{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T19:36:19Z","timestamp":1790278579267,"version":"4.1.0"},"reference-count":28,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2020,8,1]],"date-time":"2020-08-01T00:00:00Z","timestamp":1596240000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,8,1]],"date-time":"2020-08-01T00:00:00Z","timestamp":1596240000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2020,12,1]],"date-time":"2020-12-01T00:00:00Z","timestamp":1606780800000},"content-version":"vor","delay-in-days":122,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/501100008530","name":"European Regional Development Fund","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100008530","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004895","name":"European Social Fund","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004895","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["International Dental Journal"],"published-print":{"date-parts":[[2020,8]]},"DOI":"10.1111\/idj.12550","type":"journal-article","created":{"date-parts":[[2020,2,11]],"date-time":"2020-02-11T07:26:51Z","timestamp":1581406011000},"page":"303-307","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":11,"title":["Relationship between deciduous molar hypomineralisation and parameters of bone metabolism in preschool children"],"prefix":"10.1016","volume":"70","author":[{"given":"Wieland","family":"Elger","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christina","family":"Illge","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wieland","family":"Kiess","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antje","family":"K\u00f6rner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J\u00fcrgen","family":"Kratzsch","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Annett","family":"Schrock","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christian","family":"Hirsch","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1111\/idj.12550_bib1","doi-asserted-by":"crossref","first-page":"551","DOI":"10.1177\/0022034512440450","article-title":"Deciduous molar hypomineralization and molar incisor hypomineralization","volume":"91","author":"Elfrink","year":"2012","journal-title":"J Dent Res"},{"key":"10.1111\/idj.12550_bib2","doi-asserted-by":"crossref","first-page":"e91057","DOI":"10.1371\/journal.pone.0091057","article-title":"Pre- and postnatal determinants of deciduous molar hypomineralisation in 6-year-old children. The generation R study","volume":"9","author":"Elfrink","year":"2014","journal-title":"PLoS ONE"},{"key":"10.1111\/idj.12550_bib3","doi-asserted-by":"crossref","first-page":"648","DOI":"10.1111\/ipd.12425","article-title":"The severity and degree of hypomineralisation in teeth and its influence on oral hygiene and caries prevalence in children","volume":"28","author":"Ebel","year":"2018","journal-title":"Int J Paediatr Dent"},{"key":"10.1111\/idj.12550_bib4","doi-asserted-by":"crossref","first-page":"278","DOI":"10.1046\/j.1365-263x.2000.00210.x","article-title":"Enamel hypomineralization of permanent first molars: a morphological study and survey of possible aetiological factors","volume":"10","author":"J\u00e4levik","year":"2000","journal-title":"Int J Paediatr Dent"},{"key":"10.1111\/idj.12550_bib5","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1111\/j.1365-263X.2009.01026.x","article-title":"Factors increasing the caries risk of second primary molars in 5-year-old Dutch children","volume":"20","author":"Elfrink","year":"2010","journal-title":"Int J Paediatr Dent"},{"key":"10.1111\/idj.12550_bib6","doi-asserted-by":"crossref","first-page":"974","DOI":"10.1016\/j.jdent.2013.08.024","article-title":"Mineral content in teeth with deciduous molar hypomineralisation (DMH)","volume":"41","author":"Elfrink","year":"2013","journal-title":"J Dent"},{"key":"10.1111\/idj.12550_bib7","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1007\/BF03262713","article-title":"Aetiology of Molar-Incisor Hypomineralisation: A systematic review","volume":"11","author":"Alaluusua","year":"2010","journal-title":"Eur Arch Paediatr Dent"},{"key":"10.1111\/idj.12550_bib8","doi-asserted-by":"crossref","first-page":"342","DOI":"10.1111\/cdoe.12229","article-title":"Etiology of molar incisor hypomineralization \u2013 a systematic review","volume":"44","author":"Silva","year":"2016","journal-title":"Community Dent Oral Epidemiol"},{"key":"10.1111\/idj.12550_bib9","first-page":"266","article-title":"Cheese molars: a pilot study of the etiology of hypocalcifications in first permanent molars","volume":"62","author":"van Amerongen","year":"1995","journal-title":"ASDC J Dent Child"},{"key":"10.1111\/idj.12550_bib10","doi-asserted-by":"crossref","first-page":"1945","DOI":"10.1359\/jbmr.2002.17.11.1945","article-title":"Function of mutant (G1144A) tissue-nonspecific ALP gene from hypophosphatasia","volume":"17","author":"Watanabe","year":"2002","journal-title":"J Bone Miner Res"},{"key":"10.1111\/idj.12550_bib11","doi-asserted-by":"crossref","first-page":"381","DOI":"10.1177\/0022034514561657","article-title":"Elevated serum 25(OH)-vitamin D levels are negatively correlated with molar-incisor hypomineralization","volume":"94","author":"K\u00fchnisch","year":"2015","journal-title":"J Dent Res"},{"key":"10.1111\/idj.12550_bib12","doi-asserted-by":"crossref","first-page":"963","DOI":"10.1056\/NEJMcibr1407247","article-title":"Vitamin B12 deficiency and bone health","volume":"371","author":"Clemens","year":"2014","journal-title":"N Engl J Med"},{"key":"10.1111\/idj.12550_bib13","doi-asserted-by":"crossref","first-page":"142","DOI":"10.5005\/jp-journals-10005-1424","article-title":"Assessment of vitamin B12 and Its correlation with dental caries and gingival diseases in 10- to 14-year-old children: a cross-sectional study","volume":"10","author":"Hugar","year":"2017","journal-title":"Int J Clin Pediatr Dent"},{"key":"10.1111\/idj.12550_bib14","doi-asserted-by":"crossref","first-page":"691","DOI":"10.1186\/s12889-015-1983-z","article-title":"The LIFE-adult-study: objectives and design of a population-based cohort study with 10,000 deeply phenotyped adults in Germany","volume":"15","author":"Loeffler","year":"2015","journal-title":"BMC Public Health"},{"key":"10.1111\/idj.12550_bib15","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1007\/s10654-016-0216-9","article-title":"The LIFE child study: a population-based perinatal and pediatric cohort in Germany","volume":"32","author":"Poulain","year":"2017","journal-title":"Eur J Epidemiol"},{"key":"10.1111\/idj.12550_bib16","doi-asserted-by":"crossref","first-page":"1021","DOI":"10.1186\/1471-2458-12-1021","article-title":"The LIFE child study: a life course approach to disease and health","volume":"12","author":"Quante","year":"2012","journal-title":"BMC Public Health"},{"key":"10.1111\/idj.12550_bib17","doi-asserted-by":"crossref","first-page":"449","DOI":"10.1007\/s00784-017-2132-0","article-title":"aMMP-8 in correlation to caries and periodontal condition in adolescents-results of the epidemiologic LIFE child study","volume":"22","author":"Schmidt","year":"2018","journal-title":"Clin Oral Investig"},{"key":"10.1111\/idj.12550_bib18","unstructured":"World Medical Association. WMA Declaration of Helsinki \u2013 Ethical Principles for Medical Research Involving Human Subjects 2018. Available from: https:\/\/www.wma.net\/policies-post\/wma-declaration-of-helsinki-ethical-principles-for-medical-research-involving-human-subjects\/. Accessed 9 October 2018"},{"key":"10.1111\/idj.12550_bib19","doi-asserted-by":"crossref","first-page":"807","DOI":"10.1007\/s001120170107","article-title":"Percentiles of body mass index in children and adolescents evaluated from different regional German studies","volume":"149","author":"Kromeyer-Hauschild","year":"2001","journal-title":"Monatsschr Kinderheilkd"},{"key":"10.1111\/idj.12550_bib20","doi-asserted-by":"crossref","first-page":"975","DOI":"10.1016\/j.dsx.2018.12.017","article-title":"Association of body mass index with serum calcium and phosphate levels","volume":"13","author":"Jafari-Giv","year":"2019","journal-title":"Diabetes Metab Syndr"},{"key":"10.1111\/idj.12550_bib21","doi-asserted-by":"crossref","first-page":"420","DOI":"10.1037\/0033-2909.86.2.420","article-title":"Intraclass correlations: uses in assessing rater reliability","volume":"86","author":"Shrout","year":"1979","journal-title":"Psychol Bull"},{"key":"10.1111\/idj.12550_bib22","first-page":"110","article-title":"Judgement criteria for molar incisor hypomineralisation (MIH) in epidemiologic studies: a summary of the European meeting on MIH held in Athens, 2003","volume":"4","author":"Weerheijm","year":"2003","journal-title":"Eur J Paediatr Dent"},{"key":"10.1111\/idj.12550_bib23","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1007\/BF03262716","article-title":"Best clinical practice guidance for clinicians dealing with children presenting with Molar-Incisor-Hypomineralisation (MIH): an EAPD policy document","volume":"11","author":"Lygidakis","year":"2010","journal-title":"Eur Arch Paediatr Dent"},{"key":"10.1111\/idj.12550_bib24","doi-asserted-by":"crossref","first-page":"452","DOI":"10.1097\/PAT.0000000000000274","article-title":"Trends and physiology of common serum biochemistries in children aged 0\u201318 years","volume":"47","author":"Loh","year":"2015","journal-title":"Pathology"},{"key":"10.1111\/idj.12550_bib25","doi-asserted-by":"crossref","first-page":"379","DOI":"10.1002\/ar.1092390405","article-title":"Morphological studies of hypomineralized enamel of rat pups on calcium-deficient diet, and of its changes after return to normal diet","volume":"239","author":"Bonucci","year":"1994","journal-title":"Anat Rec"},{"key":"10.1111\/idj.12550_bib26","doi-asserted-by":"crossref","first-page":"1043","DOI":"10.1177\/002215540004800803","article-title":"Morphological and immunocytochemical analyses on the effects of diet-induced hypocalcemia on enamel maturation in the rat incisor","volume":"48","author":"Nanci","year":"2000","journal-title":"J Histochem Cytochem"},{"key":"10.1111\/idj.12550_bib27","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1016\/S0003-9969(00)00113-8","article-title":"Secondary ion mass spectrometry and X-ray microanalysis of hypomineralized enamel in human permanent first molars","volume":"46","author":"J\u00e4levik","year":"2001","journal-title":"Arch Oral Biol"},{"key":"10.1111\/idj.12550_bib28","first-page":"83","article-title":"Hard teeth tissues in rats with experimental rickets. Examinations in electron scanning microscope and microanalyser","volume":"20","author":"Knychalska-Karwan","year":"1982","journal-title":"Folia Histochem Cytochem (Krakow)"}],"container-title":["International Dental Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fidj.12550","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/idj.12550","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1111\/idj.12550","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0020653920314350?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0020653920314350?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/idj.12550","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,9,17]],"date-time":"2025-09-17T10:44:57Z","timestamp":1758105897000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0020653920314350"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,8]]},"references-count":28,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2020,8]]}},"alternative-id":["S0020653920314350"],"URL":"https:\/\/doi.org\/10.1111\/idj.12550","relation":{},"ISSN":["0020-6539"],"issn-type":[{"value":"0020-6539","type":"print"}],"subject":[],"published":{"date-parts":[[2020,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Relationship between deciduous molar hypomineralisation and parameters of bone metabolism in preschool children","name":"articletitle","label":"Article Title"},{"value":"International Dental Journal","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1111\/idj.12550","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2020 FDI World Dental Federation. Published by Elsevier Inc.","name":"copyright","label":"Copyright"}]}}