{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T10:55:42Z","timestamp":1791888942010,"version":"4.3.4"},"reference-count":45,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2018,2,27]],"date-time":"2018-02-27T00:00:00Z","timestamp":1519689600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100004035","name":"Jordan University of Science and Technology","doi-asserted-by":"publisher","award":["156\/2016"],"award-info":[{"award-number":["156\/2016"]}],"id":[{"id":"10.13039\/501100004035","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Int Endodontic J"],"published-print":{"date-parts":[[2018,8]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>To assess the outcome of full pulpotomy using Biodentine in permanent teeth with carious exposures and symptoms indicative of irreversible pulpitis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methodology<\/jats:title><jats:p>Sixty\u2010four permanent molar teeth with symptomatic vital pulps in 52 patients aged 19\u201369\u00a0years were included. Preoperative pulpal and periapical diagnosis was established. After informed consent, the tooth was anaesthetized, isolated using rubber dam and disinfected with 5% Na<jats:styled-content style=\"fixed-case\">OC<\/jats:styled-content>l before caries excavation; subsequently, the pulp was amputated to the level of the canal orifices. Haemostasis was achieved, and a 3\u2010mm layer of Biodentine (Septodont, Saint\u2010Maur\u2010des\u2010Fosses, France) was placed as the pulpotomy agent. Resin\u2010modified glass\u2013ionomer liner was placed and the tooth restored with either resin composite or amalgam, and a postoperative periapical radiograph exposed. Clinical and radiographic evaluation was completed at 6\u00a0months and 1\u00a0year postoperatively. Pain levels were scored preoperatively and 2\u00a0days post\u2010treatment.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Clinical signs and symptoms indicative of irreversible pulpitis were established in all teeth, and periapical rarefaction was present in nine teeth. After 2\u00a0days, 93.8% reported complete relief of pain. At 6\u00a0months, 63 of 64 attended recall with 98.4% clinical and radiographic success. At 1\u00a0year, 59 of 63 attended recall, with 100% clinical and 98.4 radiographic success. Seven of eight cases with periapical rarefaction who attended recall had improvement in the periapical index (<jats:styled-content style=\"fixed-case\">PAI<\/jats:styled-content>) score. A hard tissue barrier was detected radiographically in four cases.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Full pulpotomy using Biodentine was a successful treatment option for cariously exposed pulps in mature permanent molar teeth with clinical signs and symptoms indicative of irreversible pulpitis, up to 1\u00a0year.<\/jats:p><\/jats:sec>","DOI":"10.1111\/iej.12903","type":"journal-article","created":{"date-parts":[[2018,2,3]],"date-time":"2018-02-03T14:56:40Z","timestamp":1517669800000},"page":"819-828","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":160,"title":["Outcome of full pulpotomy using Biodentine in adult patients with symptoms indicative of irreversible pulpitis"],"prefix":"10.1111","volume":"51","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3233-8850","authenticated-orcid":false,"given":"N. 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