{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,27]],"date-time":"2026-01-27T12:51:24Z","timestamp":1769518284734,"version":"3.49.0"},"reference-count":26,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2012,10,24]],"date-time":"2012-10-24T00:00:00Z","timestamp":1351036800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Int Endodontic J"],"published-print":{"date-parts":[[2013,4]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>To detect and quantify dentine sialoprotein (<jats:styled-content style=\"fixed-case\">DSP<\/jats:styled-content>) in the gingival crevicular fluid (<jats:styled-content style=\"fixed-case\">GCF<\/jats:styled-content>) of luxated teeth.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methodology<\/jats:title><jats:p>Eighteen subjects were enroled and distributed as follows. Group I (<jats:italic>n<\/jats:italic>\u00a0=\u00a06, positive control): subjects with primary second molar teeth undergoing physiological root resorption. Group <jats:styled-content style=\"fixed-case\">II<\/jats:styled-content> (<jats:italic>n<\/jats:italic>\u00a0=\u00a06, negative control): subjects with permanent mature maxillary central incisors. Subjects with a recent history (&lt;1\u00a0week) of luxation injury were included in group <jats:styled-content style=\"fixed-case\">III<\/jats:styled-content> (<jats:italic>n<\/jats:italic>\u00a0=\u00a06, test group) and standardized digital radiographs with a superimposed mesh gauge were exposed at various time intervals. Percentage of radiographic root resorption (%<jats:styled-content style=\"fixed-case\">RRR<\/jats:styled-content>) was calculated. <jats:styled-content style=\"fixed-case\">GCF<\/jats:styled-content> was collected using microcapillary pipettes. <jats:styled-content style=\"fixed-case\">DSP<\/jats:styled-content> in the <jats:styled-content style=\"fixed-case\">GCF<\/jats:styled-content> was quantified using enzyme\u2010linked immunosorbant assay. Group <jats:styled-content style=\"fixed-case\">III<\/jats:styled-content> was subjected to Spearman's rank test to establish the correlation between the concentration of <jats:styled-content style=\"fixed-case\">DSP<\/jats:styled-content> and %<jats:styled-content style=\"fixed-case\">RRR<\/jats:styled-content> at 6\u00a0weeks, 3 and 6\u00a0months.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Quantifiable amounts of <jats:styled-content style=\"fixed-case\">DSP<\/jats:styled-content> were released in the <jats:styled-content style=\"fixed-case\">GCF<\/jats:styled-content> of subjects in Group I and <jats:styled-content style=\"fixed-case\">III<\/jats:styled-content>. However, the protein was not detected in Group <jats:styled-content style=\"fixed-case\">II<\/jats:styled-content>. Detectable quantities of <jats:styled-content style=\"fixed-case\">DSP<\/jats:styled-content> were observed in the <jats:styled-content style=\"fixed-case\">GCF<\/jats:styled-content> of luxated teeth before any radiographic evidence of root resorption (base line radiograph). A positive correlation was established at 6\u00a0weeks (<jats:italic>r<\/jats:italic>\u00a0=\u00a00.795), 3 (<jats:italic>r<\/jats:italic>\u00a0=\u00a00.755) and 6\u00a0month (<jats:italic>r<\/jats:italic>\u00a0=\u00a00.837) between the release of <jats:styled-content style=\"fixed-case\">DSP<\/jats:styled-content> and %<jats:styled-content style=\"fixed-case\">RRR<\/jats:styled-content> (<jats:italic>P<\/jats:italic>\u00a0&lt;\u00a00.05).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Dentine sialoprotein was released in the <jats:styled-content style=\"fixed-case\">GCF<\/jats:styled-content> of luxated teeth and its concentration correlated with the active and remission phases of this pathological process. Further investigation is required to establish a potentially noninvasive aid for diagnosing and monitoring root resorption.<\/jats:p><\/jats:sec>","DOI":"10.1111\/iej.12001","type":"journal-article","created":{"date-parts":[[2012,9,12]],"date-time":"2012-09-12T00:30:03Z","timestamp":1347409803000},"page":"371-378","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Dentine sialoprotein expression in gingival crevicular fluid during trauma\u2010induced root resorption"],"prefix":"10.1111","volume":"46","author":[{"given":"V.","family":"Kumar","sequence":"first","affiliation":[{"name":"Department of Conservative Dentistry &amp; Endodontics Centre for Dental Education &amp; Research All India Institute of Medical Sciences New Delhi India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Logani","sequence":"additional","affiliation":[{"name":"Department of Conservative Dentistry &amp; Endodontics Centre for Dental Education &amp; Research All India Institute of Medical Sciences New Delhi India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"N.","family":"Shah","sequence":"additional","affiliation":[{"name":"Department of Conservative Dentistry &amp; Endodontics Centre for Dental Education &amp; Research All India Institute of Medical Sciences New Delhi India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2012,10,24]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1038\/bdj.2007.328"},{"key":"e_1_2_7_3_1","first-page":"101","article-title":"A time\u2010related study of periodontal healing and root resorption activity after replantation of mature permanent incisors in monkeys","volume":"4","author":"Andreasen JO","year":"1980","journal-title":"Swedish Dental Journal"},{"key":"e_1_2_7_4_1","first-page":"1358","volume-title":"Endodontics","author":"Andreasen JO","year":"2008"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-9657.1987.tb00167.x"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.matbio.2004.07.008"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.archoralbio.2006.08.018"},{"key":"e_1_2_7_8_1","volume-title":"Immunology provides important techniques with which to investigate proteins. Section 4.3. Biochemistry","author":"Berg JM","year":"2002"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0934-8832(11)80030-2"},{"key":"e_1_2_7_10_1","first-page":"169","article-title":"The nature and functional significance of dentin extracellular matrix proteins","volume":"39","author":"Butler WT","year":"1995","journal-title":"International Journal of Developmental Biology"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1080\/03008200390152287"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1359\/jbmr.1997.12.12.2040"},{"key":"e_1_2_7_13_1","first-page":"189","article-title":"Microscopical aspects of root resorption of human deciduous teeth","volume":"97","author":"Francini E","year":"1992","journal-title":"Italian Journal of Anatomy & Embryology"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0757.2003.03103.x"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.2334\/josnusd.49.1"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1834-7819.2007.tb00519.x"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1093\/ejo\/26.5.491"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.1093\/ejo\/cjn024"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1747-4477.2007.00056.x"},{"key":"e_1_2_7_20_1","doi-asserted-by":"publisher","DOI":"10.1590\/S1678-77572010000300019"},{"key":"e_1_2_7_21_1","first-page":"161","article-title":"Evidence in favour of an anti\u2010invasion factor in cementum or periodontal membrane of human teeth","volume":"88","author":"Lindskog S","year":"1980","journal-title":"Scandinavian Journal of Dental Research"},{"key":"e_1_2_7_22_1","doi-asserted-by":"publisher","DOI":"10.1093\/ejo\/26.1.25"},{"key":"e_1_2_7_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.joen.2009.05.029"},{"key":"e_1_2_7_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajodo.2009.03.046"},{"key":"e_1_2_7_25_1","doi-asserted-by":"publisher","DOI":"10.1002\/aja.1001830404"},{"key":"e_1_2_7_26_1","first-page":"e 239","article-title":"Efficacy of a bioactive alloplast, in the treatment of human periodontal osseous defects\u2010a clinical study","volume":"16","author":"Thomas B","year":"2011","journal-title":"Medicina Oral, Patolog\u00eda Oral y Cirug\u00eda Bucal"},{"key":"e_1_2_7_27_1","doi-asserted-by":"publisher","DOI":"10.1034\/j.1601-1546.2002.10106.x"}],"container-title":["International Endodontic Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fiej.12001","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/iej.12001","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,30]],"date-time":"2023-10-30T13:37:12Z","timestamp":1698673032000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/iej.12001"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,10,24]]},"references-count":26,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2013,4]]}},"alternative-id":["10.1111\/iej.12001"],"URL":"https:\/\/doi.org\/10.1111\/iej.12001","archive":["Portico"],"relation":{},"ISSN":["0143-2885","1365-2591"],"issn-type":[{"value":"0143-2885","type":"print"},{"value":"1365-2591","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,10,24]]},"assertion":[{"value":"2012-04-14","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2012-08-24","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2012-10-24","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}