{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,2]],"date-time":"2026-10-02T17:32:10Z","timestamp":1790962330171,"version":"4.1.0"},"reference-count":60,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2022,11,22]],"date-time":"2022-11-22T00:00:00Z","timestamp":1669075200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Int Endodontic J"],"published-print":{"date-parts":[[2023,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>This randomized clinical trial aimed to evaluate and compare the effect of mineral trioxide aggregate (MTA)\u2010based bioceramic\u2010 and resin\u2010based sealers on the incidence and intensity of post\u2010obturation pain and treatment outcome in asymptomatic vital molar teeth in single\u2010visit root canal treatment.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methodology<\/jats:title><jats:p>One hundred asymptomatic mandibular molar teeth with vital pulp were randomly assigned into two groups according to the sealer used: MTA Fillapex or AH Plus sealer. WaveOne Gold instruments were used for root canal preparations. Root canals were obturated with WaveOne Gold gutta\u2010percha cones corresponding in size and taper to the last instrument used. MTA Fillapex was used in the first group and AH Plus was used in the second group as the root canal sealer. The effects of age, gender, tooth types and the level of root canal filling on the treatment outcome were evaluated after 1 and 2\u2009years. Postoperative pain at 6, 12, 24, 48, 72\u2009h, 4, 5, 6, 7 and 30\u2009days after root canal treatment was measured with the Numerical Rating Scale. Chi\u2010square test was used for the treatment outcome and Mann\u2013Whitney <jats:italic>U<\/jats:italic>, chi\u2010Square and Spearman correlation analyses were used for postoperative pain. <jats:italic>\u03b1<\/jats:italic>\u00a0=\u00a0.05 was the level of significance.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Twelve patients did not complete the 2\u2010year follow\u2010up and the study finished with 88 patients. In the MTA Fillapex group 41 correct, one short, two extruded, and in the AH Plus group 40 correct, one short and three extruded root canal fillings were detected. No significant differences were observed between the first\u2010 and second\u2010year treatment outcomes between the groups (<jats:italic>p<\/jats:italic>\u2009&gt;\u2009.05).There was no association between age, gender, tooth number, root canal filling length and the treatment success in all evaluated teeth (<jats:italic>p<\/jats:italic>\u2009&gt;\u2009.05). The differences between the groups in terms of postoperative pain incidence and intensity at all time\u2010points were not significant (<jats:italic>p<\/jats:italic>\u2009&gt;\u2009.05). There was no correlation between the age and postoperative pain (<jats:italic>p<\/jats:italic>\u2009&gt;\u2009.05), but pain was statistically higher in women (<jats:italic>p<\/jats:italic>\u2009&lt;\u2009.05).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Mineral trioxide aggregate Fillapex showed similar success rate and post\u2010obturation pain incidence and intensity as AH Plus sealer and can be used as a root canal sealer in asymptomatic mandibular molars with irreversible pulpitis.<\/jats:p><\/jats:sec>","DOI":"10.1111\/iej.13870","type":"journal-article","created":{"date-parts":[[2022,11,17]],"date-time":"2022-11-17T08:14:11Z","timestamp":1668672851000},"page":"318-330","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":39,"title":["The effect of two different root canal sealers on treatment outcome and post\u2010obturation pain in single\u2010visit root canal treatment: A prospective randomized clinical trial"],"prefix":"10.1111","volume":"56","author":[{"given":"Melis","family":"Co\u015far","sequence":"first","affiliation":[{"name":"Department of Endodontology, School of Dentistry Ege University  Izmir Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7327-1010","authenticated-orcid":false,"given":"G\u00f6zde","family":"Kandemir Demirci","sequence":"additional","affiliation":[{"name":"Department of Endodontology, School of Dentistry Ege University  Izmir Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6714-4282","authenticated-orcid":false,"given":"Mehmet Kemal","family":"\u00c7al\u0131\u015fkan","sequence":"additional","affiliation":[{"name":"Department of Endodontology, School of Dentistry Ege University  Izmir Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2022,11,22]]},"reference":[{"key":"e_1_2_12_2_1","doi-asserted-by":"publisher","DOI":"10.1155\/2016\/9753210"},{"key":"e_1_2_12_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jdent.2015.12.002"},{"key":"e_1_2_12_4_1","volume-title":"Glossary of endodontic terms","author":"American Association of Endodontists","year":"2020"},{"key":"e_1_2_12_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00784-013-1003-6"},{"key":"e_1_2_12_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/iej.13411"},{"key":"e_1_2_12_7_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00784-018-2721-6"},{"key":"e_1_2_12_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.joen.2011.07.005"},{"key":"e_1_2_12_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.joen.2012.02.029"},{"key":"e_1_2_12_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/iej.13629"},{"key":"e_1_2_12_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1747-4477.2012.00370.x"},{"key":"e_1_2_12_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.joen.2018.02.019"},{"key":"e_1_2_12_13_1","doi-asserted-by":"publisher","DOI":"10.1136\/ard.37.4.378"},{"key":"e_1_2_12_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.joen.2021.05.008"},{"key":"e_1_2_12_15_1","doi-asserted-by":"publisher","DOI":"10.1590\/1807-3107bor-2020.vol34.0069"},{"key":"e_1_2_12_16_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-0039-3399457"},{"key":"e_1_2_12_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.joen.2017.08.007"},{"key":"e_1_2_12_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.joen.2008.11.006"},{"key":"e_1_2_12_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.joen.2010.04.012"},{"key":"e_1_2_12_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.joen.2018.02.010"},{"key":"e_1_2_12_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jdent.2019.103181"},{"key":"e_1_2_12_22_1","doi-asserted-by":"publisher","DOI":"10.1067\/moe.2001.122822"},{"key":"e_1_2_12_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/B978-0-323-06489-7.00010-2"},{"key":"e_1_2_12_24_1","doi-asserted-by":"publisher","DOI":"10.4103\/0972-0707.153054"},{"key":"e_1_2_12_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.joen.2017.11.011"},{"key":"e_1_2_12_26_1","first-page":"e144","article-title":"Comparative evaluation of postoperative pain and periapical healing after root canal treatment using three different base endodontic sealers \u2013 a randomized control clinical trial","volume":"14","author":"Khandelwal A.","year":"2022","journal-title":"Journal of Clinical and Experimental Dentistry"},{"key":"e_1_2_12_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tripleo.2003.07.006"},{"key":"e_1_2_12_28_1","first-page":"472","article-title":"Do resin\u2010based root canal sealers cause more postoperative pain than other sealers? 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