{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,13]],"date-time":"2026-09-13T07:13:21Z","timestamp":1789283601598,"version":"build-2803163510"},"reference-count":36,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2020,6,15]],"date-time":"2020-06-15T00:00:00Z","timestamp":1592179200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Int Endodontic J"],"published-print":{"date-parts":[[2020,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>This randomized, prospective, controlled trial assessed the effect of occlusal reduction on post\u2010treatment endodontic pain and medication intake following root canal treatment of mandibular posterior teeth with symptomatic irreversible pulpitis with sensitivity to percussion treated in two visits.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methodology<\/jats:title><jats:p>Three hundred and eight patients were randomly assigned into two equal groups according to whether occlusal reduction was done or not (<jats:italic>n\u00a0=\u00a0<\/jats:italic>154). For all patients, root canal treatment was carried out in two visits without intracanal medication. Patients assessed their pain using the 0\u201310 numerical rating scale (NRS) 6, 12, 24 and 48\u00a0h after the first visit (post\u2010instrumentation) and 6 and 12\u00a0h following root canal filling (post\u2010obturation). Patients, also, recorded their medication intake (sham or analgesic), post\u2010instrumentation and post\u2010obturation; patients initially received a sham capsule, but, if pain persisted, an analgesic was prescribed. Data were analysed using Mann\u2013Whitney <jats:italic>U<\/jats:italic>\u2010test, Friedman\u2019s test, Wilcoxon\u2019s rank test and chi\u2010square (<jats:italic>\u03c7<jats:sup>2<\/jats:sup><\/jats:italic>) test. The relative risk (RR) and its 95% confidence interval (CI) were calculated for binary data.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Occlusal reduction was associated with lower pain intensity than no occlusal reduction at 12 and 24\u00a0h post\u2010instrumentation (<jats:italic>P<\/jats:italic>\u00a0&lt;\u00a00.05). Pain intensity significantly and gradually decreased with both groups at all post\u2010instrumentation and post\u2010obturation time\u2010points compared to preoperative pain (<jats:italic>P<\/jats:italic>\u00a0&lt;\u00a00.05). The RR of moderate\u2010to\u2010severe pain was 0.61 (95% CI: 0.41, 0.91) 12\u00a0h post\u2010instrumentation, and the RR of pain incidence, regardless of its level, was 0.75 (95% CI: 0.61, 0.92) 24\u00a0h post\u2010instrumentation. There was no significant difference in medication intake (sham or analgesic) between groups (<jats:italic>P\u00a0<\/jats:italic>&gt;\u00a00.05).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Occlusal reduction was effective in reducing the intensity of postoperative pain 12\u00a0h and 24\u00a0h after root canal instrumentation in the first visit in patients with symptomatic irreversible pulpitis with sensitivity to percussion. Occlusal reduction lowered the risk of moderate\u2010to\u2010severe pain by about 40% 12\u00a0h post\u2010instrumentation and the overall risk of pain by 25% 24\u00a0h post\u2010instrumentation; yet, it did not affect medication intake.<\/jats:p><\/jats:sec>","DOI":"10.1111\/iej.13328","type":"journal-article","created":{"date-parts":[[2020,5,17]],"date-time":"2020-05-17T18:15:27Z","timestamp":1589739327000},"page":"1170-1180","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":16,"title":["Post\u2010treatment endodontic pain following occlusal reduction in mandibular posterior teeth with symptomatic irreversible pulpitis and sensitivity to percussion: a single\u2010centre randomized controlled trial"],"prefix":"10.1111","volume":"53","author":[{"given":"Y. E.","family":"Ahmed","sequence":"first","affiliation":[{"name":"Department of Endodontics Faculty of Dentistry Cairo University Cairo Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5350-6772","authenticated-orcid":false,"given":"R. S.","family":"Emara","sequence":"additional","affiliation":[{"name":"Department of Endodontics Faculty of Dentistry Cairo University Cairo Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S. M.","family":"Sarhan","sequence":"additional","affiliation":[{"name":"Department of Endodontics Faculty of Dentistry Cairo University Cairo Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R. M.","family":"El Boghdadi","sequence":"additional","affiliation":[{"name":"Department of Endodontics Faculty of Dentistry Cairo University Cairo Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M. A. 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