{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,8]],"date-time":"2026-03-08T07:58:47Z","timestamp":1772956727696,"version":"3.50.1"},"reference-count":21,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2014,7,24]],"date-time":"2014-07-24T00:00:00Z","timestamp":1406160000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Int Endodontic J"],"published-print":{"date-parts":[[2015,5]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>To evaluate the effectiveness of isopropyl alcohol, saline or distilled water to prevent the precipitate formed between sodium hypochlorite (Na<jats:styled-content style=\"fixed-case\">OC<\/jats:styled-content>l) and chlorhexidine (<jats:styled-content style=\"fixed-case\">CHX<\/jats:styled-content>) and its effect on the bond strength of an epoxy\u2010based sealer in radicular dentine.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methodology<\/jats:title><jats:p>The root canals of 50 extracted human canines (<jats:italic>n<\/jats:italic>\u00a0=\u00a010) were instrumented. In G1, root canals were irrigated with 17% <jats:styled-content style=\"fixed-case\">EDTA<\/jats:styled-content> and 2.5% Na<jats:styled-content style=\"fixed-case\">OC<\/jats:styled-content>l; G2, as G1, except that 2% <jats:styled-content style=\"fixed-case\">CHX<\/jats:styled-content> was used as the final irrigant. In the other groups, intermediate flushes with isopropyl alcohol (G3), saline (G4) or distilled water (G5) were used between Na<jats:styled-content style=\"fixed-case\">OC<\/jats:styled-content>l and <jats:styled-content style=\"fixed-case\">CHX<\/jats:styled-content>. The specimens were submitted to <jats:styled-content style=\"fixed-case\">SEM<\/jats:styled-content> analysis to evaluate the presence of debris and smear layer, in the apical and cervical segments. In sequence, fifty extracted human canines were distributed into five groups (<jats:italic>n<\/jats:italic>\u00a0=\u00a010), similar to the <jats:styled-content style=\"fixed-case\">SEM<\/jats:styled-content> study. After root filling, the roots were sectioned transversally to obtain dentine slices, in the cervical, middle and apical thirds. The root filling was submitted to a push\u2010out bond strength test using an electromechanical testing machine. Statistical analysis was performed using Kruskal\u2013Wallis and Dunn's tests (\u03b1\u00a0=\u00a05%).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>All groups had similar amounts of residue precipitated on the canal walls (<jats:italic>P\u00a0<\/jats:italic>&gt;\u00a00.05). The push\u2010out bond strength values were similar for all groups, independently of the root third evaluated (<jats:italic>P\u00a0<\/jats:italic>&gt;\u00a00.05).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Isopropyl alcohol, saline and distilled water failed to prevent the precipitation of residues on canal walls following the use of Na<jats:styled-content style=\"fixed-case\">OC<\/jats:styled-content>l and <jats:styled-content style=\"fixed-case\">CHX<\/jats:styled-content>. The residues did not interfere with the push\u2010out bond strength of the root filling.<\/jats:p><\/jats:sec>","DOI":"10.1111\/iej.12337","type":"journal-article","created":{"date-parts":[[2014,6,24]],"date-time":"2014-06-24T17:10:52Z","timestamp":1403629852000},"page":"478-483","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":49,"title":["Effectiveness of several solutions to prevent the formation of precipitate due to the interaction between sodium hypochlorite and chlorhexidine and its effect on bond strength of an epoxy\u2010based sealer"],"prefix":"10.1111","volume":"48","author":[{"given":"M. G.","family":"Magro","sequence":"first","affiliation":[{"name":"Department of Restorative Dentistry Araraquara Dental School UNESP \u2010 Univ Estadual Paulista Araraquara PS Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M. C.","family":"Kuga","sequence":"additional","affiliation":[{"name":"Department of Restorative Dentistry Araraquara Dental School UNESP \u2010 Univ Estadual Paulista Araraquara PS Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A. J.","family":"Aranda\u2010Garcia","sequence":"additional","affiliation":[{"name":"Department of Restorative Dentistry Araraquara Dental School UNESP \u2010 Univ Estadual Paulista Araraquara PS Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K. R.","family":"Victorino","sequence":"additional","affiliation":[{"name":"Department of Restorative Dentistry Araraquara Dental School UNESP \u2010 Univ Estadual Paulista Araraquara PS Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G. M.","family":"Ch\u00e1vez\u2010Andrade","sequence":"additional","affiliation":[{"name":"Department of Restorative Dentistry Araraquara Dental School UNESP \u2010 Univ Estadual Paulista Araraquara PS Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G.","family":"Faria","sequence":"additional","affiliation":[{"name":"Department of Restorative Dentistry Araraquara Dental School UNESP \u2010 Univ Estadual Paulista Araraquara PS Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K. C.","family":"Keine","sequence":"additional","affiliation":[{"name":"Department of Restorative Dentistry Araraquara Dental School UNESP \u2010 Univ Estadual Paulista Araraquara PS Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M. V. 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