{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T13:01:54Z","timestamp":1790686914031,"version":"4.1.0"},"reference-count":46,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2015,4,10]],"date-time":"2015-04-10T00:00:00Z","timestamp":1428624000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Int Endodontic J"],"published-print":{"date-parts":[[2016,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>To evaluate the influence of various predictors on the healing outcome 2\u20136\u00a0years after apical microsurgery (<jats:styled-content style=\"fixed-case\">AMS<\/jats:styled-content>) using <jats:styled-content style=\"fixed-case\">MTA<\/jats:styled-content> as the root\u2010end filling material.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methodology<\/jats:title><jats:p>A total of 90 anterior teeth with asymptomatic persistent periradicular periodontitis of strictly endodontic origin that failed after either nonsurgical or surgical treatment were included. Surgery was completed under local anaesthesia using a standardized clinical protocol. Clinical and radiographic measures as well as the follow\u2010up period were used to determine the healing outcome. For statistical analysis of the predictors, the outcome was dichotomized into healed cases and nonhealed cases. Odds ratios were calculated, and Pearson chi\u2010square or Fisher's exact tests were used to analyse the data.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Clinical and radiographic assessment of <jats:styled-content style=\"fixed-case\">AMS<\/jats:styled-content> revealed that 80% were healed, 14.4% were nonhealed, whilst 5.6% were judged to be uncertain. None of the various predictors investigated had a significant influence on the outcome of <jats:styled-content style=\"fixed-case\">AMS<\/jats:styled-content>.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The results of this clinical study demonstrated that 80% of cases that received apical microsurgery healed when using <jats:styled-content style=\"fixed-case\">MTA<\/jats:styled-content> as the root\u2010end filling material.<\/jats:p><\/jats:sec>","DOI":"10.1111\/iej.12451","type":"journal-article","created":{"date-parts":[[2015,3,26]],"date-time":"2015-03-26T21:38:08Z","timestamp":1427405888000},"page":"245-254","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":61,"title":["The outcome of apical microsurgery using <scp>MTA<\/scp> as the root\u2010end filling material: 2\u2010 to 6\u2010year follow\u2010up study"],"prefix":"10.1111","volume":"49","author":[{"given":"M. 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