{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,9]],"date-time":"2026-10-09T12:45:38Z","timestamp":1791549938980,"version":"4.3.4"},"reference-count":44,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2022,12,4]],"date-time":"2022-12-04T00:00:00Z","timestamp":1670112000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Int Endodontic J"],"published-print":{"date-parts":[[2023,3]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Aim<\/jats:title>\n                    <jats:p>The aim of this study was to assess and compare the clinical and radiographic outcome of partial pulpotomy and full pulpotomy using Biodentine in cariously exposed mature molar teeth with symptoms indicative of irreversible pulpitis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methodology<\/jats:title>\n                    <jats:p>\n                      This study is an unicentric, double\u2010arm, randomized superiority clinical trial with parallel experimental groups, registered under CTRI (CTRI\/2019\/12\/022559). Fifty mature permanent molar teeth with carious exposures with symptoms indicative of irreversible pulpitis were randomly allocated equally into two groups. Partial pulpotomy (PP) and full pulpotomy (FP) were performed in the first and second group, respectively, following standardized protocols. Exposed pulp tissue was removed up to a depth of 2\u20133\u2009mm for partial pulpotomy, whereas complete coronal pulp tissue was removed up to the level of root orifices for full pulpotomy. Haemostasis was achieved with placement of 2.5% sodium hypochlorite\u2010moistened cotton pellets placed on amputated pulp tissue for a maximum of 10\u00a0min. Biodentine was used as the pulp capping material. Pain scores were evaluated using 11\u2010point Visual Analogue Scale (VAS) preoperatively, at 24\u2009h, 48\u2009h and 7th day after the intervention(s). Clinical and radiographic evaluation was done at 3\u00a0months, 6\u00a0months and 1\u00a0year. The data were statistically analysed using chi\u2010squared test, Mann\u2013Whitney\n                      <jats:italic>U<\/jats:italic>\n                      \u2010test, Friedman's test and Wilcoxon signed\u2010rank test. The significance level was pre\u2010determined at\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&lt;\u2009.05. Cumulative survival probabilities were assessed at 12\u2009months using Kaplan\u2013Meier analysis.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Intra\u2010group analysis of pain scores revealed significant reduction in pain scores preoperatively and at 24\u2009h, 48\u2009h and 7th day in both the groups. However, the difference in the pain score(s) reduction between both the groups was not statistically significant at any time interval (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&gt;\u2009.05). At 1\u2010year follow\u2010up, the success rate was 88% (22\/25) and 91.6% (22\/24) for PP and FP respectively (\n                      <jats:italic>p<\/jats:italic>\n                      \u2009&gt;\u2009.05).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Partial pulpotomy showed comparable results to full pulpotomy in terms of clinical\/radiographic treatment outcome. If the long\u2010term results remain the same, partial pulpotomy can be proposed as an alternative treatment modality for mature teeth with cariously exposed pulp tissue presenting with signs of symptomatic irreversible pulpitis.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/iej.13872","type":"journal-article","created":{"date-parts":[[2022,11,20]],"date-time":"2022-11-20T09:44:17Z","timestamp":1668937457000},"page":"331-344","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":82,"title":["Outcome of partial and full pulpotomy in cariously exposed mature molars with symptoms indicative of irreversible pulpitis: A randomized controlled trial"],"prefix":"10.1111","volume":"56","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2431-3226","authenticated-orcid":false,"given":"Ashima","family":"Jassal","sequence":"first","affiliation":[{"name":"Department of Conservative Dentistry and Endodontics Maulana Azad Institute of Dental Sciences  New Delhi India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7264-8506","authenticated-orcid":false,"given":"Ruchika Roongta","family":"Nawal","sequence":"additional","affiliation":[{"name":"Department of Conservative Dentistry and Endodontics Maulana Azad Institute of Dental Sciences  New Delhi India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6711-4665","authenticated-orcid":false,"given":"Seema","family":"Yadav","sequence":"additional","affiliation":[{"name":"Department of Conservative Dentistry and Endodontics Maulana Azad Institute of Dental Sciences  New Delhi India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6805-4695","authenticated-orcid":false,"given":"Sangeeta","family":"Talwar","sequence":"additional","affiliation":[{"name":"Department of Conservative Dentistry and Endodontics Maulana Azad Institute of Dental Sciences  New Delhi India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5656-4628","authenticated-orcid":false,"given":"Sudha","family":"Yadav","sequence":"additional","affiliation":[{"name":"Department of Conservative Dentistry and Endodontics Maulana Azad Institute of Dental Sciences  New Delhi India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8690-2379","authenticated-orcid":false,"given":"Henry Fergus","family":"Duncan","sequence":"additional","affiliation":[{"name":"Division of Restorative Dentistry Dublin Dental University Hospital, Trinity College Dublin  Dublin Ireland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2022,12,4]]},"reference":[{"key":"e_1_2_13_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.joen.2021.07.015"},{"key":"e_1_2_13_3_1","first-page":"19","article-title":"Evaluation of mineral 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