{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,4]],"date-time":"2026-06-04T10:39:27Z","timestamp":1780569567283,"version":"3.54.1"},"reference-count":21,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2018,3,14]],"date-time":"2018-03-14T00:00:00Z","timestamp":1520985600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Int Endodontic J"],"published-print":{"date-parts":[[2018,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>To report a case of reparative bone\u2010like tissue formation in the tooth of a patient with systemic sclerosis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Summary<\/jats:title><jats:p>A 58\u2010year\u2010old Japanese female patient with systemic sclerosis was referred because of tooth fracture. Cone beam computerized tomography (<jats:styled-content style=\"fixed-case\">CBCT<\/jats:styled-content>) revealed multiple root resorption and the unclear transition from alveolar bone to root profile. A sample from a fractured tooth was analysed histologically. Haematoxylin and eosin\u2010stained sections revealed the irregular replacement of pulp and dentine by bone\u2010like tissue. Calcinosis was noted in various parts of the body and a histological analysis identified it as dystrophic calcification on sclerosed fibrous connective tissue. Bite force and the occlusal area were markedly weaker than the means for female of the same age.<\/jats:p><\/jats:sec><jats:sec><jats:title>Key learning points<\/jats:title><jats:p>\n<jats:list list-type=\"bullet\">\n\n<jats:list-item>\n<jats:p><jats:styled-content style=\"fixed-case\">CBCT<\/jats:styled-content> may be more useful than dental radiography for diagnosing multiple root resorption in systemic sclerosis patients.<\/jats:p>\n<\/jats:list-item>\n\n<jats:list-item>\n<jats:p>When systemic sclerosis patients have calcinosis, their root status must be examined carefully.<\/jats:p>\n<\/jats:list-item>\n\n<jats:list-item>\n<jats:p>When root resorption is present in systemic sclerosis patients, reparative bone\u2010like tissue formation in teeth needs to be taken into account prior to the initiation of dental treatment.<\/jats:p>\n<\/jats:list-item>\n<\/jats:list>\n<\/jats:p><\/jats:sec>","DOI":"10.1111\/iej.12914","type":"journal-article","created":{"date-parts":[[2018,2,26]],"date-time":"2018-02-26T15:51:29Z","timestamp":1519660289000},"page":"1059-1066","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":9,"title":["Reparative bone\u2010like tissue formation in the tooth of a systemic sclerosis patient"],"prefix":"10.1111","volume":"51","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4281-3216","authenticated-orcid":false,"given":"S.","family":"Matsuda","sequence":"first","affiliation":[{"name":"Department of Periodontal Medicine, Applied Life Sciences Institute of Biomedical &amp; 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