{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,2]],"date-time":"2026-07-02T19:01:26Z","timestamp":1783018886037,"version":"3.54.6"},"reference-count":28,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[2025,1,14]],"date-time":"2025-01-14T00:00:00Z","timestamp":1736812800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Int Endodontic J"],"published-print":{"date-parts":[[2025,3]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:sec><jats:title>Aim<\/jats:title><jats:p>The objective of pulpotomy is to preserve the pulp vitality. However, the assessment of pulpal status following pulpotomy is often overlooked. This retrospective analysis aimed to compare the pulp responses to EPT (Electric pulp test) and cold test in mature permanent molars that have undergone either complete pulpotomy (CP) or partial pulpotomy (PP) for managing carious pulpal exposure and symptomatic irreversible pulpitis (SIP) and completed 12\u2009months follow\u2010up.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methodology<\/jats:title><jats:p>This retrospective analysis pooled data from three randomized clinical trials of pulpotomy (one using CP and two using PP) conducted in the Department of Conservative Dentistry and Endodontics of the Postgraduate Institute of Dental Sciences, Rohtak, from December 2020 to May 2024. The present study included a total of 220 cariously exposed mature permanent molars with SIP, that underwent either CP (<jats:italic>n<\/jats:italic>\u2009=\u200945) or PP (<jats:italic>n<\/jats:italic>\u2009=\u2009175) using ProRoot Mineral Trioxide Aggregate, and were followed\u2010up for 12\u2009months. The teeth were evaluated for outcomes (clinical and radiographic), and pulp sensibility responses to EPT and the cold test, both individually and collectively as positive response to either test. Pulp sensibility responses were further analysed following teeth distribution considering variables like age, gender, number of tooth surfaces restored, preoperative pain intensity and hard tissue formation. Statistical analysis was performed using the Chi\u2010squared test, Fisher's exact test and Mann\u2013Whitney <jats:italic>U<\/jats:italic>\u2010test, with significance at <jats:italic>p<\/jats:italic>\u2009&lt;\u2009.05.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>At 12\u2009months follow\u2010up, 209 of 220 teeth analysed had a successful pulpotomy outcome. Amongst these, PP\u2010treated teeth responded more predictably to EPT and cold test as compared to CP\u2010treated teeth. However, the difference was significant with EPT analysis only (<jats:italic>p<\/jats:italic>\u2009=\u2009.001). The proportion of teeth with a positive response was significantly higher in both the groups, when considering a combined positive response to either EPT or cold test, compared to the positive response to each test alone (<jats:italic>p<\/jats:italic>\u2009&lt;\u2009.001). None of the included variables influenced the pulp sensibility responses in either group (<jats:italic>p<\/jats:italic>\u2009&gt;\u2009.05).<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>PP\u2010treated teeth responded more predictably to EPT and cold test than CP\u2010treated teeth. Future studies must consider positive response to either EPT or the cold test collectively, whilst assessing the pulpal status following CP and PP.<\/jats:p><\/jats:sec>","DOI":"10.1111\/iej.14188","type":"journal-article","created":{"date-parts":[[2025,1,15]],"date-time":"2025-01-15T05:39:52Z","timestamp":1736919592000},"page":"420-433","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":3,"title":["Pulp sensibility responses following complete and partial pulpotomy in mature permanent molars with carious pulpal exposure and symptomatic irreversible pulpitis: Analysis of pooled data from three randomized clinical trials"],"prefix":"10.1111","volume":"58","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1851-8978","authenticated-orcid":false,"given":"Pankaj","family":"Sangwan","sequence":"first","affiliation":[{"name":"Department of Conservative Dentistry and Endodontics Post Graduate Institute of Dental Sciences  Rohtak India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ankita","family":"Ramani","sequence":"additional","affiliation":[{"name":"Department of Conservative Dentistry and Endodontics Post Graduate Institute of Dental Sciences  Rohtak India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Soumyashree","family":"Mishra","sequence":"additional","affiliation":[{"name":"Department of Conservative Dentistry and Endodontics Post Graduate Institute of Dental Sciences  Rohtak India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kanaga","family":"Durga","sequence":"additional","affiliation":[{"name":"Department of Dentistry AIIMS  Raipur India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shyam","family":"Popat","sequence":"additional","affiliation":[{"name":"Department of Head &amp; Neck Oncology Medanta\u2010the Medicity  Gurugram India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aditi","family":"Sangwan","sequence":"additional","affiliation":[{"name":"Department of Periodontics &amp; Oral Implantology Post Graduate Institute of Dental Sciences  Rohtak India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2025,1,14]]},"reference":[{"key":"e_1_2_14_2_1","unstructured":"AAE\u2013American Association of Endodontists. 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