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The roots were smoothened and cut to obtain 36 specimens. During chemomechanical preparation of the root canals, 5.25% NaOC<\/jats:styled-content>l was used as the irrigant. The specimens were then divided into six groups according to the final irrigant used: control group \u2013 immersed in distilled water (DW<\/jats:styled-content>) for 1\u00a0min; chlorhexidine (CHX<\/jats:styled-content>) group \u2013 in 2% CHX for 1\u00a0min; NaOC<\/jats:styled-content>l group \u2013 in 5.25% NaOC<\/jats:styled-content>l for 1\u00a0min; EDTA<\/jats:styled-content> group \u2013 in 17% EDTA<\/jats:styled-content> for 5\u00a0min, EDTA<\/jats:styled-content>\/CHX<\/jats:styled-content> group \u2013 in EDTA<\/jats:styled-content>, followed by intermediate flushing with DW<\/jats:styled-content> and then immersed in CHX; EDTA<\/jats:styled-content>\/NaOC<\/jats:styled-content>l group \u2013 in EDTA<\/jats:styled-content>, followed by intermediate flushing with DW<\/jats:styled-content> and then immersed in NaOC<\/jats:styled-content>l. After the treatments, all groups were washed with DW<\/jats:styled-content> to remove all traces of the irrigants. Afterwards, the samples were dried and attached to a glass base. AFM<\/jats:styled-content> tips containing AH<\/jats:styled-content> Plus and Real Seal SE<\/jats:styled-content> sealers were used to obtain force\u2013distance curves with regard to dentine\u2010treated surfaces. Data were analysed statistically using nonparametric tests with the significance level set at P<\/jats:italic>\u00a0<\u00a00.05.<\/jats:p><\/jats:sec>Results<\/jats:title>In the groups with smear layer, a final flush with CHX<\/jats:styled-content> and NaOC<\/jats:styled-content>l resulted in significantly higher Fad values than the control group for both sealers (P<\/jats:italic>\u00a0<\u00a00.001). When smear layer was removed, the highest Fad values associated with AH<\/jats:styled-content> Plus occurred with a final flush of NaOC<\/jats:styled-content>l, whilst in Real Seal SE<\/jats:styled-content>, the highest values were found with a final flush of CHX (all results significant at P<\/jats:italic>\u00a0<\u00a00.001).<\/jats:p><\/jats:sec>Conclusion<\/jats:title>Irrigants had a positive effect on the adhesion of the resin\u2010based sealers, AH<\/jats:styled-content> Plus and Real Seal SE<\/jats:styled-content>, to dentine.<\/jats:p><\/jats:sec>","DOI":"10.1111\/iej.12247","type":"journal-article","created":{"date-parts":[[2014,1,7]],"date-time":"2014-01-07T14:36:04Z","timestamp":1389105364000},"page":"1052-1057","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":4,"title":["Adhesion of resin\u2010based sealers to dentine: an atomic force microscopy study"],"prefix":"10.1111","volume":"47","author":[{"given":"M.","family":"do Prado","sequence":"first","affiliation":[{"name":"Department of Metallurgic and Materials Engineering Federal University of Rio de Janeiro Rio de Janeiro Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D. F.","family":"de Assis","sequence":"additional","affiliation":[{"name":"Department of Metallurgic and Materials Engineering Federal University of Rio de Janeiro Rio de Janeiro Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"B. P. F. A.","family":"Gomes","sequence":"additional","affiliation":[{"name":"Endodontic Division Department of Restorative Dentistry State University of Campinas\u2010 UNICAMP Piracicaba Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R. A.","family":"Sim\u00e3o","sequence":"additional","affiliation":[{"name":"Department of Metallurgic and Materials Engineering Federal University of Rio de Janeiro Rio de Janeiro Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2014,2,13]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.joen.2011.08.014"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.joen.2012.01.002"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1067\/moe.2002.124002"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0167-5729(99)00003-5"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/jbm.820281207"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.joen.2012.10.026"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1097\/00004770-200402000-00013"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jdent.2009.08.005"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.1590\/S0103-64402007000400004"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2591.2001.00410.x"},{"key":"e_1_2_7_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.joen.2009.04.002"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1097\/00004770-200411000-00009"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2591.2010.01848.x"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2591.2012.02073.x"},{"key":"e_1_2_7_16_1","doi-asserted-by":"publisher","DOI":"10.1590\/S0103-64402008000100008"},{"key":"e_1_2_7_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.joen.2012.06.023"},{"key":"e_1_2_7_18_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2591.2012.02111.x"},{"key":"e_1_2_7_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.joen.2012.12.009"},{"key":"e_1_2_7_20_1","doi-asserted-by":"publisher","DOI":"10.1002\/jemt.22153"},{"key":"e_1_2_7_21_1","doi-asserted-by":"publisher","DOI":"10.2209\/tdcpublication.53.1"},{"key":"e_1_2_7_22_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2591.2002.00585.x"},{"key":"e_1_2_7_23_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2591.1995.tb00289.x"},{"key":"e_1_2_7_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tripleo.2010.05.069"},{"key":"e_1_2_7_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.joen.2006.03.020"},{"key":"e_1_2_7_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.joen.2006.09.014"},{"key":"e_1_2_7_27_1","doi-asserted-by":"publisher","DOI":"10.1097\/00004770-200203000-00010"},{"key":"e_1_2_7_28_1","doi-asserted-by":"publisher","DOI":"10.1067\/moe.2002.128962"},{"key":"e_1_2_7_29_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2591.2011.01945.x"},{"key":"e_1_2_7_30_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2591.2002.00569.x"},{"key":"e_1_2_7_31_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.joen.2005.09.014"}],"container-title":["International Endodontic Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fiej.12247","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/iej.12247","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,3]],"date-time":"2023-10-03T08:50:22Z","timestamp":1696323022000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/iej.12247"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,2,13]]},"references-count":30,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2014,11]]}},"alternative-id":["10.1111\/iej.12247"],"URL":"https:\/\/doi.org\/10.1111\/iej.12247","archive":["Portico"],"relation":{},"ISSN":["0143-2885","1365-2591"],"issn-type":[{"type":"print","value":"0143-2885"},{"type":"electronic","value":"1365-2591"}],"subject":[],"published":{"date-parts":[[2014,2,13]]},"assertion":[{"value":"2013-09-10","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2014-01-04","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2014-02-13","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}