{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T08:06:08Z","timestamp":1790755568540,"version":"4.1.0"},"reference-count":35,"publisher":"Wiley","issue":"10","license":[{"start":{"date-parts":[[2016,11,28]],"date-time":"2016-11-28T00:00:00Z","timestamp":1480291200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/100007465","name":"Universitetet i Troms\u00f8","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100007465","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Int Endodontic J"],"published-print":{"date-parts":[[2017,10]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>The aim of this multicentre, parallel\u2010group randomized clinical trial was to compare the effectiveness of mineral trioxide aggregate (<jats:styled-content style=\"fixed-case\">MTA<\/jats:styled-content>) and a conventional calcium hydroxide liner (<jats:styled-content style=\"fixed-case\">CH<\/jats:styled-content>) as direct pulp capping materials in adult molars with carious pulpal exposure.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methodology<\/jats:title><jats:p>Seventy adults aged 18\u201355\u00a0years were randomly allocated to two parallel arms: <jats:styled-content style=\"fixed-case\">MTA<\/jats:styled-content> (White ProRoot, Dentsply, Tulsa Dental, Tulsa, <jats:styled-content style=\"fixed-case\">OK<\/jats:styled-content>,<jats:styled-content style=\"fixed-case\"> USA<\/jats:styled-content>;<jats:italic> n<\/jats:italic>\u00a0=\u00a033) and <jats:styled-content style=\"fixed-case\">CH<\/jats:styled-content> (Dycal<jats:sup>\u00ae<\/jats:sup>, Dentsply DeTrey GmbH, Konstanz, Germany; <jats:italic>n<\/jats:italic>\u00a0=\u00a037). The teeth were temporized for 1\u00a0week with glass\u2013ionomer (Fuji <jats:styled-content style=\"fixed-case\">IX<\/jats:styled-content>,<jats:styled-content style=\"fixed-case\"> GC<\/jats:styled-content> Corp, Tokyo, Japan) and then permanently restored with a composite resin. The subjects were followed up after 1\u00a0week and at six, 12, 24 and 36\u00a0months. The primary outcome was the survival of the capped pulps, and the secondary outcome was postoperative pain after 1\u00a0week. Survival was defined as a nonsymptomatic tooth that responded to sensibility testing and did not exhibit periapical changes on radiograph. At each check\u2010up, the pulp was tested for sensibility and a periapical radiograph was taken (excluding the radiographs taken at the 1\u2010week follow\u2010up). Kaplan\u2013Meier survival analysis and log\u2010rank test were used to assess the significant difference in the survival curves between groups. Chi\u2010square test was used to assess the association between the materials and preoperative and postoperative pain.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>At 36\u00a0months, the Kaplan\u2013Meier survival analysis showed a cumulative estimate rate of 85% for the <jats:styled-content style=\"fixed-case\">MTA<\/jats:styled-content> group and 52% for the <jats:styled-content style=\"fixed-case\">CH<\/jats:styled-content> group (<jats:italic>P<\/jats:italic>\u00a0=\u00a00.006). There was no significant association between the capping material and postoperative pain.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Mineral trioxide aggregate performed more effectively than a conventional <jats:styled-content style=\"fixed-case\">CH<\/jats:styled-content> liner as a direct pulp capping material in molars with carious pulpal exposure in adult patients. This study has been registered at ClinicalTrials.gov, number <jats:styled-content style=\"fixed-case\">NCT<\/jats:styled-content>01224925.<\/jats:p><\/jats:sec>","DOI":"10.1111\/iej.12719","type":"journal-article","created":{"date-parts":[[2016,11,7]],"date-time":"2016-11-07T15:01:55Z","timestamp":1478530915000},"page":"924-932","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":139,"title":["Capping carious exposures in adults: a randomized controlled trial investigating mineral trioxide aggregate versus calcium hydroxide"],"prefix":"10.1111","volume":"50","author":[{"given":"R.","family":"Kundzina","sequence":"first","affiliation":[{"name":"Department of Clinical Dentistry Faculty of Health Sciences UiT, The Arctic University of Norway Tromso Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L.","family":"Stangvaltaite","sequence":"additional","affiliation":[{"name":"Department of Clinical Dentistry Faculty of Health Sciences UiT, The Arctic University of Norway Tromso Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H. 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