{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,17]],"date-time":"2025-12-17T17:40:19Z","timestamp":1765993219778,"version":"3.37.3"},"reference-count":41,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2017,9,25]],"date-time":"2017-09-25T00:00:00Z","timestamp":1506297600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Int Endodontic J"],"published-print":{"date-parts":[[2018,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>To achieve a better understanding of a calcified extraradicular deposit on the apical root surfaces of a mandibular first molar associated with a radicular cyst and a sinus tract. A multimodular approach was applied using a combination of multiple investigation methods.<\/jats:p><\/jats:sec><jats:sec><jats:title>Summary<\/jats:title><jats:p>This case report presents a mandibular first molar with a calcified extraradicular deposit on the apical root surfaces of both roots. An apical periodontitis lesion was present and a sinus tract served as the only communication with the oral cavity. Diagnosis and treatment planning were based on clinical, radiographic (two\u2010 and three\u2010dimensional) and ultrasound examination. The tooth was further analysed after extraction using microscopic imaging, nano\u2010computed tomography (nano\u2010CT), hard\u2010 and soft tissue histology and electron probe microanalysis. This multimodular approach revealed the calculus\u2010like appearance and mineral composition of the extraradicular deposit. Multiple hypotheses about its aetiology are discussed.<\/jats:p><\/jats:sec><jats:sec><jats:title>Key learning points<\/jats:title><jats:p>\n<jats:list list-type=\"bullet\">\n\n<jats:list-item><jats:p>Calcified extraradicular deposits can develop on the apical root surfaces of teeth with apical periodontitis in association with a radicular cyst and sinus tract.<\/jats:p><\/jats:list-item>\n\n<jats:list-item><jats:p>A sinus tract can serve as the only communication between the apical lesion and the oral cavity whilst no periodontal defects are present.<\/jats:p><\/jats:list-item>\n\n<jats:list-item><jats:p>The interplay of intra\u2010oral radiography, high resolution CBCT, nano\u2010CT, hard tissue histology and EPMA can reveal the calculus\u2010like appearance and composition of the extraradicular deposit.<\/jats:p><\/jats:list-item>\n\n<jats:list-item><jats:p>Calcified extraradicular deposits appear hyperechoic on ultrasound imaging and can lead to the occurrence of twinkling artefacts due to their rough mineralized surface.<\/jats:p><\/jats:list-item>\n<\/jats:list>\n<\/jats:p><\/jats:sec>","DOI":"10.1111\/iej.12855","type":"journal-article","created":{"date-parts":[[2017,9,2]],"date-time":"2017-09-02T14:22:40Z","timestamp":1504362160000},"page":"375-385","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":10,"title":["Multimodular assessment of a calcified extraradicular deposit on the root surfaces of a mandibular molar"],"prefix":"10.1111","volume":"51","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5420-133X","authenticated-orcid":false,"given":"E.","family":"Petitjean","sequence":"first","affiliation":[{"name":"Department of Oral Health Sciences University Hospitals Leuven KU Leuven Leuven Belgium"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Mavridou","sequence":"additional","affiliation":[{"name":"Department of Oral Health Sciences University Hospitals Leuven KU Leuven Leuven Belgium"},{"name":"BIOMAT Department of Oral Health Sciences University Hospitals Leuven KU Leuven Leuven Belgium"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"X.","family":"Li","sequence":"additional","affiliation":[{"name":"BIOMAT Department of Oral Health Sciences University Hospitals Leuven KU Leuven Leuven Belgium"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E.","family":"Hauben","sequence":"additional","affiliation":[{"name":"Department of Imaging and Pathology Translational Cell &amp; 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