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We conducted a technological prospecting on intellectual property banks of Argentina, Brazil, Chile, Paraguay and Uruguay using the keywords \u2018caries\u2019, \u2018dental caries\u2019, \u2018dentistry\u2019, \u2018dental\u2019, \u2018oral\u2019 and \u2018buccal\u2019.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>From a total of 1740 patents, companies and industries had 63.56% applications, 50.4% were claimed for compositions and 37.01% for personal products. Brazil was the most expressive with 88.39% followed by Argentina with 8.16% patent deposits. The United States was the main country of origin of patents with 41.72%. Most of the patents are A61K code (61.09%) for medical, dental or hygienic purposes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>This study demonstrates the interest in patenting compositions and products for personal use, mainly by Brazilian and American industries\/companies. Based on the largest number of deposits founded, The United States demonstrates its strong influence on the international market. However, according to the patent application scenario observed, there is a need for innovation on new materials of prevention and treatment, also in detection and diagnosis techniques, as well as the protection of intellectual property developed and focused on the area of Cariology.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/idh.70022","type":"journal-article","created":{"date-parts":[[2026,4,7]],"date-time":"2026-04-07T10:48:39Z","timestamp":1775558919000},"page":"545-555","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Cariology\u2014Related Patents in South America: Innovations in Prevention, Management and Treatment"],"prefix":"10.1111","volume":"24","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9681-1761","authenticated-orcid":false,"given":"Mara Assef Leit\u00e3o","family":"Lotif","sequence":"first","affiliation":[{"name":"Universidade Federal do Cear\u00e1, Faculdade de Farm\u00e1cia, Odontologia e Enfermagem  Fortaleza Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3568-3089","authenticated-orcid":false,"given":"L\u00eddia Audrey Rocha","family":"Valadas","sequence":"additional","affiliation":[{"name":"Universidade Federal do Cear\u00e1, Faculdade de Farm\u00e1cia, Odontologia e Enfermagem  Fortaleza Brazil"},{"name":"Universidad de Buenos Aires, C\u00e1tedra de Odontolog\u00eda Preventiva y Comunitaria  Buenos Aires Argentina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4944-2080","authenticated-orcid":false,"given":"Rosueti Di\u00f3genes","family":"de Oliveira Filho","sequence":"additional","affiliation":[{"name":"Universidade Federal do Cear\u00e1, Faculdade de Farm\u00e1cia, Odontologia e Enfermagem  Fortaleza Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8538-9868","authenticated-orcid":false,"given":"Peter","family":"Bottenberg","sequence":"additional","affiliation":[{"name":"University of Ghent, School of Dentistry  Ghent Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7687-5805","authenticated-orcid":false,"given":"Aldo","family":"Squassi","sequence":"additional","affiliation":[{"name":"Universidad de Buenos Aires, C\u00e1tedra de Odontolog\u00eda Preventiva y Comunitaria  Buenos Aires Argentina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1539-2484","authenticated-orcid":false,"given":"Thereza Cristina Farias Botelho","family":"Dantas","sequence":"additional","affiliation":[{"name":"Paulo Pican\u00e7o College of Dentistry  Fortaleza Brazil"},{"name":"Christus University Center, College of Dentistry  Fortaleza Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4301-4739","authenticated-orcid":false,"given":"Mary Anne Medeiros","family":"Bandeira","sequence":"additional","affiliation":[{"name":"Universidade Federal do Cear\u00e1, Faculdade de Farm\u00e1cia, Odontologia e Enfermagem  Fortaleza Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2570-9265","authenticated-orcid":false,"given":"Marta Maria","family":"de Fran\u00e7a Fonteles","sequence":"additional","affiliation":[{"name":"Universidade Federal do Cear\u00e1, Faculdade de Farm\u00e1cia, Odontologia e Enfermagem  Fortaleza Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,4,7]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrdp.2017.30"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/jicd.12376"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.adaj.2017.11.006"},{"key":"e_1_2_10_5_1","first-page":"1","article-title":"Dental Hypomineralization Treatment: A Systematic Review","volume":"31","author":"Cunha Coelho A. 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