{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T10:47:45Z","timestamp":1787050065598,"version":"build-2736575974"},"reference-count":47,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[2024,2,7]],"date-time":"2024-02-07T00:00:00Z","timestamp":1707264000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Int Endodontic J"],"published-print":{"date-parts":[[2024,5]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>There is an increased tendency towards adopting minimally invasive interventions in dentistry, supported by advancement in materials and techniques. However, the decision\u2010making process in choosing conservative or invasive treatments is influenced by several factors, particularly in permanent teeth with irreversible pulpitis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>The objective of the study was to systematically review the literature regarding factors that influence decision\u2010making for vital pulp therapy (VPT) as definitive treatment option in permanent mature teeth diagnosed with irreversible pulpitis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Two independent reviewers searched five electronic databases (PubMed, Embase, Web of Science, Scopus and Cochrane Library). Grey literature was searched through Google Scholar and contact with experts. Defined search keys were applied, and all peer\u2010reviewed literature published with no language nor publication date limits were included. The All studies investigating the factors influencing treatment decision\u2010making in mature permanent teeth with irreversible pulpitis were included. The quality of included studies was assessed by two independent reviewers using the Joanna Briggs Institute quality assessment tool.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Six articles were included in the review. All included studies used questionnaires to characterize clinician preferences and attitudes in choosing treatment options for mature permanent teeth with irreversible pulpitis. The available evidence suggests that dentist\u2010related factors have a significant influence on the chosen treatment in teeth with irreversible pulpitis, with speciality training and years of experience influencing the choice of VPT over other treatment options. COVID\u201019 reportedly swayed the dentists\u2019 decision to favour VPT. Only one article studied the influence of patient\u2010related factors, such as age and presence of spontaneous pain on decision\u2010making. Of note, a history of cardiovascular disease moved dentists towards prescribing VPT.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Discussion<\/jats:title>\n                    <jats:p>Collectively, the included studies demonstrated an overriding influence of dentist\u2010related factors on choosing among treatment options for painful teeth diagnosed with irreversible pulpitis. Patient\u2010related factors were acknowledged but there are also potential factors such as socio\u2010economic constraints that were not included in the component studies.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>In teeth with irreversible pulpitis clinicians educational background influence the decision towards a specific treatment option. Further data, preferably derived from clinical records, is necessary in future investigations to explore the effect of other important factors related to both dentists and patients.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Registration<\/jats:title>\n                    <jats:p>PROSPERO database (CRD42022339653).<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1111\/iej.14036","type":"journal-article","created":{"date-parts":[[2024,2,7]],"date-time":"2024-02-07T22:58:50Z","timestamp":1707346730000},"page":"505-519","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":26,"title":["Vital pulp therapy\u2014Factors influencing decision\u2010making for permanent mature teeth with irreversible pulpitis: A systematic review"],"prefix":"10.1111","volume":"57","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5378-5978","authenticated-orcid":false,"given":"Yasmen","family":"Alfaisal","sequence":"first","affiliation":[{"name":"School of Dentistry The University of Queensland  Brisbane Queensland Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8654-6562","authenticated-orcid":false,"given":"Ghassan","family":"Idris","sequence":"additional","affiliation":[{"name":"Metro North Hospital and Health Services, Queensland Health  Brisbane Queensland Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5222-8718","authenticated-orcid":false,"given":"Ove A.","family":"Peters","sequence":"additional","affiliation":[{"name":"School of Dentistry The University of Queensland  Brisbane Queensland 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