{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,12]],"date-time":"2026-06-12T23:01:29Z","timestamp":1781305289300,"version":"3.54.1"},"reference-count":50,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2012,11,9]],"date-time":"2012-11-09T00:00:00Z","timestamp":1352419200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Int Endodontic J"],"published-print":{"date-parts":[[2013,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>To investigate the use of 3D plastic models, printed from cone beam computed tomography (<jats:styled-content style=\"fixed-case\">CBCT<\/jats:styled-content>) data, for accurate diagnosis and conservative treatment of a complex case of dens invaginatus.<\/jats:p><\/jats:sec><jats:sec><jats:title>Summary<\/jats:title><jats:p>A chronic apical abscess with a draining sinus tract was diagnosed during the treatment planning stage of orthodontic therapy. Radiographic examination revealed a large radiolucent area associated with an invaginated right maxillary central incisor, which was found to contain a vital pulp. The affected tooth was strategic in the dental arch. Conventional periapical radiographs provided only partial information about the invagination and its relationship with the main root canal and with the periapical tissues. A limited\u2010volume <jats:styled-content style=\"fixed-case\">CBCT<\/jats:styled-content> scan of the maxilla did not show evidence of communication between the infected invagination and the pulp in the main root canal, which could explain the pulp vitality. A novel method was adopted to allow for instrumentation, disinfection and filling of the invagination, without compromising the vitality of the pulp in the complex root canal system. The <jats:styled-content style=\"fixed-case\">CBCT<\/jats:styled-content> data were used to produce precise 3D plastic models of the tooth. These models facilitated the treatment planning process and the trial of treatment approaches. This approach allowed the vitality of the pulp to be maintained in the complex root canal space of the main root canal whilst enabling the healing of the periapical tissues.<\/jats:p><\/jats:sec><jats:sec><jats:title>Key learning points<\/jats:title><jats:p>\n<jats:list list-type=\"bullet\">\n\n<jats:list-item><jats:p>Even when extensive periapical pathosis is associated with a tooth with type III dens invaginatus, pulp sensibility tests should be performed.<\/jats:p><\/jats:list-item>\n\n<jats:list-item><jats:p>CBCT is a diagnostic tool that may allow for the management of such teeth with complex anatomy.<\/jats:p><\/jats:list-item>\n\n<jats:list-item><jats:p>3D printed plastic models may be a valuable aid in the process of assessing and planning effective treatment modalities and practicing them <jats:italic>ex vivo<\/jats:italic> before actually performing the clinical procedure.<\/jats:p><\/jats:list-item>\n\n<jats:list-item><jats:p>Unconventional technological approaches may be required for detailed treatment planning of complex cases of dens invaginatus.<\/jats:p><\/jats:list-item>\n<\/jats:list>\n<\/jats:p><\/jats:sec>","DOI":"10.1111\/iej.12013","type":"journal-article","created":{"date-parts":[[2012,9,21]],"date-time":"2012-09-21T17:55:36Z","timestamp":1348250136000},"page":"275-288","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":66,"title":["The diagnosis and conservative treatment of a complex type 3 dens invaginatus using cone beam computed tomography (CBCT) and 3D plastic models"],"prefix":"10.1111","volume":"46","author":[{"given":"A.","family":"Kfir","sequence":"first","affiliation":[{"name":"Department of Endodontology Tel Aviv University Tel Aviv Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Y.","family":"Telishevsky\u2010Strauss","sequence":"additional","affiliation":[{"name":"Department of Endodontology Tel Aviv University Tel Aviv Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Leitner","sequence":"additional","affiliation":[{"name":"Panorama Naharya Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Z.","family":"Metzger","sequence":"additional","affiliation":[{"name":"Department of Endodontology Tel Aviv University Tel Aviv Israel"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2012,11,9]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2591.2008.01468.x"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2842.2010.02065.x"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0531-5131(01)00119-4"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0096-6347(43)90330-8"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-263x.2001.00205.x"},{"key":"e_1_2_7_7_1","first-page":"209","article-title":"Dens in dente: report of three cases","volume":"45","author":"Boyne PJ","year":"1952","journal-title":"The Journal of the American Dental Association"},{"key":"e_1_2_7_8_1","first-page":"1211","article-title":"Endodontic applications of cone\u2010beam volumetric tomography","volume":"9","author":"Cotton TP","year":"2007","journal-title":"Journal of Endodontics"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0030-4220(78)80014-0"},{"key":"e_1_2_7_10_1","doi-asserted-by":"crossref","first-page":"4775","DOI":"10.1242\/dev.127.22.4775","article-title":"Sonic hedgehong regulates growth and morphogenesis of the tooth","volume":"127","author":"Dassule HR","year":"2000","journal-title":"Development"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1747-4477.2005.tb00320.x"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.joen.2010.08.009"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.joen.2011.02.001"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2591.2011.01866.x"},{"key":"e_1_2_7_15_1","first-page":"621","article-title":"Zur frage des dens in dente","volume":"3","author":"Fischer CH","year":"1936","journal-title":"Deutsche Zahn\u2010, Mundund Kieferheilkunde"},{"key":"e_1_2_7_16_1","first-page":"115","article-title":"Dens invaginatus. 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