{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T16:01:01Z","timestamp":1790697661529,"version":"4.1.0"},"reference-count":38,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2026,4,14]],"date-time":"2026-04-14T00:00:00Z","timestamp":1776124800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,4,14]],"date-time":"2026-04-14T00:00:00Z","timestamp":1776124800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/doi.wiley.com\/10.1002\/tdm_license_1.1"}],"funder":[{"DOI":"10.13039\/501100002322","name":"Coordena\u00e7\u00e3o de Aperfei\u00e7oamento de Pessoal de N\u00edvel Superior","doi-asserted-by":"publisher","award":["Finance Code 001"],"award-info":[{"award-number":["Finance Code 001"]}],"id":[{"id":"10.13039\/501100002322","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003758","name":"Funda\u00e7\u00e3o de Amparo \u00e0 Pesquisa e ao Desenvolvimento Cient\u00edfico e Tecnol\u00f3gico do Maranh\u00e3o","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003758","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Int J Dental Hygiene"],"published-print":{"date-parts":[[2026,11]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:label\/>\n                    <jats:p>Dental materials with the potential for caries progression prevention have been an attractive alternative to minimally invasive treatments.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>This randomized controlled split\u2010mouth clinical trial aimed to assess, after 18\u2009months, the retention, restoration quality, and caries progression or arrestment of active moderate carious lesions (International Caries Detection and Assessment System [ICDAS] 3\u20134) sealed with resin\u2010modified glass ionomer cement (RMGIC) and 45S5 bioglass\u2010enriched RMGIC (RMGIC\/45S5).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methodology<\/jats:title>\n                    <jats:p>A total of 52\u2009molars with occlusal caries (ICDAS 3\u20134) were selected. For this split\u2010mouth clinical trial, the permanent molars without mechanical preparation were randomly sealed with RMGIC or RMGIC\/45S5. After 18\u2009months, the restorations were compared with the initial treatment (baseline) regarding retention, quality of the remaining material (anatomical shape, marginal adaptation, surface texture, and marginal discoloration), and clinical\/radiographic caries progression. The Wilcoxon and Fisher's exact tests were used for data evaluation.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      After 18\u2009months, no statistically significant differences were found in the retention and material quality of teeth treated with RMGIC or RMGIC\/45S5 (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&gt;\u20090.05). The clinical and radiographic evaluations showed no statistical difference between the materials when considering caries arrestment and progression (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&gt;\u20090.05).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>The addition of 45S5 bioglass to RMGIC did not change the retention, restoration quality, and caries progression or arrestment levels after 18\u2009months of follow\u2010up.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/idh.70058","type":"journal-article","created":{"date-parts":[[2026,4,15]],"date-time":"2026-04-15T03:20:38Z","timestamp":1776223238000},"page":"581-591","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":1,"title":["Clinical Performance of Bioglass\u2010Enriched Resin Modified Glass Ionomer in Sealing Moderate Carious Lesions: An 18\u2010Month Split\u2010Mouth Clinical Trial"],"prefix":"10.1111","volume":"24","author":[{"given":"Juliana Aguiar Costa","family":"Mesquita","sequence":"first","affiliation":[{"name":"Dental Post\u2010Graduation Program, Department of Dentistry I Federal University of Maranh\u00e3o (UFMA)  S\u00e3o Lu\u00eds MA Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ana Carolina Soares","family":"Diniz","sequence":"additional","affiliation":[{"name":"Dental Post\u2010Graduation Program, Department of Dentistry I Federal University of Maranh\u00e3o (UFMA)  S\u00e3o Lu\u00eds MA Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9621-8711","authenticated-orcid":false,"given":"Mayenne Rabelo","family":"Araujo","sequence":"additional","affiliation":[{"name":"Department of Dentistry I Federal University of Maranh\u00e3o  S\u00e3o Lu\u00eds MA Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Etevaldo Matos","family":"Maia Filho","sequence":"additional","affiliation":[{"name":"Dental Post\u2010Graduation Program CEUMA University  S\u00e3o Lu\u00eds MA Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8634-188X","authenticated-orcid":false,"given":"Leily Macedo","family":"Firoozmand","sequence":"additional","affiliation":[{"name":"Dental Post\u2010Graduation Program, Department of Dentistry I Federal University of Maranh\u00e3o (UFMA)  S\u00e3o Lu\u00eds MA Brazil"},{"name":"Department of Dentistry I Federal University of Maranh\u00e3o  S\u00e3o Lu\u00eds MA Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2026,4,14]]},"reference":[{"issue":"7","key":"e_1_2_12_2_1","first-page":"109","article-title":"Interventions for Treating Cavitated or Dentine Carious Lesions","volume":"19","author":"Schwendicke F.","year":"2021","journal-title":"Cochrane Database of Systematic Reviews"},{"key":"e_1_2_12_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmbbm.2022.105304"},{"key":"e_1_2_12_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/cdoe.12025"},{"key":"e_1_2_12_5_1","doi-asserted-by":"publisher","DOI":"10.1177\/154405910408301s07"},{"key":"e_1_2_12_6_1","doi-asserted-by":"publisher","DOI":"10.1177\/0022034516639276"},{"key":"e_1_2_12_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jdent.2015.02.009"},{"key":"e_1_2_12_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jdent.2019.07.001"},{"key":"e_1_2_12_9_1","first-page":"1","article-title":"A Review of Glass\u2010Ionomer Cements for Clinical Dentistry","volume":"28","author":"Sidhu S.","year":"2016","journal-title":"J Funct Biomater"},{"key":"e_1_2_12_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijadhadh.2021.102933"},{"key":"e_1_2_12_11_1","first-page":"515","article-title":"Sugar, fluoride, pH and microbial homeostasis in dental plaque","volume":"87","author":"Marsh P. 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