{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,20]],"date-time":"2026-07-20T04:37:40Z","timestamp":1784522260348,"version":"3.55.0"},"reference-count":30,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2015,2,17]],"date-time":"2015-02-17T00:00:00Z","timestamp":1424131200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Int Endodontic J"],"published-print":{"date-parts":[[2016,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>To evaluate the effect of prior application of several intracanal medicaments on the push\u2010out bond strength of ProRoot <jats:styled-content style=\"fixed-case\">MTA<\/jats:styled-content> and Biodentine.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methodology<\/jats:title><jats:p>Sixty freshly extracted maxillary anterior teeth were sectioned below the cementoenamel junction, and the root canals instrumented using rotary files. Thereafter, a parallel post drill was used to obtain a standardized root canal dimension. The roots were randomly assigned into one of the following groups with respect to the intracanal medicament applied: group 1: calcium hydroxide (<jats:styled-content style=\"fixed-case\">CH<\/jats:styled-content>) powder (Merck, Darmstadt, Germany) mixed with distilled water; group 2: a mixture of metronidazole, ciprofloxacin and minocycline (triple antibiotic paste); group 3: a combination of amoxicillin and clavulanic acid (Augmentin; Champs Pharmacy, San Antonio, <jats:styled-content style=\"fixed-case\">TX<\/jats:styled-content>,<jats:styled-content style=\"fixed-case\"> USA<\/jats:styled-content>); group 4: an antibiotic\u2013corticoid compound paste (Ledermix; Riemser, Greifswald, Germany); and group 5: no medicament (control). Following removal of medicaments with instrumentation and irrigation, the roots were cut into 1\u2010mm\u2010thick parallel transverse sections in a coronal\u2010to\u2010apical direction (5 slices\/tooth). Thereafter, the specimens were divided into two subgroups according to the calcium silicate cement applied (<jats:italic>n<\/jats:italic>\u00a0=\u00a030\/group): (i) ProRoot <jats:styled-content style=\"fixed-case\">MTA<\/jats:styled-content> (Dentsply Tulsa Dental, Tulsa, <jats:styled-content style=\"fixed-case\">OK<\/jats:styled-content>,<jats:styled-content style=\"fixed-case\"> USA<\/jats:styled-content>) and (ii) Biodentine (Septodont, Saint\u2010Maur\u2010des\u2010Fosses, France). A push\u2010out test was performed, and the data were analysed statistically using two\u2010way <jats:sc>anova<\/jats:sc> and Tukey's <jats:italic>post hoc<\/jats:italic> test.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Regardless of the type of intracanal medicament used, Biodentine had significantly higher bond strength than <jats:styled-content style=\"fixed-case\">MTA<\/jats:styled-content> (<jats:italic>P<\/jats:italic>\u00a0&lt;\u00a00.05). The highest push\u2010out bond strength results were obtained in <jats:styled-content style=\"fixed-case\">CH<\/jats:styled-content>\u2010treated dentine. Compared with other medicaments, this value was only significantly higher than that of Ledermix (<jats:italic>P<\/jats:italic>\u00a0&lt;\u00a00.05). In both the <jats:styled-content style=\"fixed-case\">MTA<\/jats:styled-content> and Biodentine groups, pairwise comparisons between other medicaments showed similar debonding values (<jats:italic>P<\/jats:italic>\u00a0&gt;\u00a00.05).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Biodentine had a higher bond strength to root canal dentine than ProRoot <jats:styled-content style=\"fixed-case\">MTA<\/jats:styled-content>. Prior <jats:styled-content style=\"fixed-case\">CH<\/jats:styled-content> in distilled water intracanal placement increased the dislodgment resistance of both calcium silicate cements.<\/jats:p><\/jats:sec>","DOI":"10.1111\/iej.12433","type":"journal-article","created":{"date-parts":[[2015,1,29]],"date-time":"2015-01-29T06:10:18Z","timestamp":1422511818000},"page":"184-188","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":57,"title":["Effect of several intracanal medicaments on the push\u2010out bond strength of ProRoot <scp>MTA<\/scp> and Biodentine"],"prefix":"10.1111","volume":"49","author":[{"given":"E.","family":"Nagas","sequence":"first","affiliation":[{"name":"Department of Endodontics Hacettepe University Ankara Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Z. C.","family":"Cehreli","sequence":"additional","affiliation":[{"name":"Department of Pediatric Dentistry Faculty of Dentistry Hacettepe University Ankara Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M. O.","family":"Uyanik","sequence":"additional","affiliation":[{"name":"Department of Endodontics Hacettepe University Ankara Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P. K.","family":"Vallittu","sequence":"additional","affiliation":[{"name":"Department of Biomaterials Science and Turku Clinical Biomaterials Centre \u2010 TCBC Institute of Dentistry University of Turku Turku Finland"},{"name":"City of Turku Welfare Division Oral Health Care Turku Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L. V. J.","family":"Lassila","sequence":"additional","affiliation":[{"name":"Department of Biomaterials Science and Turku Clinical Biomaterials Centre \u2010 TCBC Institute of Dentistry University of Turku Turku Finland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2015,2,17]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.joen.2008.05.006"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1177\/0022034512443068"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1097\/00004770-200404000-00003"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1097\/00004770-200301000-00012"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.joen.2013.12.027"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.joen.2010.06.010"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.joen.2009.06.021"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-9657.2006.00483.x"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/aej.12055"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.joen.2009.09.008"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2591.2003.00735.x"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2591.2005.01037.x"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.joen.2012.11.033"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2591.2011.01924.x"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-9657.1995.tb00500.x"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2591.2008.01490.x"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.1922\/IDJ_2060Kawashima07"},{"key":"e_1_2_6_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.joen.2005.10.065"},{"key":"e_1_2_6_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.joen.2006.06.005"},{"key":"e_1_2_6_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.joen.2013.06.019"},{"key":"e_1_2_6_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0099-2399(06)81095-2"},{"key":"e_1_2_6_23_1","doi-asserted-by":"publisher","DOI":"10.1097\/00004770-200209000-00002"},{"key":"e_1_2_6_24_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2591.1999.00275.x"},{"key":"e_1_2_6_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.joen.2007.01.004"},{"key":"e_1_2_6_26_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2591.2006.01182.x"},{"key":"e_1_2_6_27_1","doi-asserted-by":"publisher","DOI":"10.1097\/00004770-200205000-00001"},{"key":"e_1_2_6_28_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0099-2399(99)80142-3"},{"key":"e_1_2_6_29_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.joen.2009.09.010"},{"key":"e_1_2_6_30_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0099-2399(06)80326-2"},{"key":"e_1_2_6_31_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.don.0000148143.80283.ea"}],"container-title":["International Endodontic Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1111%2Fiej.12433","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/iej.12433","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,24]],"date-time":"2023-09-24T16:22:33Z","timestamp":1695572553000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/iej.12433"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,2,17]]},"references-count":30,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2016,2]]}},"alternative-id":["10.1111\/iej.12433"],"URL":"https:\/\/doi.org\/10.1111\/iej.12433","archive":["Portico"],"relation":{},"ISSN":["0143-2885","1365-2591"],"issn-type":[{"value":"0143-2885","type":"print"},{"value":"1365-2591","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,2,17]]},"assertion":[{"value":"2014-11-01","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2015-01-24","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2015-02-17","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}