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This review aims to update the present status on the endodontic management of traumatic injuries to permanent teeth and to identify relevant research areas that could contribute to an improvement in diagnosis and treatment of traumatized permanent teeth. Future research should pay greater attention to (1) diagnostic methods to assess the perfusion of the pulp and enhance detection of tooth cracks and initial signs of root resorption; (2) improved materials for vital pulp treatment; (3) studies focusing on type and duration of splinting after root fractures; (4) antiresorptive intracanal medication in case of posttraumatic pulp necrosis and infection\u2010related resorption and (5) long\u2010term data on the apical barrier technique compared to revitalization.<\/jats:p>","DOI":"10.1111\/iej.13672","type":"journal-article","created":{"date-parts":[[2021,12,4]],"date-time":"2021-12-04T13:29:30Z","timestamp":1638624570000},"page":"1003-1019","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":19,"title":["Present status and future directions: Endodontic management of traumatic injuries to permanent teeth"],"prefix":"10.1111","volume":"55","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9402-8121","authenticated-orcid":false,"given":"Gabriel","family":"Krastl","sequence":"first","affiliation":[{"name":"Department of Conservative Dentistry and Periodontology Center of Dental Traumatology University Hospital of W\u00fcrzburg  W\u00fcrzburg Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Roland","family":"Weiger","sequence":"additional","affiliation":[{"name":"Department of Periodontology, Endodontology and Cariology Center of Dental Traumatology University Center for Dental Medicine UZB University of Basel  Basel Switzerland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kurt","family":"Ebeleseder","sequence":"additional","affiliation":[{"name":"University Clinic of Dental Medicine and Oral Health Medical University Graz  Graz Austria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kerstin","family":"Galler","sequence":"additional","affiliation":[{"name":"Department of Conservative Dentistry and Periodontology University Hospital Erlangen Friedrich\u2010Alexander\u2010University Erlangen\u2010N\u00fcrnberg (FAU)  Erlangen Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2021,12,22]]},"reference":[{"key":"e_1_2_22_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/edt.12553"},{"key":"e_1_2_22_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/iej.12611"},{"key":"e_1_2_22_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-9657.2012.01125.x"},{"key":"e_1_2_22_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-9657.1986.tb00118.x"},{"key":"e_1_2_22_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-9657.1989.tb00348.x"},{"key":"e_1_2_22_7_1","volume-title":"Pulpal healing after tooth luxation and root fractures in the permanent dentition","author":"Andreasen F.M.","year":"1995"},{"key":"e_1_2_22_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-9657.1988.tb00323.x"},{"key":"e_1_2_22_9_1","first-page":"372","volume-title":"Textbok & Colour atlas of traumatic injuries to the teeth","author":"Andreasen F.M.","year":"2007"},{"key":"e_1_2_22_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.joen.2014.11.015"},{"key":"e_1_2_22_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-9657.1985.tb00583.x"},{"key":"e_1_2_22_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-9657.1986.tb00133.x"},{"key":"e_1_2_22_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-9657.1987.tb00611.x"},{"key":"e_1_2_22_14_1","first-page":"273","article-title":"Luxation of permanent teeth due to trauma. 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