{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,9]],"date-time":"2026-10-09T12:45:33Z","timestamp":1791549933642,"version":"4.3.4"},"reference-count":24,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2024,10,1]],"date-time":"2024-10-01T00:00:00Z","timestamp":1727740800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Int Endodontic J"],"published-print":{"date-parts":[[2025,1]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>The aim of this study is to compare the outcomes of restricted partial pulpotomy (R\u2010PP) versus extended partial pulpotomy (E\u2010PP) for managing cariously exposed mature permanent molars with symptomatic irreversible pulpitis (SIP).<\/jats:p><\/jats:sec><jats:sec><jats:title>Methodology<\/jats:title><jats:p>This double\u2010arm, parallel designed randomized clinical trial was registered at <jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" xlink:href=\"http:\/\/clinicaltrials.gov\">clinicaltrials.gov<\/jats:ext-link> (registration number: NCT05406557). Following random allocation, 43 participants of each group received the designated intervention. In the R\u2010PP group, 2\u20133\u2009mm of superficial pulp tissue was removed only from the exposure site, while chamber was completely de\u2010roofed and 2\u20133\u2009mm of superficial pulp tissue from entire chamber was removed in the E\u2010PP group. Haemostasis was achieved using 3% sodium hypochlorite\u2010soaked cotton pellets. Upon haemostasis, ProRoot mineral trioxide aggregate (ProRoot MTA) was placed over the pulpal wound, overlaid with a resin\u2010modified glass ionomer liner, and restored with composite resin in the same visit. Outcome measures included clinical and radiographic success evaluation at 6 and 12\u2009months, and pain assessment using the visual analogue scale pre\u2010operatively and daily for 7 post\u2010operative days. Nonparametric tests were used for variables including patient's age, pain intensities, mean analgesic consumption, and haemostasis time. Categorical variables including gender, caries type, analgesic intake, hard tissue barrier formation, clinical and radiographic success, and pulp sensibility responses were assessed using Chi\u2010square or Fisher's exact test. Tooth survival was analysed using Kaplan\u2013Meier analysis.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>A total of 81 cases were analysed at 12\u2009months follow\u2010up. Comparable success was observed in both groups (97.6% in E\u2010PP &amp; 97.5% in R\u2010PP; <jats:italic>p<\/jats:italic>\u2009&gt;\u2009.05). The R\u2010PP group reported significantly lower pain scores on the 1st and 2nd post\u2010operative days than E\u2010PP (<jats:italic>p<\/jats:italic>\u2009&lt;\u2009.05) and required significantly less analgesic intake (<jats:italic>p<\/jats:italic>\u2009&lt;\u2009.05). Hard tissue barrier formation was significantly lower in the R\u2010PP group (<jats:italic>p<\/jats:italic>\u2009&lt;\u2009.05). No significant differences were observed between groups regarding haemostasis time, pulp sensibility responses, and tooth survival (<jats:italic>p<\/jats:italic>\u2009&gt;\u2009.05).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Both the PP approaches exhibited comparable success for managing cariously exposed mature permanent molars with SIP. Given the conservative nature of R\u2010PP, it may be used as preferred PP approach for managing such cases. Being the first study of this kind, further work is necessary to draw definitive conclusions.<\/jats:p><\/jats:sec>","DOI":"10.1111\/iej.14152","type":"journal-article","created":{"date-parts":[[2024,10,1]],"date-time":"2024-10-01T14:03:18Z","timestamp":1727791398000},"page":"71-83","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":8,"title":["Effect of lateral extent of pulp tissue removal on the outcome of partial pulpotomy for managing cariously exposed mature permanent molars with symptomatic irreversible pulpitis: A randomized clinical trial"],"prefix":"10.1111","volume":"58","author":[{"given":"A.","family":"Ramani","sequence":"first","affiliation":[{"name":"Department of Conservative Dentistry and Endodontics PGIDS  Rohtak India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1851-8978","authenticated-orcid":false,"given":"P.","family":"Sangwan","sequence":"additional","affiliation":[{"name":"Department of Conservative Dentistry and Endodontics PGIDS  Rohtak India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.","family":"Duhan","sequence":"additional","affiliation":[{"name":"Department of Conservative Dentistry and Endodontics PGIDS  Rohtak India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.","family":"Popat","sequence":"additional","affiliation":[{"name":"Department of Head &amp; Neck Oncology Medanta\u2010the Medicity  Gurugram India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Sangwan","sequence":"additional","affiliation":[{"name":"Department of Periodontics &amp; Oral Implantology PGIDS  Rohtak India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2024,10]]},"reference":[{"key":"e_1_2_13_2_1","unstructured":"AAE \u2010 American Association of Endodontists. (2019)Glossary of terms. Available from:https:\/\/www.aae.org\/specialty\/clinicalresources\/glossary\u2010endodontic\u2010terms\/[Accessed on 16 May 2024]"},{"key":"e_1_2_13_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.joen.2021.10.005"},{"key":"e_1_2_13_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.joen.2017.12.010"},{"key":"e_1_2_13_5_1","doi-asserted-by":"publisher","DOI":"10.3390\/jcm9082408"},{"key":"e_1_2_13_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/iej.13128"},{"key":"e_1_2_13_7_1","doi-asserted-by":"publisher","DOI":"10.1111\/iej.13629"},{"key":"e_1_2_13_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jdent.2019.06.005"},{"key":"e_1_2_13_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/iej.13424"},{"key":"e_1_2_13_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/iej.13688"},{"key":"e_1_2_13_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/iej.13866"},{"key":"e_1_2_13_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/iej.13080"},{"key":"e_1_2_13_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.joen.2019.07.005"},{"key":"e_1_2_13_14_1","doi-asserted-by":"publisher","DOI":"10.1002\/acr.20345"},{"key":"e_1_2_13_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/iej.13872"},{"key":"e_1_2_13_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/0030-4220(65)90166-0"},{"key":"e_1_2_13_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/iej.13294"},{"key":"e_1_2_13_18_1","doi-asserted-by":"publisher","DOI":"10.1111\/iej.13714"},{"key":"e_1_2_13_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.joen.2014.08.010"},{"key":"e_1_2_13_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jdent.2019.05.022"},{"key":"e_1_2_13_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.joen.2020.06.025"},{"key":"e_1_2_13_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.joen.2024.03.012"},{"key":"e_1_2_13_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.joen.2017.03.033"},{"key":"e_1_2_13_24_1","doi-asserted-by":"publisher","DOI":"10.1111\/iej.13955"},{"key":"e_1_2_13_25_1","doi-asserted-by":"publisher","DOI":"10.1111\/iej.13071"}],"container-title":["International Endodontic Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1111\/iej.14152","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,12,10]],"date-time":"2024-12-10T07:35:40Z","timestamp":1733816140000},"score":1,"resource":{"primary":{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/10.1111\/iej.14152"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,10]]},"references-count":24,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2025,1]]}},"alternative-id":["10.1111\/iej.14152"],"URL":"https:\/\/doi.org\/10.1111\/iej.14152","archive":["Portico"],"relation":{},"ISSN":["0143-2885","1365-2591"],"issn-type":[{"value":"0143-2885","type":"print"},{"value":"1365-2591","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,10]]},"assertion":[{"value":"2024-05-30","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-09-19","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-10-01","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}