{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,21]],"date-time":"2026-08-21T13:41:06Z","timestamp":1787319666788,"version":"build-2736575974"},"reference-count":38,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2018,10,17]],"date-time":"2018-10-17T00:00:00Z","timestamp":1539734400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"American Academy of Orofacial Pain"},{"name":"University of Minnesota Lasby Visiting Fellowship"},{"name":"Newcastle University internal funds"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Int Endodontic J"],"published-print":{"date-parts":[[2019,3]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Aim<\/jats:title>\n                    <jats:p>\n                      To develop and preliminarily evaluate a new screening instrument for atypical odontalgia (\n                      <jats:styled-content style=\"fixed-case\">AO<\/jats:styled-content>\n                      ) or persistent dentoalveolar pain disorder (\n                      <jats:styled-content style=\"fixed-case\">PDAP<\/jats:styled-content>\n                      ). To evaluate the instrument's performance in detecting\n                      <jats:styled-content style=\"fixed-case\">AO<\/jats:styled-content>\n                      \/\n                      <jats:styled-content style=\"fixed-case\">PDAP<\/jats:styled-content>\n                      amongst a heterogeneous group of orofacial pain conditions and pain\u2010free controls and empirically compare its performance with an established neuropathic screening instrument (S\u2010\n                      <jats:styled-content style=\"fixed-case\">LANSS<\/jats:styled-content>\n                      ), which is the best available standard.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      The study design was cross\u2010sectional; subjects recruited included a convenience sample of pain\u2010free controls (\n                      <jats:italic>n<\/jats:italic>\n                      \u00a0=\u00a021) and four groups of orofacial pain conditions:\n                      <jats:styled-content style=\"fixed-case\">AO<\/jats:styled-content>\n                      \/\n                      <jats:styled-content style=\"fixed-case\">PDAP<\/jats:styled-content>\n                      (\n                      <jats:italic>n<\/jats:italic>\n                      \u00a0=\u00a022); trigeminal neuralgia (\n                      <jats:italic>n<\/jats:italic>\n                      \u00a0=\u00a021); temporomandibular disorder (\n                      <jats:italic>n<\/jats:italic>\n                      \u00a0=\u00a041); and acute dental pain (\n                      <jats:italic>n<\/jats:italic>\n                      \u00a0=\u00a041). The instrument's internal reliability and factor structure were examined alongside its sensitivity and specificity and\n                      <jats:styled-content style=\"fixed-case\">ROC<\/jats:styled-content>\n                      \u2010determined threshold score.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      The 9\n                      <jats:styled-content style=\"fixed-case\">AO<\/jats:styled-content>\n                      \/\n                      <jats:styled-content style=\"fixed-case\">PDAP<\/jats:styled-content>\n                      \u2010specific items were found to moderately correlate with the S\u2010\n                      <jats:styled-content style=\"fixed-case\">LANSS<\/jats:styled-content>\n                      (\n                      <jats:italic>r<\/jats:italic>\n                      \u00a0=\u00a00.58;\n                      <jats:italic>P<\/jats:italic>\n                      \u00a0&lt;\u00a00.01). The 14\u2010items of the full instrument were examined using exploratory factor analysis and reduced to ten items in a two\u2010factor structure that explained 96% of the variance. This 10\u2010item final instrument had a\n                      <jats:styled-content style=\"fixed-case\">ROC<\/jats:styled-content>\n                      area of 0.77 (95%\n                      <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>\n                      : 0.67; 0.88), sensitivity of 77% (95%\n                      <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>\n                      : 55; 92%), and specificity of 69% (95%\n                      <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>\n                      : 60; 77%) with an intentionally higher false\u2010positive rate than false\u2010negative rate. In contrast, the S\u2010\n                      <jats:styled-content style=\"fixed-case\">LANSS<\/jats:styled-content>\n                      exhibited sensitivity of 32% (95%\n                      <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>\n                      : 14;55%) and specificity of 78% (95%\n                      <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>\n                      : 70;85%) with less optimal false\u2010positive versus false\u2010negative rates.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>\n                      This preliminary study confirms the new screening instrument for\n                      <jats:styled-content style=\"fixed-case\">AO<\/jats:styled-content>\n                      \/\n                      <jats:styled-content style=\"fixed-case\">PDAP<\/jats:styled-content>\n                      merits progression to field testing.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/iej.13017","type":"journal-article","created":{"date-parts":[[2018,9,19]],"date-time":"2018-09-19T06:50:13Z","timestamp":1537339813000},"page":"279-287","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":6,"title":["Development and preliminary evaluation of a new screening instrument for atypical odontalgia and persistent dentoalveolar pain disorder"],"prefix":"10.1111","volume":"52","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5968-1969","authenticated-orcid":false,"given":"J.","family":"Durham","sequence":"first","affiliation":[{"name":"Centre for Oral Health Research School of Dental Sciences Newcastle upon Tyne UK"},{"name":"Institute of Health &amp; Society Newcastle University Newcastle upon Tyne UK"},{"name":"Dental Hospital Newcastle\u2010Upon\u2010Tyne Hospitals\u2019 NHS Foundation Trust Newcastle upon Tyne UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S. 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