{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,15]],"date-time":"2026-09-15T12:09:12Z","timestamp":1789474152294,"version":"build-2803163510"},"reference-count":31,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[2020,10,17]],"date-time":"2020-10-17T00:00:00Z","timestamp":1602892800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Int Endodontic J"],"published-print":{"date-parts":[[2021,2]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>To compare the effect of two calcium silicate\u2010based (Endoseal MTA and EndoSequence BC Sealer) and an epoxy resin\u2010based (AH Plus) root canal sealer on postoperative pain following single\u2010visit root canal treatment on molar teeth.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methodology<\/jats:title><jats:p>Patients (<jats:italic>n<\/jats:italic>\u00a0=\u00a090) having one first or second molar tooth diagnosed with asymptomatic irreversible pulpitis were randomly divided into three groups according to the sealer used (<jats:italic>n<\/jats:italic>\u00a0=\u00a030) and were treated by two endodontists having at least 10\u00a0years of experience. All patients received a single\u2010visit root canal treatment. After the treatments, postoperative pain scores and analgesic intake were recorded at 6, 12, 24 and 48\u00a0h, and 3, 4, 5, 6 and 7\u00a0days. The data were analysed statistically using non\u2010parametric Kruskal\u2013Wallis tests (for the comparisons of the age and VAS scores), Friedman tests (for the assessments of the changes in pain scores over time), chi\u2010squared tests (for the comparisons of categorical variables) and Spearman\u2019s correlation test (for the correlation assessments of the age and gender factors with postoperative pain; \u03b1\u00a0=\u00a00.05).<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>There were no significant differences amongst the groups in terms of postoperative pain at any time\u2010points assessed (<jats:italic>P<\/jats:italic>\u00a0&gt;\u00a00.05) nor for analgesic intake of patients amongst the groups (<jats:italic>P<\/jats:italic>\u00a0&gt;\u00a00.05). Analgesic intake decreased significantly after 12\u00a0h in all groups (<jats:italic>P<\/jats:italic>\u00a0&lt;\u00a00.05).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>The sealers tested in this study were associated with similar levels of postoperative pain and were associated with a similar intake of analgesics.<\/jats:p><\/jats:sec>","DOI":"10.1111\/iej.13411","type":"journal-article","created":{"date-parts":[[2020,9,25]],"date-time":"2020-09-25T16:50:21Z","timestamp":1601052621000},"page":"190-197","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":47,"title":["The effect of two calcium silicate\u2010based and one epoxy resin\u2010based root canal sealer on postoperative pain: a randomized controlled 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