{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,23]],"date-time":"2026-08-23T15:20:45Z","timestamp":1787498445438,"version":"build-2736575974"},"reference-count":53,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2014,8,27]],"date-time":"2014-08-27T00:00:00Z","timestamp":1409097600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Int Endodontic J"],"published-print":{"date-parts":[[2015,5]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Aim<\/jats:title>\n                    <jats:p>To discuss the clinical and radiological outcome of a revascularization procedure which was completed in a single visit (using sodium hypochlorite 5% as the sole disinfectant) in an immature tooth with a necrotic pulp and apical periodontitis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Summary<\/jats:title>\n                    <jats:p>\n                      A 7\u2010year\u2010old girl was referred in pain following trauma to the maxillary anterior region some 6\u20137\u00a0weeks previously. The maxillary left central incisor tooth was diagnosed with a necrotic pulp and acute apical periodontitis. Under local anaesthesia and rubber dam isolation, an access cavity was prepared. The canal was irrigated with a 5% sodium hypochlorite solution and agitated with an ultrasonic file. A 17%\n                      <jats:styled-content style=\"fixed-case\">EDTA<\/jats:styled-content>\n                      solution was also used for a final rinse. Bleeding was induced into the canal space from the periapical tissues using a K\u2010file. An\n                      <jats:styled-content style=\"fixed-case\">MTA<\/jats:styled-content>\n                      layer\/barrier was placed directly onto the blood clot, and a further layer of\n                      <jats:styled-content style=\"fixed-case\">GC<\/jats:styled-content>\n                      Fuji\n                      <jats:styled-content style=\"fixed-case\">IX<\/jats:styled-content>\n                      cement was placed on top of the\n                      <jats:styled-content style=\"fixed-case\">MTA<\/jats:styled-content>\n                      to restore the access cavity. The tooth was reevaluated at 6\u00a0weeks, 3\u00a0months, 6\u00a0months, 1\u00a0year and 18\u00a0months. The tooth has remained symptom free. Radiographic examination shows progressive thickening of the root canal walls, root lengthening and apical closure.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Key learning points<\/jats:title>\n                    <jats:p>\n                      <jats:list list-type=\"bullet\">\n                        <jats:list-item>\n                          <jats:p>Disinfection with 5% sodium hypochlorite followed by the induction of a blood clot into the root canal space may be sufficient to promote revascularization in certain circumstances.<\/jats:p>\n                        <\/jats:list-item>\n                        <jats:list-item>\n                          <jats:p>A single visit revascularization procedure is a potential treatment option.<\/jats:p>\n                        <\/jats:list-item>\n                      <\/jats:list>\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/iej.12344","type":"journal-article","created":{"date-parts":[[2014,7,25]],"date-time":"2014-07-25T08:57:30Z","timestamp":1406278650000},"page":"484-497","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":49,"title":["Revascularization of an immature tooth with apical periodontitis using a single visit protocol: a case report"],"prefix":"10.1111","volume":"48","author":[{"given":"P.","family":"McCabe","sequence":"first","affiliation":[{"name":"The Oranhill Dental Suite Oranmore, Co. 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