"2011","journal-title":"Journal of Dental Research"},{"key":"e_1_2_12_23_1","unstructured":"S.Krell A.Kaler andJ.Wei \u201cIn\u2010Home Use Test to Evaluate Ease of Use for Philips Sonicare AirFloss Versus Reach String Floss and Waterpik Ultra Water Flosser. Philips Consumer Testing Data on File \u201d(2010)."},{"key":"e_1_2_12_24_1","first-page":"A36","article-title":"Gingival Health and Plaque Regrowth Response Following a Four\u2010Week Interdental Hygiene Intervention","volume":"28","author":"Mwatha A.","year":"2017","journal-title":"Journal of Clinical Dentistry"},{"key":"e_1_2_12_25_1","doi-asserted-by":"publisher","DOI":"10.1177\/08959374940080022401"},{"key":"e_1_2_12_26_1","doi-asserted-by":"publisher","DOI":"10.1902\/JOP.2007.060269"},{"key":"e_1_2_12_27_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2010.100266"},{"key":"e_1_2_12_28_1","doi-asserted-by":"publisher","DOI":"10.1111\/IDH.12069"},{"key":"e_1_2_12_29_1","doi-asserted-by":"publisher","DOI":"10.7326\/0003\u20104819\u2010152\u201011\u2010201006010\u201000232"},{"key":"e_1_2_12_30_1","doi-asserted-by":"publisher","DOI":"10.1136\/BMJ.G1687"},{"key":"e_1_2_12_31_1","doi-asserted-by":"publisher","DOI":"10.1111\/J.1600\u2010051X.2005.00851.X"},{"key":"e_1_2_12_32_1","doi-asserted-by":"publisher","DOI":"10.1111\/J.1600\u2010051X.1998.TB02509.X"},{"key":"e_1_2_12_33_1","doi-asserted-by":"publisher","DOI":"10.1111\/J.1600\u20100765.1994.TB01217.X"},{"key":"e_1_2_12_34_1","doi-asserted-by":"publisher","DOI":"10.1111\/J.1600\u2010051X.1994.TB00748.X"},{"key":"e_1_2_12_35_1","doi-asserted-by":"publisher","DOI":"10.1111\/J.1600\u2010051X.1993.TB00357.X"},{"key":"e_1_2_12_36_1","doi-asserted-by":"publisher","DOI":"10.1034\/J.1600\u2010051X.2003.00114.X"},{"key":"e_1_2_12_37_1","doi-asserted-by":"publisher","DOI":"10.3109\/00016356408993968"},{"key":"e_1_2_12_38_1","doi-asserted-by":"publisher","DOI":"10.1902\/JOP.1979.50.4.212"},{"key":"e_1_2_12_39_1","doi-asserted-by":"publisher","DOI":"10.1111\/J.1600\u2010051X.1998.TB02510.X"},{"key":"e_1_2_12_40_1","first-page":"S35","article-title":"A Comparison of Electric Toothbrushes in Their Potential to Cause Gingival Abrasion of Oral Soft Tissues","volume":"11","author":"Danser M. M.","year":"1998","journal-title":"American Journal of Dentistry"},{"key":"e_1_2_12_41_1","doi-asserted-by":"publisher","DOI":"10.1111\/J.1600\u2010051X.2004.00529.X"},{"key":"e_1_2_12_42_1","first-page":"S23","article-title":"A Comparison of the Efficacy of a Novel Electric Toothbrush and a Manual Toothbrush in the Treatment of Gingivitis","volume":"11","author":"Weijden F. A.","year":"1998","journal-title":"American Journal of Dentistry"},{"key":"e_1_2_12_43_1","doi-asserted-by":"publisher","DOI":"10.1002\/JPER.19\u20100443"},{"issue":"4","key":"e_1_2_12_44_1","first-page":"95","article-title":"A Split\u2010Mouth Comparison of a Three\u2010Dimensional\u2010Action Electric Toothbrush and a High\u2010Frequency Electric Toothbrush for Reducing Plaque and Gingivitis","volume":"3","author":"Putt M. S.","year":"2001","journal-title":"Journal of the International Academy of Periodontology"},{"key":"e_1_2_12_45_1","doi-asserted-by":"publisher","DOI":"10.1111\/J.1601\u20105037.2008.00284.X"},{"key":"e_1_2_12_46_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0300\u20105712(05)80005\u20103"},{"key":"e_1_2_12_47_1","doi-asserted-by":"publisher","DOI":"10.1111\/J.1600\u2010051X.2009.01495.X"},{"key":"e_1_2_12_48_1","doi-asserted-by":"publisher","DOI":"10.1034\/J.1600\u2010051X.2001.028010970.X"},{"key":"e_1_2_12_49_1","doi-asserted-by":"publisher","DOI":"10.1111\/J.1601\u20105037.2010.00487.X"},{"key":"e_1_2_12_50_1","doi-asserted-by":"publisher","DOI":"10.1902\/JOP.1965.36.3.177"},{"key":"e_1_2_12_51_1","doi-asserted-by":"publisher","DOI":"10.1111\/J.1600\u2010051X.1977.TB02270.X"},{"key":"e_1_2_12_52_1","doi-asserted-by":"publisher","DOI":"10.1177\/154407370201600106"},{"key":"e_1_2_12_53_1","doi-asserted-by":"publisher","DOI":"10.1073\/PNAS.2012578118\/\u2010\/DCSUPPLEMENTAL"},{"key":"e_1_2_12_54_1","doi-asserted-by":"publisher","DOI":"10.1111\/J.1600\u20100765.1993.TB02097.X"},{"key":"e_1_2_12_55_1","doi-asserted-by":"publisher","DOI":"10.14219\/jada.archive.1962.0184"},{"key":"e_1_2_12_56_1","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD008829.PUB2"},{"key":"e_1_2_12_57_1","doi-asserted-by":"publisher","DOI":"10.1177\/154405910608500404"},{"key":"e_1_2_12_58_1","doi-asserted-by":"publisher","DOI":"10.1034\/J.1600\u2010051X.2002.290302.X"},{"key":"e_1_2_12_59_1","doi-asserted-by":"publisher","DOI":"10.1080\/08927014.2012.662641"},{"key":"e_1_2_12_60_1","doi-asserted-by":"publisher","DOI":"10.1201\/9781351075640\u20104"},{"key":"e_1_2_12_61_1","doi-asserted-by":"publisher","DOI":"10.1902\/JOP.2003.74.7.1017"},{"key":"e_1_2_12_62_1","doi-asserted-by":"publisher","DOI":"10.1128\/AEM.71.7.3668\u20103673.2005"},{"key":"e_1_2_12_63_1","doi-asserted-by":"publisher","DOI":"10.1177\/0022034509344569"},{"key":"e_1_2_12_64_1","doi-asserted-by":"publisher","DOI":"10.1063\/1.2374950"},{"key":"e_1_2_12_65_1","doi-asserted-by":"publisher","DOI":"10.1111\/J.1600\u2010051X.2005.00836.X"},{"key":"e_1_2_12_66_1","doi-asserted-by":"publisher","DOI":"10.1111\/J.1600\u20100722.2005.00220.X"},{"key":"e_1_2_12_67_1","doi-asserted-by":"publisher","DOI":"10.1128\/AEM.67.6.2531\u20102537.2001"},{"issue":"9","key":"e_1_2_12_68_1","first-page":"80","article-title":"Use of a Water Flosser for Interdental Cleaning","volume":"32","author":"Lyle D. M.","year":"2011","journal-title":"Compendium of Continuing Education in Dentistry"},{"key":"e_1_2_12_69_1","doi-asserted-by":"publisher","DOI":"10.1002\/JPER.17\u20100368"},{"key":"e_1_2_12_70_1","doi-asserted-by":"publisher","DOI":"10.1902\/JOP.1990.61.11.663"},{"key":"e_1_2_12_71_1","doi-asserted-by":"publisher","DOI":"10.1111\/J.1601\u20105037.2008.00343.X"},{"key":"e_1_2_12_72_1","doi-asserted-by":"publisher","DOI":"10.1902\/jop.1990.61.2.112"},{"key":"e_1_2_12_73_1","doi-asserted-by":"publisher","DOI":"10.1111\/J.1600\u2010051X.1986.TB01435.X"},{"key":"e_1_2_12_74_1","doi-asserted-by":"publisher","DOI":"10.1902\/JOP.1989.60.6.310"},{"key":"e_1_2_12_75_1","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD012018.PUB2"},{"key":"e_1_2_12_76_1","doi-asserted-by":"publisher","DOI":"10.1128\/MBIO.02813\u201019"},{"key":"e_1_2_12_77_1","doi-asserted-by":"publisher","DOI":"10.1177\/0022034513510945"},{"issue":"2","key":"e_1_2_12_78_1","first-page":"107","article-title":"Diagnosis and Prevention Strategies for Dental Caries","volume":"3","author":"Lee Y.","year":"2013","journal-title":"Journal of Lifestyle Medicine"},{"key":"e_1_2_12_79_1","volume-title":"Draft Global Oral Health Action Plan (2023\u20132030)","author":"WHO","year":"2023"},{"key":"e_1_2_12_80_1","volume-title":"Oral Health","author":"World Health Organization"},{"key":"e_1_2_12_81_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMP1011024"},{"key":"e_1_2_12_82_1","doi-asserted-by":"publisher","DOI":"10.1111\/JCPE.12085"},{"key":"e_1_2_12_83_1","doi-asserted-by":"publisher","DOI":"10.1002\/CRE2.456"},{"key":"e_1_2_12_84_1","first-page":"41","article-title":"Plaquereduktion Mit der Sonicare AirFloss im Vergleich zur Zahnseide. Ergebnisse Einer Randomisiert Kontrollierten Cross\u2010Over\u2010Studie","volume":"26","author":"Hei\u00df\u2010Kisielewsky I.","year":"2015","journal-title":"Parodontologie"},{"key":"e_1_2_12_85_1","doi-asserted-by":"publisher","DOI":"10.1002\/CRE2.393"},{"key":"e_1_2_12_86_1","doi-asserted-by":"publisher","DOI":"10.1007\/S00784\u2010021\u201004167\u20101"}],"container-title":["International Journal of Dental Hygiene"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/idh.70010","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,12,30]],"date-time":"2025-12-30T04:18:28Z","timestamp":1767068308000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/idh.70010"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,12,12]]},"references-count":85,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2026,2]]}},"alternative-id":["10.1111\/idh.70010"],"URL":"https:\/\/doi.org\/10.1111\/idh.70010","archive":["Portico"],"relation":{},"ISSN":["1601-5029","1601-5037"],"issn-type":[{"value":"1601-5029","type":"print"},{"value":"1601-5037","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,12,12]]},"assertion":[{"value":"2024-11-01","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-11-10","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-12-12","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}