{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,7]],"date-time":"2026-07-07T11:26:56Z","timestamp":1783423616199,"version":"3.54.6"},"reference-count":30,"publisher":"Wiley","issue":"7","license":[{"start":{"date-parts":[[2013,1,21]],"date-time":"2013-01-21T00:00:00Z","timestamp":1358726400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Int Endodontic J"],"published-print":{"date-parts":[[2013,7]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>To investigate the effect of supplemental lingual infiltration (<jats:styled-content style=\"fixed-case\">LI<\/jats:styled-content>) of mandibular molars following an inferior alveolar nerve block (<jats:styled-content style=\"fixed-case\">IANB<\/jats:styled-content>) plus buccal infiltration (<jats:styled-content style=\"fixed-case\">BI<\/jats:styled-content>) in patients with irreversible pulpitis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methodology<\/jats:title><jats:p>Eighty adult patients diagnosed with irreversible pulpitis participated in this prospective study. All patients received standard <jats:styled-content style=\"fixed-case\">IANB<\/jats:styled-content> via injection of 4\u00a0mL of 2% lidocaine with 1\u00a0:\u00a0100\u00a0000 epinephrine. Ten minutes after the <jats:styled-content style=\"fixed-case\">IANB<\/jats:styled-content>, patients with numbness of the lower lip were randomly divided into two groups. In the <jats:styled-content style=\"fixed-case\">BI<\/jats:styled-content> group, 40 patients received supplemental <jats:styled-content style=\"fixed-case\">BI<\/jats:styled-content> of 0.9\u00a0mL of 4% articaine with 1\u00a0:\u00a0100\u00a0000 epinephrine. In the buccal plus lingual infiltration (<jats:styled-content style=\"fixed-case\">BLI<\/jats:styled-content>) group, 40 patients received supplemental <jats:styled-content style=\"fixed-case\">BI<\/jats:styled-content> of 0.9\u00a0mL of 4% articaine with 1\u00a0:\u00a0100\u00a0000 epinephrine and, subsequently, <jats:styled-content style=\"fixed-case\">LI<\/jats:styled-content>s with the same anaesthetic solution and dose. Endodontic access cavity preparation began 15\u00a0min after the <jats:styled-content style=\"fixed-case\">IANB<\/jats:styled-content>. Pain during treatment was recorded using a <jats:styled-content style=\"fixed-case\">H<\/jats:styled-content>eft\u2013<jats:styled-content style=\"fixed-case\">P<\/jats:styled-content>arker visual analogue scale. Success was defined when pain was \u2018none\u2019 or \u2018mild\u2019 on endodontic access and initial instrumentation. The pain was estimated and statistically analysed by the chi\u2010squared test (\u03b1\u00a0=\u00a00.05).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The success rates for the <jats:styled-content style=\"fixed-case\">BI<\/jats:styled-content> and <jats:styled-content style=\"fixed-case\">BLI<\/jats:styled-content> groups were 70% and 62.5%, respectively. No statistical difference was found between the two groups (<jats:italic>P<\/jats:italic>\u00a0=\u00a00.478).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Supplemental LIs are not recommended for administration in mandibular molars with irreversible pulpitis, because they do not improve the anaesthetic success after <jats:styled-content style=\"fixed-case\">IANB<\/jats:styled-content> plus <jats:styled-content style=\"fixed-case\">BI<\/jats:styled-content>.<\/jats:p><\/jats:sec>","DOI":"10.1111\/iej.12042","type":"journal-article","created":{"date-parts":[[2012,11,28]],"date-time":"2012-11-28T23:25:17Z","timestamp":1354145117000},"page":"660-665","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":21,"title":["Anaesthetic efficacy of supplemental lingual infiltration of mandibular molars after inferior alveolar nerve block plus buccal infiltration in patients with irreversible 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