{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,9]],"date-time":"2026-10-09T12:45:35Z","timestamp":1791549935548,"version":"4.3.4"},"reference-count":47,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2016,2,22]],"date-time":"2016-02-22T00:00:00Z","timestamp":1456099200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Int Endodontic J"],"published-print":{"date-parts":[[2017,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>To prospectively investigate the clinical and radiographic success rates of pulpotomy in permanent molars with clinical signs and symptoms suggestive of irreversible pulpitis using mineral trioxide aggregate (<jats:styled-content style=\"fixed-case\">MTA<\/jats:styled-content>) as a pulp dressing agent.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methodology<\/jats:title><jats:p>Sixteen patients with 23 restorable permanent molars exhibiting signs and symptoms indicative of irreversible pulpitis were enrolled. A standardized operative procedure was followed for all participants. All teeth were isolated with a dental dam and caries was removed, and then, pulpotomy performed with a sterile round and\/or flame shape diamond burs. Haemostasis was achieved with 5% sodium hypochlorite (Na<jats:styled-content style=\"fixed-case\">OC<\/jats:styled-content>l). A mixture of <jats:styled-content style=\"fixed-case\">MTA<\/jats:styled-content> was placed against the wound, and a moistened cotton pellet was placed over the <jats:styled-content style=\"fixed-case\">MTA<\/jats:styled-content>. Teeth were temporized with a glass\u2013ionomer restoration. Three to ten days later, the interim restoration was removed and setting of <jats:styled-content style=\"fixed-case\">MTA<\/jats:styled-content> was evaluated. Teeth were restored with stainless steel crowns. Follow\u2010up evaluations were scheduled at 3, 6, 12\u00a0months and annually thereafter. Descriptive statistics were used to assess outcomes.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>The age of patients at time of pulpotomy ranged between 7.6 and 13.6\u00a0years (mean\u00a0=\u00a010.7\u00b1\u00a01.7\u00a0yrs). The majority of teeth (91%) had clinical signs and symptoms consistent with a diagnosis of symptomatic irreversible pulpitis and symptomatic apical periodontitis (78%). The follow\u2010up examination period ranged from 18.9 to 73.6\u00a0months. Clinically and radiographically, all pulpotomies were considered successful at the end of the follow\u2010up period. Radiographically, a hard tissue barrier was noticed in 13 (57%) teeth.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>In children, <jats:styled-content style=\"fixed-case\">MTA<\/jats:styled-content> was associated with high clinical and radiographic success as a pulpotomy agent in permanent teeth with clinical signs and symptoms suggestive of irreversible pulpitis.<\/jats:p><\/jats:sec>","DOI":"10.1111\/iej.12614","type":"journal-article","created":{"date-parts":[[2016,2,4]],"date-time":"2016-02-04T12:01:31Z","timestamp":1454587291000},"page":"126-134","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":123,"title":["Mineral trioxide aggregate pulpotomy for permanent molars with clinical signs indicative of irreversible pulpitis: a preliminary study"],"prefix":"10.1111","volume":"50","author":[{"given":"M. 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